Biomimetic device and foreign body reaction cooperate for efficient tumour cell capture in murine advanced ovarian cancer

Autor: Lorena Alonso-Alconada, Alexandre de la Fuente, María Santacana, Alba Ferreiros, Rafael Lopez-Lopez, Xavier Matias-Guiu, Miguel Abal

Publikováno v: Disease Models & Mechanisms, Vol 13, Iss 6 (2020)

Metastasis is facilitated by the formation of pre-metastatic niches through the remodelling of the extracellular matrix (ECM) promoted by haematopoietic and stromal cells. The impact of these primed sites is pronounced for intraperitoneal metastases,

Externí odkaz: https://doaj.org/article/aeb9f9f12c18479fbffaf3d2f2d5986a

Enzyme-Loaded Gel Core Nanostructured Lipid Carriers to Improve Treatment of Lysosomal Storage Diseases: Formulation and In Vitro Cellular Studies of Elosulfase Alfa-Loaded Systems

Autor: J. Víctor Álvarez, Carolina Herrero Filgueira, Alexandre de la Fuente González, Cristóbal Colón Mejeras, Andrés Beiras Iglesias, Shunji Tomatsu, José Blanco Méndez, Asteria Luzardo Álvarez, María Luz Couce, Francisco J. Otero Espinar

Publikováno v: Pharmaceutics, Vol 11, Iss 10, p 522 (2019)

Mucopolysaccharidosis IVA (Morquio A) is a rare inherited metabolic disease caused by deficiency of the lysosomal enzyme N-acetylgalatosamine-6-sulfate-sulfatase (GALNS). Until now, treatments employed included hematopoietic stem cell transplantation

Externí odkaz: https://doaj.org/article/a123f631e56c40dab3d1d83b018f860e

Impact of Extracellular Vesicle Isolation Methods on Downstream miRNA Analysis in Semen: A Comparative Study

Autor: Lluís Bassas, Manel Castells, F. Vigués, Olga López-Rodrigo, Alexandre de la Fuente, Carolina Herrero, Marina Mercadal, Sara Larriba

Publikováno v: International Journal of Molecular Sciences
Dipòsit Digital de la UB
Universidad de Barcelona
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 5949, p 5949 (2020)

Seminal plasma (SP) contains a unique concentration of miRNA, mostly contained in small extracellular vesicles (sEVs) such as exosomes, some of which could be clinically useful for diagnosis and/or prognosis of urogenital diseases such as prostate ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd6ca2f9d9247b0a5be813006e098cf
http://europepmc.org/articles/PMC7504614

3, 3′, 5-triiodo-L-thyronine Increases In Vitro Chondrogenesis of Mesenchymal Stem Cells From Human Umbilical Cord Stroma Through SRC2

Autor: Fco. Blanco García, M.C. Arufe, Javier De Toro Santos, Alexandre De la Fuente, Iván Lesende-Rodriguez, I. Fuentes, Jesús Mateos, P. Fernández-Pernas, Juan Fafián-Labora

Publikováno v: Journal of Cellular Biochemistry. 117:2097-2108

Our group focuses on the study of mesenchymal stem cells (MSCs) from human umbilical cord stroma or Warthons jelly and their directed differentiation toward chondrocyte-like cells capable of regenerating damaged cartilage when transplanted into an in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07ab16cbbc746ddcfe53568a4c22cf9c
https://doi.org/10.1002/jcb.25515

CD105+-Mesenchymal Stem Cells Migrate into Osteoarthritis Joint: an Animal Model

Autor: P. Fernández-Pernas, Jesús Mateos, Iván Rodríguez-Lesende, I. Fuentes, Fco J. Blanco, M.C. Arufe, Alexandre De la Fuente, Javier de Toro

Publikováno v: RUC. Repositorio da Universidade da Coruña
instname
PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0188072 (2017)

[Abstract] Mesenchymal stem cells are being the focus of connective tissue technology and regenerative medicine, presenting a good choice cell source for improving old and well recognized techniques of cartilage defect repair. For instance, the autol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723f8c6188a28ddec6113590f82f6a55
http://hdl.handle.net/2183/19958