Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alexandre Desaintjean"'
Publikováno v:
Molecules, Vol 25, Iss 3, p 723 (2020)
Various substituted bis-(aryl)manganese species were prepared from aryl bromides by one-pot insertion of magnesium turnings in the presence of LiCl and in situ trans-metalation with MnCl2 in THF at −5 °C within 2 h. These bis-(aryl)manganese reage
Externí odkaz:
https://doaj.org/article/76d544aa42324dd6b679b4f45d2cb000
Publikováno v:
Synthesis. 53:4662-4671
Regioselective I/Zn-exchange reactions were performed on polyiodinated arenes or heterocycles within 20 minutes at 0–25 °C using the bimetallic combination pTol2Zn·2LiOR [R = (CH2)2N(Me)(CH2)2NMe2] in toluene. The resulting diaryl- or diheteroary
Publikováno v:
Synthesis. 53:4461-4476
A wide range of polyfunctionalized di(hetero)aryl- and dialkenyl-magnesium reagents are prepared in toluene within 10 to 120 minutes between –78 °C and 25 °C via an I/Mg- or Br/Mg-exchange reaction using reagents of the general formula R2Mg (R =
Publikováno v:
Desaintjean, Alexandre; Haupt, Tobias; Bole, Leonie J.; Judge, Neil R.; Hevia, Eva; Knochel, Paul (2021). Regioselective Bromine/Magnesium Exchange for the Selective Functionalization of Polyhalogenated Arenes and Heterocycles. Angewandte Chemie (International ed.), 60(3), pp. 1513-1518. Wiley-VCH 10.1002/anie.202012496
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International Ed. in English)
Using the bimetallic combination sBu2Mg⋅2 LiOR (R=2‐ethylhexyl) in toluene enables efficient and regioselective Br/Mg exchanges with various dibromo‐arenes and ‐heteroarenes under mild reaction conditions and provides bromo‐substituted magn
Publikováno v:
Angewandte Chemie. 133:1536-1541
Autor:
Alexandre Desaintjean, Paul Knochel, Eva Hevia, Dorothée Ziegler, Moritz Balkenhohl, Alan R. Kennedy, Leonie J. Bole
Publikováno v:
Angewandte Chemie. 131:13030-13034
Publikováno v:
Organic Letters
Organic Letters, American Chemical Society, 2019, 21, pp.8684-8688. ⟨10.1021/acs.orglett.9b03292⟩
Organic Letters, 2019, 21, pp.8684-8688. ⟨10.1021/acs.orglett.9b03292⟩
Organic Letters, American Chemical Society, 2019, 21, pp.8684-8688. ⟨10.1021/acs.orglett.9b03292⟩
Organic Letters, 2019, 21, pp.8684-8688. ⟨10.1021/acs.orglett.9b03292⟩
International audience; Various substituted benzylic manganese chlorides were prepared by insertion of magnesium turnings in the presence of MnCl2·2LiCl in THF at −5 °C within 2 h. These benzylic manganese reagents underwent smooth cross-coupling
Publikováno v:
Synthesis. 49:5396-5412
A catalytic system consisting of Ni(acac)2 (5 mol%) and 4-fluorostyrene (20 mol%) allows a convenient cross-coupling of functionalized organomanganese reagents with a variety of aryl and heteroaryl halides leading to polyfunctionalized diaryl- and ar
Preparation of Polyfunctional Arylzinc Organometallics in Toluene by Halogen/Zinc Exchange Reactions
Autor:
Alan R. Kennedy, Dorothée Ziegler, Leonie J. Bole, Alexandre Desaintjean, Eva Hevia, Moritz Balkenhohl, Paul Knochel
Publikováno v:
Angewandte Chemie (International ed. in English). 58(37)
A wide range of polyfunctional diaryl-and diheteroarylzinc species were prepared in toluene within 10 min to 5 h through an I/Zn or Br/Zn exchange reaction using bimetallic reagents of the general formula R’2Zn·2LiOR (R’=sBu, tBu, pTol). Highly
Autor:
Johannes H. Harenberg, Maximilian A. Ganiek, Niels Weidmann, Paul Knochel, Alexandre Desaintjean, Benjamin Heinz
Publikováno v:
Opérations unitaires. Génie de la réaction chimique.
Cet article decrit la preparation d’especes organometalliques du magnesium et du zinc et leur emploi en flux continu. Par des reactions de metallations de systemes aromatiques et heterocycliques, il est possible de preparer des magnesiens et zinciq