Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Alexandre Colavin"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Despite the structural and functional information contained in the statistical coupling between pairs of residues in a protein, coevolution associated with function is often obscured by artifactual signals such as genetic drift, which shapes
Externí odkaz:
https://doaj.org/article/e2a7e865263d40a9aab2c63c72273acb
Autor:
Britt Johnson, Ana Morales, Flavia Facio, Laure Fresard, Dianalee McKnight, Yuya Kobayashi, Jason Reuter, Keith Nykamp, Swaroop Aradhya, Alexandre Colavin
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100537- (2023)
Externí odkaz:
https://doaj.org/article/d196dce84dae4adcbcf71f28bca953bb
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Membrane protein RodZ interacts with the actin-like protein MreB, which coordinates cell-wall insertion to maintain the typical rod-like shape of E. coli cells. Here, the authors provide evidence that RodZ modulates the biophysical properties of MreB
Externí odkaz:
https://doaj.org/article/b9d890ceabe244c0a401c4b57881a85c
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2592-2599 (2017)
G6PD deficiency, an enzymopathy affecting 7% of the world population, is caused by over 160 identified amino acid variants in glucose-6-phosphate dehydrogenase (G6PD). The clinical presentation of G6PD deficiency is diverse, likely due to the broad d
Externí odkaz:
https://doaj.org/article/9fbe5673bfb84a87893e44ff61f61046
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 4, p e1006683 (2019)
The actin family of cytoskeletal proteins is essential to the physiology of virtually all archaea, bacteria, and eukaryotes. While X-ray crystallography and electron microscopy have revealed structural homologies among actin-family proteins, these te
Externí odkaz:
https://doaj.org/article/9de135470a34456aa9a8bd68297d768c
Autor:
Russell D. Monds, Timothy K. Lee, Alexandre Colavin, Tristan Ursell, Selwyn Quan, Tim F. Cooper, Kerwyn Casey Huang
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1528-1537 (2014)
Diversification of cell size is hypothesized to have occurred through a process of evolutionary optimization, but direct demonstrations of causal relationships between cell geometry and fitness are lacking. Here, we identify a mutation from a laborat
Externí odkaz:
https://doaj.org/article/5b80144c5c8f479bad87daa864be0ea6
Autor:
Andrew N Gray, Alexander JF Egan, Inge L van't Veer, Jolanda Verheul, Alexandre Colavin, Alexandra Koumoutsi, Jacob Biboy, A F Maarten Altelaar, Mirjam J Damen, Kerwyn Casey Huang, Jean-Pierre Simorre, Eefjan Breukink, Tanneke den Blaauwen, Athanasios Typas, Carol A Gross, Waldemar Vollmer
Publikováno v:
eLife, Vol 4 (2015)
To maintain cellular structure and integrity during division, Gram-negative bacteria must carefully coordinate constriction of a tripartite cell envelope of inner membrane, peptidoglycan (PG), and outer membrane (OM). It has remained enigmatic how th
Externí odkaz:
https://doaj.org/article/04fecc86150049b7bfec873c33e51564
Autor:
Warren van Loggerenberg, Shahin Sowlati-Hashjin, Jochen Weile, Rayna Hamilton, Aditya Chawla, Marinella Gebbia, Nishka Kishore, Laure Frésard, Sami Mustajoki, Elena Pischik, Elena Di Pierro, Michela Barbaro, Ylva Floderus, Caroline Schmitt, Laurent Gouya, Alexandre Colavin, Robert Nussbaum, Edith C. H. Friesema, Raili Kauppinen, Jordi To-Figueras, Aasne K. Aarsand, Robert J. Desnick, Michael Garton, Frederick P. Roth
Publikováno v:
bioRxiv. Cold Spring Harbor Laboratory Press
bioRxiv
bioRxiv
Defects in hydroxymethylbilane synthase (HMBS) can cause Acute Intermittent Porphyria (AIP), an acute neurological disease. Although sequencing-based diagnosis can be definitive, ~⅓ of clinical HMBS variants are missense variants, and most clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5a11044cd46f85fd47c0eccc53c389
https://doi.org/10.1101/2023.02.06.527353
https://doi.org/10.1101/2023.02.06.527353
Autor:
Ana Ana Morales, Britt Johnson, Matteo Vatta, Flavia Facio, Laure Fresard, Dianalee McKnight, Yuya Kobayashi, Jason Reuter, Swaroop Aradhya, Keith Nykamp, Alexandre Colavin
Publikováno v:
Heart Rhythm. 20:S30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e94c9dc008f88bb28b32b6d3a2217b73
https://doi.org/10.1016/j.hrthm.2023.03.260
https://doi.org/10.1016/j.hrthm.2023.03.260
Autor:
Britt Johnson, Ana Morales, Flavia Facio, Laure Fresard, Dianalee McKnight, Yuya Kobayashi, Jason Reuter, Swaroop Aradhya, Keith Nykamp, Alexandre Colavin
Publikováno v:
Clinical Immunology. 250:109469
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b045be21f5a756aaffdfdc8f6e29417
https://doi.org/10.1016/j.clim.2023.109469
https://doi.org/10.1016/j.clim.2023.109469