Výsledky vyhledávání - "Alexandre, Ceroni"

Akademický článek

Angiotensin II, blood–brain barrier permeability, and microglia interplay during the transition from pre-to hypertensive phase in spontaneously hypertensive rats

Autor: Mariana Makuch-Martins, Camilla G. Vieira-Morais, Sany M. Perego, Adriana Ruggeri, Alexandre Ceroni, Lisete C. Michelini

Publikováno v: Frontiers in Physiology, Vol 15 (2024)

BackgroundHypertension is characterized by upregulation of the renin–angiotensin system, increased blood–brain barrier (BBB) permeability, microglia activation within autonomic nuclei, and an intense sympathoexcitation. There is no information on

Externí odkaz: https://doaj.org/article/c152a371ef94414ba0b419c0099ca5fb

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Akademický článek

Trained hypertensive rats exhibit decreased transcellular vesicle trafficking, increased tight junctions’ density, restored blood-brain barrier permeability and normalized autonomic control of the circulation

Autor: Vanessa B. Candido, Sany M. Perego, Alexandre Ceroni, Martin Metzger, Alison Colquhoun, Lisete C. Michelini

Publikováno v: Frontiers in Physiology, Vol 14 (2023)

Introduction: Chronic hypertension is accompanied by either blood-brain barrier (BBB) leakage and autonomic dysfunction. There is no consensus on the mechanism determining increased BBB permeability within autonomic areas. While some reports suggeste

Externí odkaz: https://doaj.org/article/83feaa3b87d14e28959124882dbc0d8c

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Akademický článek

Perfusion of Brain Preautonomic Areas in Hypertension: Compensatory Absence of Capillary Rarefaction and Protective Effects of Exercise Training

Autor: Maria Tereza Jordão, Alexandre Ceroni, Lisete C. Michelini

Publikováno v: Frontiers in Physiology, Vol 12 (2021)

Remodeling of capillary rarefaction and deleterious arteries are characteristic hallmarks of hypertension that are partially corrected by exercise training. In addition, experimental evidence showed capillary rarefaction within the brain cortex and r

Externí odkaz: https://doaj.org/article/91c7dec58fc9469ab3b71b1f66f35b7d

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Akademický článek

Histidine dipeptides are key regulators of excitation-contraction coupling in cardiac muscle: Evidence from a novel CARNS1 knockout rat model

Publikováno v: Redox Biology, Vol 44, Iss , Pp 102016- (2021)

Histidine-containing dipeptides (HCDs) are abundantly expressed in striated muscles. Although important properties have been ascribed to HCDs, including H+ buffering, regulation of Ca2+ transients and protection against oxidative stress, it remains u

Externí odkaz: https://doaj.org/article/a9598ad9e37346bba801d36e51ccf3f4

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Akademický článek

Activity-Dependent Neuroplastic Changes in Autonomic Circuitry Modulating Cardiovascular Control: The Essential Role of Baroreceptors and Chemoreceptors Signaling

Autor: Carla Rocha-Santos, Douglas Costa Braga, Alexandre Ceroni, Lisete C. Michelini

Publikováno v: Frontiers in Physiology, Vol 11 (2020)

Aerobic exercise training improves the autonomic control of the circulation. Emerging evidence has shown that exercise induces neuroplastic adaptive changes in preautonomic circuitry controlling sympathetic/parasympathetic outflow to heart and vessel

Externí odkaz: https://doaj.org/article/4555a243410c4928a7a9737b8536c4d1

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Akademický článek

Exercise training increases GAD65 expression, restores the depressed GABAA receptor function within the PVN and reduces sympathetic modulation in hypertension

Autor: Nilson C. Ferreira‐Junior, Adriana Ruggeri, Sebastião D. Silva Jr, Thais T. Zampieri, Alexandre Ceroni, Lisete C. Michelini

Publikováno v: Physiological Reports, Vol 7, Iss 13, Pp n/a-n/a (2019)

Abstract GABAergic inhibitory input within the paraventricular hypothalamic nucleus (PVN) plays a key role in restraining sympathetic outflow. Although experimental evidence has shown depressed GABAA receptor function plus sympathoexcitation in hyper

Externí odkaz: https://doaj.org/article/8e215cb08c16422890142658279fcf6d

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Akademický článek

Maintenance of Blood-Brain Barrier Integrity in Hypertension: A Novel Benefit of Exercise Training for Autonomic Control

Autor: Leila Buttler, Maria T. Jordão, Matheus G. Fragas, Adriana Ruggeri, Alexandre Ceroni, Lisete C. Michelini

Publikováno v: Frontiers in Physiology, Vol 8 (2017)

The blood-brain barrier (BBB) is a complex multicellular structure acting as selective barrier controlling the transport of substances between these compartments. Accumulating evidence has shown that chronic hypertension is accompanied by BBB dysfunc

Externí odkaz: https://doaj.org/article/16e4ad7675e3435faa0734ea07f2c391

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Abstract 32: Exercise Training Corrects Blood-brain Barrier Dysfunction Within Preautonomic Areas Of Spontaneously Hypertensive Rats By Normalizing The Augmented Transcytosis

Autor: Alexandre Ceroni, Lisete Compagno Michelini, Vanessa Brito Candido, Alison Colquhoun

Publikováno v: Hypertension. 78

Introduction: Besides intense neuro-hormonal activation, hypertension is accompanied by blood-brain barrier (BBB) dysfunction within preautonomic areas and marked autonomic imbalance. We showed previously that exercise training (T) corrected both inc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca0943550503e22474dacb9bc38d8ec1
https://doi.org/10.1161/hyp.78.suppl_1.32

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Histidine dipeptides are key regulators of excitation-contraction coupling in cardiac muscle: Evidence from a novel CARNS1 knockout rat model

Publikováno v: Redox Biology, Vol 44, Iss, Pp 102016-(2021)
Redox Biology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07cad5c54ad58bb7ffb7082315846996
http://www.sciencedirect.com/science/article/pii/S2213231721001749

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Exercise training improves cardiovascular control in sinoaortic denervated SHR by reducing the elevated angiotensin II and augmenting angiotensin-(1−7) availability within autonomic and neuroendocrine PVN nuclei

Autor: Hiviny A. Raquel, Louisi A. Manica, Alexandre Ceroni, Lisete C. Michelini

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Previous studies have shown that baroreceptors- and chemoreceptors-denervated SHR exhibit impaired central autonomic circuitry and worsening of the cardiovascular function. It was also known that exercise training (T) ameliorates the autonomic contro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df870665ff7ac94816461568b15976c
https://doi.org/10.1016/j.peptides.2022.170798

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