Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Alexandre, Perrier"'
Autor:
Lionel Michaux, Alexandre Perrier, Camille Mehlman, Hussa Alshehhi, Antonin Dubois, Roger Lacave, Florence Coulet, Jacques Cadranel, Vincent Fallet
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionALK tyrosine kinase inhibitors (ALK TKIs) have improved prognosis in ALK-rearranged (ALK+) non-small-cell lung cancer (NSCLC). However, drug resistance mechanisms occur inevitably during the course of treatment leading to disease progress
Externí odkaz:
https://doaj.org/article/06fd295534f1460995506172ad4190f9
Autor:
Alexandre, Perrier
We explain how to generalize Lazzarini's structural Theorem from [Laz11] to the case of curves with boundary on a given Lagrangian immersion. As a consequence of this result, we show that we can compute Floer homology with time-independent almost com
Externí odkaz:
http://arxiv.org/abs/1808.01849
Autor:
Mathilde Pacault, Camille Verebi, Magali Champion, Lucie Orhant, Alexandre Perrier, Emmanuelle Girodon, France Leturcq, Dominique Vidaud, Claude Férec, Thierry Bienvenu, Romain Daveau, Juliette Nectoux
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0280976 (2023)
Non-invasive prenatal diagnosis of single-gene disorders (SGD-NIPD) has been widely accepted, but is mostly limited to the exclusion of either paternal or de novo mutations. Indeed, it is still difficult to infer the inheritance of the maternal allel
Externí odkaz:
https://doaj.org/article/924e81eb10694715866e532df5d26618
Autor:
Alexandre Perrier, Pierre-Yves Boelle, Yves Chrétien, Joseph Gligorov, Jean-Pierre Lotz, Didier Brault, Eva Comperat, Guillaume Lefèvre, Mathieu Boissan
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227356 (2020)
BACKGROUND:The transmembrane receptor tyrosine kinase HER2 is overexpressed in approximately 15% of breast tumors and correlates with poor clinical prognosis. Several treatments that target HER2 are approved for treatment of HER2-positive metastatic
Externí odkaz:
https://doaj.org/article/bf3795ccb7434f9bb8c0c7cd94d5f75a
Autor:
Roseline Vibert, Jasmine Hasnaoui, Alexandre Perrier, Alexandra Lefebvre, Chrystelle Colas, Marion Dhooge, Noémie Basset, Albain Chansavang, Camille Desseignes, Alex Duval, Solenne Farelly, Nadim Hamzaoui, Pierre Laurent-Puig, Julie Metras, Diane Moliere, Martine Muleris, Jeanne Netter, Mehdi Touat, Franck Bielle, Karim Labreche, Romain Nicolle, Géraldine Perkins, Mathilde Warcoin, Florence Coulet, Patrick R. Benusiglio
Publikováno v:
European Journal of Human Genetics.
Autor:
Mélanie Eyries, Olivier Ariste, Gaelle Legrand, Noémie Basset, Erell Guillerm, Alexandre Perrier, Caroline Duros, Odile Cohen-Haguenauer, Pierre de la Grange, Florence Coulet
Publikováno v:
European Journal of Human Genetics. 30:1187-1190
Despite routine analysis of a large panel of genes, pathogenic variants are only detected in approximately 20% of families with hereditary breast and/or ovarian cancer. Mobile element insertions (MEI) are known to cause genetic diseases in humans, bu
Autor:
Alexandre Perrier, Pierre Hainaut, Alexandre Guenoun, Dinh-Phong Nguyen, Pierre-Jean Lamy, Fabrice Guerber, Frédéric Troalen, Jérôme Alexandre Denis, Mathieu Boissan
Publikováno v:
Bulletin du Cancer. 109:170-184
Autor:
Alexandre Perrier, Pierre Hainaut, Pierre-Jean Lamy, Alexandre Guenoun, Dinh-Phong Nguyen, Fabrice Guerber, Frédéric Troalen, Jérôme Alexandre Denis, Mathieu Boissan
Publikováno v:
Bulletin du Cancer. 109:151-169
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 1061 (2020)
Immune checkpoint inhibitors (ICIs) have demonstrated to be highly efficient in treating solid tumors; however, many patients have limited benefits in terms of response and survival. This rapidly led to the investigation of combination therapies to e
Externí odkaz:
https://doaj.org/article/3bb0f7bf7c4d4142b9fa00ffa63ae57b
Autor:
Hélène Blons, Pierre Laurent-Puig, Laure Gibault, Françoise Le Pimpec-Barthes, Guillaume Beinse, Jean-Baptiste Oudart, Thomas Denize, Jean-Baptiste Leclere, Simon Garinet, Cécile Badoual, Audrey Didelot, Alexandre Perrier, Antoine Legras
Publikováno v:
Br J Cancer
BACKGROUND: Patients with non-small cell lung cancer (NSCLC) receiving curative surgery have a risk of relapse, and adjuvant treatments only translate into a 5% increase in 5-year survival. We assessed the clinical significance of epithelial–mesenc