Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alexandre A Germanos"'
Autor:
Alexandre A Germanos, Sonali Arora, Ye Zheng, Erica T Goddard, Ilsa M Coleman, Anson T Ku, Scott Wilkinson, Hanbing Song, Nicholas J Brady, Robert A Amezquita, Michael Zager, Annalysa Long, Yu Chi Yang, Jason H Bielas, Raphael Gottardo, David S Rickman, Franklin W Huang, Cyrus M Ghajar, Peter S Nelson, Adam G Sowalsky, Manu Setty, Andrew C Hsieh
Publikováno v:
eLife, Vol 11 (2022)
Advanced prostate malignancies are a leading cause of cancer-related deaths in men, in large part due to our incomplete understanding of cellular drivers of disease progression. We investigate prostate cancer cell dynamics at single-cell resolution f
Externí odkaz:
https://doaj.org/article/df92bed0fdd1409a988b59a78b4ffbca
Autor:
Marie Y Davis, Kien Trinh, Ruth E Thomas, Selina Yu, Alexandre A Germanos, Brittany N Whitley, Sergio Pablo Sardi, Thomas J Montine, Leo J Pallanck
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005944 (2016)
Mutations in the glucosidase, beta, acid (GBA1) gene cause Gaucher's disease, and are the most common genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB) excluding variants of low penetrance. Because α-synuclein-cont
Externí odkaz:
https://doaj.org/article/3fb37e6949374aa09f6955f77c9a395e
Autor:
Alexandre A Germanos, Sonali Arora, Ye Zheng, Erica T Goddard, Ilsa M Coleman, Anson T Ku, Scott Wilkinson, Hanbing Song, Nicholas J Brady, Robert A Amezquita, Michael Zager, Annalysa Long, Yu Chi Yang, Jason H Bielas, Raphael Gottardo, David S Rickman, Franklin W Huang, Cyrus M Ghajar, Peter S Nelson, Adam G Sowalsky, Manu Setty, Andrew C Hsieh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f4bfb2220e32e7121b164ee228d7fc3
https://doi.org/10.7554/elife.79076.sa2
https://doi.org/10.7554/elife.79076.sa2
Autor:
Alexandre A. Germanos, Sonali Arora, Ye Zheng, Erica T. Goddard, Ilsa M. Coleman, Anson T. Ku, Scott Wilkinson, Robert A. Amezquita, Michael Zager, Annalysa Long, Yu Chi Yang, Jason H. Bielas, Raphael Gottardo, Cyrus M. Ghajar, Peter S. Nelson, Adam G. Sowalsky, Manu Setty, Andrew C. Hsieh
SummaryAdvanced prostate malignancies are a leading cause of cancer-related deaths in men, in large part due to our incomplete understanding of cellular drivers of disease progression. We investigated prostate cancer cell dynamics at single-cell reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::585809df8017aebd0426274fec2c7f71
https://doi.org/10.1101/2022.03.02.482711
https://doi.org/10.1101/2022.03.02.482711
Autor:
Yu Chen, Kalyan Banda, Ilsa Coleman, Peter S. Nelson, Asha Goodman, Sonali Arora, Sujata Jana, Jessie L. Horn, William R. Hardin, Yuzhen Liu, Eva Corey, Andrew C. Hsieh, Brett S. Carver, Yiting Lim, Robin Tharakan, Lexiaochuan Wen, Stephen R. Plymate, Yu C. Yang, Slobodan Beronja, Alexandre A. Germanos, Smitha P. S. Pillai, Elise Y. Cai, Colm Morrissey, Takuma Uo
Publikováno v:
Translational Cancer Research
Science Translational Medicine
Science Translational Medicine
The androgen receptor (AR) is a driver of cellular differentiation and prostate cancer development. An extensive body of work has linked these normal and aberrant cellular processes to mRNA transcription, however, the extent to which AR regulates pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf0c02313474c0163d2bf6a8e48740f
https://europepmc.org/articles/PMC6746573/
https://europepmc.org/articles/PMC6746573/
Autor:
Megan Kufeld, Madeline Larkin, Samantha L. Schuster, Slobodan Beronja, Andrew C. Hsieh, Alexandre A. Germanos, Sonali Arora, Elise Y. Cai
Publikováno v:
Cell Stem Cell
Summary Human skin tolerates a surprisingly high burden of oncogenic lesions. Although adult epidermis can suppress the expansion of individual mutant clones, the mechanisms behind tolerance to oncogene activation across broader regions of tissue are
Autor:
Brittany N. Whitley, Sergio Pablo Sardi, Kien Trinh, Marie Y. Davis, Leo J. Pallanck, Selina Yu, Alexandre A. Germanos, Thomas J. Montine, Ruth E. Thomas
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005944 (2016)
PLoS Genetics
PLoS Genetics
Mutations in the glucosidase, beta, acid (GBA1) gene cause Gaucher’s disease, and are the most common genetic risk factor for Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) excluding variants of low penetrance. Because α-synuclein-
Autor:
Luisa Matos do Canto, Alexandre A. Germanos, Osama E. Rahma, Mauricio Burotto, Bassem R. Haddad, John L. Marshall
Publikováno v:
World Journal of Gastrointestinal Oncology. 5:198
We are reporting on a colorectal cancer patient with the longest disease-free interval ever published, where chromosomal microarray analysis was used to confirm the link between the primary and metastatic lesions. This rare case reports on a patient