Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alexandre Blanchette"'
Autor:
Delphine M Béziau, Fanny Toussaint, Alexandre Blanchette, Nour R Dayeh, Chimène Charbel, Jean-Claude Tardif, Jocelyn Dupuis, Jonathan Ledoux
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123769 (2015)
Phospholipase C (PLC) comprises a superfamily of enzymes that play a key role in a wide array of intracellular signalling pathways, including protein kinase C and intracellular calcium. Thirteen different mammalian PLC isoforms have been identified a
Externí odkaz:
https://doaj.org/article/108cee6842694178a0602809589d023d
Autor:
Yohann Rautureau, Marianne Berlatie, Daniel Rivas, Kurunradeth Uy, Alexandre Blanchette, Géraldine Miquel, Marie-Ève Higgins, Mélanie Mecteau, Audrey Nault, Louis Villeneuve, Véronique Lavoie, Gabriel Théberge-Julien, Geneviève Brand, Line Lapointe, Maxime Denis, Camille Rosa, Annik Fortier, Lucie Blondeau, Marie-Claude Guertin, Marie-Pierre Dubé, Éric Thorin, Jonathan Ledoux, David Rhainds, Éric Rhéaume, Jean-Claude Tardif
Publikováno v:
Cardiovascular Research. 119:450-464
Aims The adenylate cyclase type 9 (ADCY9) gene appears to determine atherosclerotic outcomes in patients treated with dalcetrapib. In mice, we recently demonstrated that Adcy9 inactivation potentiates endothelial function and inhibits atherogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59dfde35e0ca79a2cd243bb6960b41ac
https://doi.org/10.1093/cvr/cvac085
https://doi.org/10.1093/cvr/cvac085
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae00343e5379fed08238567b6c0d98e0
https://doi.org/10.1096/fasebj.2018.32.1_supplement.703.3
https://doi.org/10.1096/fasebj.2018.32.1_supplement.703.3
Publikováno v:
Cell Calcium. 58:275-285
Localized endothelial Ca 2+ signalling, such as Ca 2+ pulsars, can modulate the contractile state of the underlying vascular smooth muscle cell through specific endothelial targets. In addition to K Ca 3.1 as a target, Ca 2+ pulsars, an IP 3 R-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c44e8a74399f58a13192a39a3001c3f
https://doi.org/10.1016/j.ceca.2015.06.005
https://doi.org/10.1016/j.ceca.2015.06.005
Autor:
Isabelle Dumont, Paul Rhyne, Saadya Fatmi, Curtis Sheldon, Rafiq Islam, Yanseng Liu, Roger Hayes, Dick Tacey, William Nowatzke, Gene Ray, Jenny Lin, Jennifer Bravo, Gary Schultz, Robert Nicholson, Barry van der Strate, Jim Datin, Chad Briscoe, Elizabeth Groeber, Teri Pekol, Tim Lansing, Jordi Ortuno, Rand Jenkins, Ira DuBey, Andrew Roberts, Mike Buonarati, Andrea Watson, Douglas M. Fast, John Lin, John Kamerud, Mathilde Yu, Daniel Tang, Michele Malone, Laura Cojocaru, Allan Xu, Petra Struwe, Masood Khan, Ann Levesque, Richard LeLacheur, Kai Kurylak, Colin Farrell, Steve Lowes, Mohammed Bouhajib, Ronald Shoup, John Doughty, Joseph Bower, Gibran El-Sulayman, Chantal DiMarco, Alexandre Blanchette, Mary Carbone, Phyllis Conliffe, Fabio Garofolo, Dominique Gouty, Jim Hulse, Jamil Hantash, Jennifer Zimmer, Mike Redrup, Scott Reuschel, Sofi Gagnon-Carignan, Maria Cruz Caturla, Mike Allen, Wei Garofolo, Xinping Fang, Shane Karnik
Publikováno v:
Bioanalysis. 6:2957-2963
The 8th GCC Closed Forum for Bioanalysis was held in Baltimore, MD, USA on 5 December 2013, immediately following the 2013 AAPS Workshop (Crystal City V): Quantitative Bioanalytical Methods Validation and Implementation – The 2013 Revised FDA Guida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f65897a65520e2ae7e6f583b208f47fb
https://doi.org/10.4155/bio.14.287
https://doi.org/10.4155/bio.14.287
Autor:
Jonathan Ledoux, Delphine Béziau, Fanny Toussaint, Gaétan Mayer, Alexandre Blanchette, Chimène Charbel
Publikováno v:
The FASEB Journal. 29
Calcium (Ca2+) homeostasis is critical to endothelial function. Indeed, localized endothelial Ca2+ signals, such as Ca2+ pulsars - restricted IP3R-dependent Ca2+ releases within myoendothelial proj...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5640b4d330a56c2a250e158f66319294
https://doi.org/10.1096/fasebj.29.1_supplement.956.2
https://doi.org/10.1096/fasebj.29.1_supplement.956.2
Publikováno v:
Cell calcium. 58(3)
Localized endothelial Ca(2+) signalling, such as Ca(2+) pulsars, can modulate the contractile state of the underlying vascular smooth muscle cell through specific endothelial targets. In addition to K(Ca)3.1 as a target, Ca(2+) pulsars, an IP3R-depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8ab23e2b6c9df71e204e8b3459c9f1a
https://pubmed.ncbi.nlm.nih.gov/26100947
https://pubmed.ncbi.nlm.nih.gov/26100947
Autor:
Jonathan Ledoux, Steven Safar, Marc-Antoine Gillis, Alexandre Blanchette, Nour R. Dayeh, Jocelyn Dupuis
Publikováno v:
The FASEB Journal. 28
Heart failure is the most frequent cause of pulmonary hypertension (PH) (group 2). Pathophysiological mechanisms modulating pulmonary vascular tone and leading to group 2-PH are poorly defined. Since Ca2+ homeostasis is crucial to endothelial control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f8d0921e4400062ab7e2f24896eacfc
https://doi.org/10.1096/fasebj.28.1_supplement.1090.11
https://doi.org/10.1096/fasebj.28.1_supplement.1090.11
Autor:
Philippe Comtois, Fanny Toussaint, Marc-Antoine Gillis, Alexandre Blanchette, Chimène Charbel, Jonathan Ledoux
Publikováno v:
The FASEB Journal. 28
Angiotensin II-induced arterial hypertension (AngII-AH) is associated with an endothelial dysfunction characterized by a Ca2+ dyshomeostasis. Alteration of the delicate balance between reactive oxy...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1446f70815a2ff136715db1dc975988e
https://doi.org/10.1096/fasebj.28.1_supplement.851.6
https://doi.org/10.1096/fasebj.28.1_supplement.851.6
Autor:
Delphine Béziau, Nour Daya, Alexandre Blanchette, Chimène Charbel, Jonathan Ledoux, Fanny Toussaint
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a33fad4d773a5827d0270c72aa4edc
https://doi.org/10.1096/fasebj.28.1_supplement.1075.2
https://doi.org/10.1096/fasebj.28.1_supplement.1075.2