Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alexandre Alcais"'
Autor:
Monica Dallmann-Sauer, Yong Zhong Xu, Ana Lúcia França da Costa, Shao Tao, Tiago Araujo Gomes, Rhana Berto da Silva Prata, Wilian Correa-Macedo, Jérémy Manry, Alexandre Alcaïs, Laurent Abel, Aurélie Cobat, Vinicius M Fava, Roberta Olmo Pinheiro, Flavio Alves Lara, Christian M Probst, Marcelo T Mira, Erwin Schurr
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011260 (2023)
Leprosy, caused by Mycobacterium leprae, rarely affects children younger than 5 years. Here, we studied a multiplex leprosy family that included monozygotic twins aged 22 months suffering from paucibacillary leprosy. Whole genome sequencing identifie
Externí odkaz:
https://doaj.org/article/4ecae232e9fb4df9b33a140cb5f24d8c
Autor:
Matthieu Bouaziz, Jimmy Mullaert, Benedetta Bigio, Yoann Seeleuthner, Jean-Laurent Casanova, Alexandre Alcais, Laurent Abel, Aurélie Cobat
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Population stratification is a confounder of genetic association studies. In analyses of rare variants, corrections based on principal components (PCs) and linear mixed models (LMMs) yield conflicting conclusions. Studies evaluating these ap
Externí odkaz:
https://doaj.org/article/9db841d81fa14f6ea5b6aeb498a35477
PARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages.
Autor:
Louis de Léséleuc, Marianna Orlova, Aurelie Cobat, Manon Girard, Nguyen Thu Huong, Nguyen Ngoc Ba, Nguyen Van Thuc, Richard Truman, John S Spencer, Linda Adams, Vu Hong Thai, Alexandre Alcais, Erwin Schurr
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 1, p e2015 (2013)
Leprosy is a persistent infectious disease caused by Mycobacterium leprae that still affects over 200,000 new patients annually. The host genetic background is an important risk factor for leprosy susceptibility and the PARK2 gene is a replicated lep
Externí odkaz:
https://doaj.org/article/ccd2ff949089414687389e85f722980d
Autor:
Stéphanie Boisson-Dupuis, Jamila El Baghdadi, Nima Parvaneh, Aziz Bousfiha, Jacinta Bustamante, Jacqueline Feinberg, Arina Samarina, Audrey V Grant, Lucile Janniere, Naima El Hafidi, Amal Hassani, Daniel Nolan, Jilali Najib, Yildiz Camcioglu, Nevin Hatipoglu, Cigdem Aydogmus, Gonul Tanir, Caner Aytekin, Melike Keser, Ayper Somer, Guside Aksu, Necil Kutukculer, Davood Mansouri, Alireza Mahdaviani, Setareh Mamishi, Alexandre Alcais, Laurent Abel, Jean-Laurent Casanova
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18524 (2011)
In the last decade, autosomal recessive IL-12Rβ1 deficiency has been diagnosed in four children with severe tuberculosis from three unrelated families from Morocco, Spain, and Turkey, providing proof-of-principle that tuberculosis in otherwise healt
Externí odkaz:
https://doaj.org/article/371611f76da547a09747d5270c01ce63
Autor:
Alain Fischer, Johan Provot, Jean-Philippe Jais, Alexandre Alcais, Nizar Mahlaoui, Daniel Adoue, Nathalie Aladjidi, Zahir Amoura, Philippe Arlet, Corinne Armari-Alla, Brigitte Bader-Meunier, Vincent Barlogis, Sophie Bayart, Beatrice Beaurain, Yves Bertrand, Boris Bienvenu, Stéphane Blanche, Damien Bodet, Bernard Bonnotte, Raphaël Borie, Patrick Boutard, Claire Briandet, Jean-Paul Brion, Carolina Brito, Jacques Brouard, Emilie Catherinot, Olivia Chandesris, Sarah Cohen-Beaussant, Hélène Coignard-Biehler, Laurence Costes, Louis-Jean Couderc, Gérard Couillault, Virginie Courteille, Elodie Curlier, Geneviève de Saint Basile, François Demeocq, Nathalie de Vergnes, Catherine Devoldere, Anne Deville, Jean Donadieu, Eric Dore, Fabienne Dulieu, Isabelle Durieu, Christine Edan, Natacha Entz Werle, Claire Fieschi, Fanny Fouyssac, Pierre Frange, Vincent Gajdos, Lionel Galicier, Virginie Gandemer, Martine Gardembas, Catherine Gaud, Bernard Grosbois, Gaelle Guillerm, Eric Hachulla, Mohamed Hamidou, Sébastien Héritier, Olivier Hermine, Cyrille Hoarau, Bruno Hoen, Arnaud Hot, Sébastien Humbert, Arnaud Jaccard, Serge Jacquot, Rolland Jaussaud, Pierre-Yves Jeandel, Eric Jeziorski, Kamila Kebaili, Anne-Sophie Korganow, Philippe Labrune, Olivier Lambotte, Fanny Lanternier, Claire Larroche, Alain Le Quellec, Emmanuelle Le Moigne, Vincent Le Moing, Yvon Lebranchu, Marc Lecuit, Guillaume Lefevre, Richard Lemal, Philippe Le Moine, Valérie Li Thiao Te, Olivier Lortholary, Patrick Lutz, Aude Magerus-Chatinet, Marion Malphettes, Aude Marie-Cardine, Nicolas Martin Silva, Agathe Masseau, Christian Massot, Françoise Mazingue, Etienne Merlin, Gérard Michel, Frédéric Millot, Odile Minckes, Béatrice Monlibert, Fabrice Monpoux, Despina Moshous, Luc Mouthon, Martine Munzer, Bénédicte Neven, Raphaëlle Nove-Josserand, Eric Oksenhendler, Marie Ouachée-Chardin, Anne Pagnier, Jean-Louis Pasquali, Marlène Pasquet, Isabelle Pellier, Yves Perel, Antoinette Perlat, Capucine Picard, Christophe Piguet, Dominique Plantaz, Pierre Quartier, Frédéric Rieux-Laucat, Pascal Roblot, Pierre-Marie Roger, Pierre-Simon Rohrlich, Bruno Royer, Valéry Salle, Françoise Sarrot-Reynauld, Amélie Servettaz, Jean-Louis Stephan, Nicolas Schleinitz, Felipe Suarez, Laure Swiader, Sophie Taque, Caroline Thomas, Olivier Tournilhac, Caroline Thumerelle, Jean-Pierre Vannier, Jean-François Viallard
