Zobrazeno 1 - 3
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pro vyhledávání: '"Alexandre Audic"'
Autor:
Joëlle Prunet, Alexandre Audic
Publikováno v:
Synthesis.
Diverse approaches to prepare the nine-membered ring precursor of the DEF fragment of hexacyclinic acid are described, culminating in the synthesis of the CDF ring system of this natural product. The key steps are a Michael addition/elimination seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce8a17b4b3e44b355048bf339c4b3711
https://doi.org/10.1055/a-2022-1809
https://doi.org/10.1055/a-2022-1809
During our studies toward the synthesis of the ABC ring system of hexacyclinic acid, we observed an unexpected influence of the steric bulk of the ester group of the Michael acceptor in a key conjugate addition. We propose an eight-membered ring tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5c8b8b5cf2125f90ae3231ad3e7de4
https://eprints.gla.ac.uk/226613/2/226613.pdf
https://eprints.gla.ac.uk/226613/2/226613.pdf
Publikováno v:
Organic letters. 21(3)
A silicon-tether ring-closing metathesis strategy is reported for the synthesis of trisubstituted olefins flanked by allylic or homoallylic alcohols, which are difficult to obtain by classical ring-closing or cross-metathesis reactions. In addition,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73bd73da2c37ac5f022f260bb1d6494
https://pubmed.ncbi.nlm.nih.gov/30589270
https://pubmed.ncbi.nlm.nih.gov/30589270