Výsledky vyhledávání - "Alexandre A Steiner"

Akademický článek

Neural substrate of cold-seeking behavior in endotoxin shock.

Autor: Maria C Almeida, Alexandre A Steiner, Luiz G S Branco, Andrej A Romanovsky

Publikováno v: PLoS ONE, Vol 1, p e1 (2006)

Systemic inflammation is a leading cause of hospital death. Mild systemic inflammation is accompanied by warmth-seeking behavior (and fever), whereas severe inflammation is associated with cold-seeking behavior (and hypothermia). Both behaviors are a

Externí odkaz: https://doaj.org/article/86f9dfe04f0640878cca7c3625eebf3c

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Akademický článek

Cellular and molecular bases of the initiation of fever.

Autor: Alexandre A Steiner, Andrei I Ivanov, Jordi Serrats, Hiroshi Hosokawa, Allison N Phayre, Jared R Robbins, Jennifer L Roberts, Shigeo Kobayashi, Kiyoshi Matsumura, Paul E Sawchenko, Andrej A Romanovsky

Publikováno v: PLoS Biology, Vol 4, Iss 9, p e284 (2006)

All phases of lipopolysaccharide (LPS)-induced fever are mediated by prostaglandin (PG) E2. It is known that the second febrile phase (which starts at approximately 1.5 h post-LPS) and subsequent phases are mediated by PGE2 that originated in endothe

Externí odkaz: https://doaj.org/article/9de30b9a4eb44907b2d4085fa8e27d8a

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The neural pathway of the hyperthermic response to antagonists of the transient receptor potential vanilloid-1 channel

Autor: Andras Garami, Alexandre A. Steiner, Eszter Pakai, Samuel P. Wanner, M. Camila Almeida, Patrik Keringer, Daniela L. Oliveira, Kazuhiro Nakamura, Shaun F. Morrison, Andrej A. Romanovsky

Publikováno v: Temperature. 10:136-154

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34f73d6c5f98c393e2644d75be3afc18
https://doi.org/10.1080/23328940.2023.2171671

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Autoregulation of blood flow drives early hypotension in a rat model of systemic inflammation induced by bacterial lipopolysaccharide

Autor: Eduardo H Moretti, Abner C Rodrigues, Bruno V Marques, Leonardo T Totola, Caroline B Ferreira, Camila F Brito, Caroline M Matos, Filipe A da Silva, Robson A S Santos, Luciana B Lopes, Thiago S Moreira, Eliana H Akamine, Luiz A Baccala, André Fujita, Alexandre A Steiner

Publikováno v: PNAS Nexus. 2

Uncontrolled vasodilation is known to account for hypotension in the advanced stages of sepsis and other systemic inflammatory conditions, but the mechanisms of hypotension in earlier stages of such conditions are not clear. By monitoring hemodynamic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29816cf3bcff0a2cfc5f67e0ba1ce087
https://doi.org/10.1093/pnasnexus/pgad014

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Futile cycle of β-oxidation and de novo lipogenesis are associated with essential fatty acids depletion in lipoatrophy

Autor: Adriano B. Chaves-Filho, Albert S. Peixoto, Érique Castro, Tiago E. Oliveira, Luiz A. Perandini, Rafael J. Moreira, Railmara P. da Silva, Beatriz P. da Silva, Eduardo H. Moretti, Alexandre A. Steiner, Sayuri Miyamoto, Marcos Y. Yoshinaga, William T. Festuccia

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Total absence of adipose tissue (lipoatrophy) is associated with the development of severe metabolic disorders including hepatomegaly and fatty liver. Here, we sought to investigate the impact of severe lipoatrophy induced by deletion of peroxisome p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5997c6ffa3fab709aeeb64bdaa4eab08

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Naturally occurring hypothermia promotes survival in severe anaphylaxis

Autor: Alexandre A. Steiner, Ricardo Wesley Alberca, E. Moretti, Eliane Gomes, Momtchilo Russo

Publikováno v: Immunology Letters. 237:27-32

Although hypothermia has received substantial attention as an indicator of severity in anaphylaxis, it has been neglected from the perspective of whether it could act as a disease-modifying factor in this condition. Here, the impact of naturally occu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90013bbe3cc19fb57ad4f88a50ec5830
https://doi.org/10.1016/j.imlet.2021.07.002

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Hyaluronic acid nanoemulsions improve piplartine cytotoxicity in 2D and 3D breast cancer models and reduce tumor development after intraductal administration

Autor: Vanessa F.C. Dartora, Giovanna C. Salata, Julia S. Passos, Paola C. Branco, Edilberto Silveira, Alexandre A. Steiner, Leticia V. Costa-Lotufo, Luciana B. Lopes

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Nanoemulsions modified with chitosan (NE-Q) or hyaluronic acid (NE-HA), developed for intraductal administration of piplartine (piperlongumine) and local breast cancer treatment, were evaluated for cytotoxic effects in vitro in 2D and 3D breast cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bb41eb857b2e3b4baeda52744e7c63
https://pubmed.ncbi.nlm.nih.gov/35907458

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Opinions and Management of Hypothermic Sepsis: Results from an Online Survey

Autor: Janneke Horn, Alexandre A. Steiner, Nicole P. Juffermans, Ineke Pelleboer, Marcus J. Schultz, Maryse A. Wiewel, Matthew B.A. Harmon

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Hypothermia is associated with high mortality in sepsis, but it is now recognized that this association may simply reflect its higher prevalence in sicker patients. Furthermore, there is evidence to suggest that hypothermia may not represent a dysfun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e6105f3bc6fcfc72bb39075574a89e
https://doi.org/10.1089/ther.2019.0002

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