Publikováno v:
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, 2017, 140 (5), pp.1388-1393.e8. ⟨10.1016/j.jaci.2016.12.978⟩
Journal of Allergy and Clinical Immunology, Elsevier, 2017, 140 (5), pp.1388-1393.e8. ⟨10.1016/j.jaci.2016.12.978⟩
Journal of Allergy and Clinical Immunology, 2017, 140 (5), pp.1388-1393.e8. ⟨10.1016/j.jaci.2016.12.978⟩
Journal of Allergy and Clinical Immunology, Elsevier, 2017, 140 (5), pp.1388-1393.e8. ⟨10.1016/j.jaci.2016.12.978⟩
International audience; BACKGROUND:Primary immunodeficiencies (PIDs) are inherited diseases associated with a considerable increase in susceptibility to infections. It is known that PIDs can also predispose to cancer and immune diseases, including al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3112fd8ca76362c69ab2a291dc8a46
https://doi.org/10.1016/j.jaci.2016.12.978
https://doi.org/10.1016/j.jaci.2016.12.978
Publikováno v:
Medecine sciences : M/S. 24(5)
Fifty years ago, the first identification of a non Mendelian genetic contribution to the development of a common infectious disease, i.e. the association between malaria and sickle-cell trait, was shown using a supervised approach which tests a limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b65fde63dfda5d8bc65f3d7d836c9b34
https://pubmed.ncbi.nlm.nih.gov/18466726
https://pubmed.ncbi.nlm.nih.gov/18466726
Autor:
Vinicius M Fava, Monica Dallmann-Sauer, Marianna Orlova, Wilian Correa-Macedo, Nguyen Van Thuc, Vu Hong Thai, Alexandre Alcaïs, Laurent Abel, Aurélie Cobat, Erwin Schurr
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 12, p e0010029 (2021)
Leprosy is the second most prevalent mycobacterial disease globally. Despite the existence of an effective therapy, leprosy incidence has consistently remained above 200,000 cases per year since 2010. Numerous host genetic factors have been identifie
Externí odkaz:
https://doaj.org/article/084d0a397c8542769f79c1fd1fb72f27
Autor:
Jocelyn Quistrebert, Marianna Orlova, Gaspard Kerner, Le Thi Ton, Nguyễn Trong Luong, Nguyễn Thanh Danh, Quentin B Vincent, Fabienne Jabot-Hanin, Yoann Seeleuthner, Jacinta Bustamante, Stéphanie Boisson-Dupuis, Nguyen Thu Huong, Nguyen Ngoc Ba, Jean-Laurent Casanova, Christophe Delacourt, Eileen G Hoal, Alexandre Alcaïs, Vu Hong Thai, Lai The Thành, Laurent Abel, Erwin Schurr, Aurélie Cobat
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009392 (2021)
The natural history of tuberculosis (TB) is characterized by a large inter-individual outcome variability after exposure to Mycobacterium tuberculosis. Specifically, some highly exposed individuals remain resistant to M. tuberculosis infection, as in
Externí odkaz:
https://doaj.org/article/4f7beee9588e480d8337e49640f11266
Autor:
Monica Dallmann-Sauer, Vinicius M Fava, Chaïma Gzara, Marianna Orlova, Nguyen Van Thuc, Vu Hong Thai, Alexandre Alcaïs, Laurent Abel, Aurélie Cobat, Erwin Schurr
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008818 (2020)
Leprosy is a chronic disease caused by Mycobacterium leprae. Worldwide, more than 200,000 new patients are affected by leprosy annually, making it the second most common mycobacterial disease after tuberculosis. The MHC/HLA region has been consistent
Externí odkaz:
https://doaj.org/article/9a062af1f998473d99cbcb8dc8fe7f2f
Autor:
Chaima Gzara, Monica Dallmann-Sauer, Marianna Orlova, Nguyen Van Thuc, Vu Hong Thai, Vinicius M Fava, Marie-Thérèse Bihoreau, Anne Boland, Laurent Abel, Alexandre Alcaïs, Erwin Schurr, Aurélie Cobat
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008565 (2020)
Leprosy is a chronic infectious disease of the skin and peripheral nerves with a strong genetic predisposition. Recent genome-wide approaches have identified numerous common variants associated with leprosy, almost all in the Chinese population. We c
Externí odkaz:
https://doaj.org/article/cbc174f2581440d980692f23d6e3d9e5