Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alexandre Boutorine"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1348-1360 (2016)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
Efficient protocols based on Cu(I)-catalyzed azide–alkyne cycloaddition were developed for the synthesis of conjugates of pyrrole–imidazole polyamide minor groove binders (MGB) with fluorophores and with triplex-forming oligonucleotides (TFOs). D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd78dcaf08c0821aa0ff0077a70429f
https://doi.org/10.3762/bjoc.12.128
https://doi.org/10.3762/bjoc.12.128
Autor:
Ludovic Halby, Jean-Paul Concordet, Fabio Cannata, A. N. Sinyakov, Loïc Perrouault, Vladimir A. Ryabinin, Alexandre Boutorine, Carine Giovannangeli, Philippe Simon
Publikováno v:
Nucleic Acids Research
The design of molecules that damage a selected DNA sequence provides a formidable opportunity for basic and applied biology. For example, such molecules offer new prospects for controlled manipulation of the genome. The conjugation of DNA-code readin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0995dce5869b4701e31ff84eb8073251
https://doi.org/10.1093/nar/gkn231
https://doi.org/10.1093/nar/gkn231
Autor:
Paola B. Arimondo, Christian Bailly, Craig J. Thomas, Thérèse Garestier, Jian Sheng Sun, Ludovic Halby, Didier Pez, Sidney M. Hecht, Alexandre Boutorine, Yves Pommier, Gary S. Laco, Philippe Schmitt
Publikováno v:
Biochemistry. 44:4171-4180
Topoisomerase I (topo I) is a ubiquitous DNA-cleaving enzyme and an important therapeutic target in cancer chemotherapy. Camptothecins (CPTs) reversibly trap topo I in covalent complex with DNA but exhibit limited sequence preference. The utilization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6ff156c212636e7d1884b9594dfe9c
https://doi.org/10.1021/bi048031k
https://doi.org/10.1021/bi048031k
Publikováno v:
Journal of mass spectrometry : JMS. 44(8)
A new method for the determination of the relative affinity of a ligand against various dsDNA sequences is presented by using electrospray ionization time-of-flight mass spectrometry (ESI-QTOF) mass spectrometry. The principle is described here throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20359fefdd897a7968452e5b1324a3c6
https://pubmed.ncbi.nlm.nih.gov/19408249
https://pubmed.ncbi.nlm.nih.gov/19408249
Autor:
Claudio Pisano, Ludovic Halby, Christine Mahieu, Domenico Alloatti, Pierre Vekhoff, Lucio Merlini, Alexandre Boutorine, Amélie Lansiaux, Paola B. Arimondo, Christian Bailly, Kahina Oussedik, Giuseppe Giannini, Sabrina Dallavalle
Publikováno v:
Bioconjugate chemistry. 20(4)
Sequence-specific camptothecins are useful tools to inhibit specifically gene expression. The camptothecins are attached to the 3' end of triplex-forming oligonucleotides (TFO), sequence-specific DNA ligands that position the camptothecin moiety excl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83075686603a4cc6fce99ff148db9617
https://pubmed.ncbi.nlm.nih.gov/19309124
https://pubmed.ncbi.nlm.nih.gov/19309124
Autor:
Jean-Marie Lehn, Alexandre Boutorine, Claude Hélène, David M. Perrin, David Polverari, Marie-Paule Teulade-Fichou, Jean-Pierre Vigneron, Jian-Sheng Sun, Thérèse Garestier
Publikováno v:
Journal of the American Chemical Society. 123(38)
Amino-p-quinacridine compounds (PQs) have been shown to stabilize strongly and specifically triple-helical DNA. Moreover, these derivatives display photoactive properties that make them efficient DNA cleavage agents. We exploited these two properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163df5b3bded29bdc468f885d887cee4
https://pubmed.ncbi.nlm.nih.gov/11562210
https://pubmed.ncbi.nlm.nih.gov/11562210