Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Alexandre, Kreisler"'
Publikováno v:
Toxins, Vol 16, Iss 10, p 439 (2024)
Background: Cervical dystonia is widely understood to benefit from botulinum toxin injections. The injection practices may be influenced by specific factors, including the method of injection. Three main guidance methods can be used: palpation of ana
Externí odkaz:
https://doaj.org/article/fe4a893360b34a78bc3beebfa66ce8be
Autor:
Jean-Marc Taymans, Eugénie Mutez, William Sibran, Laurine Vandewynckel, Claire Deldycke, Séverine Bleuse, Antoine Marchand, Alessia Sarchione, Coline Leghay, Alexandre Kreisler, Clémence Simonin, James Koprich, Guillaume Baille, Luc Defebvre, Kathy Dujardin, Alain Destée, Marie-Christine Chartier-Harlin
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Expression or phosphorylation levels of leucine-rich repeat kinase 2 (LRRK2) and its Rab substrates have strong potential as disease or pharmacodynamic biomarkers. The main objective of this study is therefore to assess the LRRK2-Rab pathway
Externí odkaz:
https://doaj.org/article/b7e9bd2df83248dc86dcac1c9f1e4ea1
Publikováno v:
Tremor and Other Hyperkinetic Movements, Vol 9, Iss 0, Pp 1-7 (2019)
Background: Botulinum neurotoxin’s degree of effectiveness on upper limb tremor is subject to debate; although this treatment reduces the tremor’s amplitude, a clear functional benefit has not been demonstrated. The objective of this study was to
Externí odkaz:
https://doaj.org/article/748e9696f095419bb17e8a79d4ca7b69
Autor:
David Amarantini, Isabelle Rieu, Giovanni Castelnovo, Frédérique Fluchère, Chloé Laurencin, Bertrand Degos, Aurélia Poujois, Alexandre Kreisler, Sophie Sangla, Mélissa Tir, Isabelle Benatru, Geneviève Blanchet-Fourcade, Dominique Guehl, Dominique Gayraud, Laurent Tatu, Christine Tranchant, Franck Durif, Marion Simonetta-Moreau
Publikováno v:
Sensors, Vol 22, Iss 6, p 2385 (2022)
This study compares two methods to quantify the amplitude and frequency of head movements in patients with head tremor: one based on video-based motion analysis, and the other using a miniature wireless inertial magnetic motion unit (IMMU). Concomita
Externí odkaz:
https://doaj.org/article/2293b07df69241869cf19af8a8d54e07
Autor:
Jean-Marc Taymans, Eugenie Mutez, William Sibran, Laurine Vandewynckel, Claire Deldycke, Séverine Bleuse, Antoine Marchand, Alessia Sarchione, Alexandre Kreisler, Clémence Simonin, James Koprich, Guillaume Baille, Luc Defebvre, Kathy Dujardin, Alain Destée, Marie-Christine Chartier-Harlin
Levels of expression or of phosphorylation of leucine-rich repeat kinase 2 (LRRK2) and its Rab substrates have the potential for use as disease or pharmacodynamic biomarkers. LRRK2 phosphorylation levels at the S910-S935-S955-S973 phosphosites are re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6988641738077811fa242321eb83e9b0
https://doi.org/10.21203/rs.3.rs-1677803/v1
https://doi.org/10.21203/rs.3.rs-1677803/v1
Publikováno v:
Journal of Neurology. 268:1894-1902
The col-cap concept encouraged neurologists to inject a large group of muscles in the treatment of cervical dystonia. This includes deep muscles such as the obliquus capitis inferior or the semispinalis capitis, and muscles close to vascular or neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b74b56afc03aa1d43174547a96a95fb
https://doi.org/10.1007/s00415-020-10365-w
https://doi.org/10.1007/s00415-020-10365-w
Autor:
Jarosław Sławek, Sanjay Pandey, Alexandre Kreisler, Artur Drużdż, Wolfgang H. Jost, Christian F Altmann, Bo Biering-Sørensen, Laurent Tatu
Publikováno v:
Journal of Neural Transmission. 127:45-50
Patients with cervical dystonia (CD) may present with head and/or neck movements in the coronal, sagittal or transverse plane. According to the Col-Cap concept, CD postures are classified in torti-, latero-, ante- and retrocollis/caput patterns. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6e28fb6c8d6886730145d2eb396775
https://doi.org/10.1007/s00702-019-02116-7
https://doi.org/10.1007/s00702-019-02116-7
Autor:
Alain Destée, Sabine Hilfiker, Elena Fdez, Thomas Comptdaer, Jean-Marc Taymans, Eugénie Mutez, Alexandre Kreisler, Belén Fernández, Laurine Vandewynckel, Marie-Christine Chartier-Harlin, Coline Leghay, Luc Defebvre, Séverine Bleuse, Clémence Simonin, Antonio Ordóñez
Publikováno v:
Biochemical Journal
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Leucine-rich repeat kinase 2 (LRRK2) is a promising therapeutic target for the treatment of Parkinson's disease (PD), and orally bioavailable, brain penetrant and highly potent LRRK2 kinase inhibitors are in early stages of clinical testing. Detectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2fc3c80cf37117df6143302332f9bb
https://doi.org/10.1042/bcj20190315
https://doi.org/10.1042/bcj20190315
Publikováno v:
Toxicon. 214:S34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30c80c5d991004324c3aed8b058e5149
https://doi.org/10.1016/j.toxicon.2021.11.077
https://doi.org/10.1016/j.toxicon.2021.11.077