Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Alexandre, Boissonnas"'
Autor:
Rebecca Fima, Sébastien Dussaud, Cheïma Benbida, Margault Blanchet, François Lanthiez, Lucie Poupel, Claudia Brambilla, Adélaïde Gélineau, Mattia Dessena, Marina Blanc, Cédric Lerévérend, Martine Moreau, Alexandre Boissonnas, Emmanuel L. Gautier, Thierry Huby
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Hypercholesterolemia is a major risk factor for atherosclerosis and associated cardiovascular diseases. The liver plays a key role in the regulation of plasma cholesterol levels and hosts a large population of tissue-resident macrophages kno
Externí odkaz:
https://doaj.org/article/89c899c16f044d8386a1726bcc726695
Autor:
Marion Blaize, Guillaume Thizy, Alexandre Boissonnas, Anaïs Portalier, Fanny Lanternier, Clémentine de La Porte des Vaux, Felipe Suarez, Marie-Elisabeth Bougnoux, Juliette Guitard, Arnaud Jabet, Nicolas Stocker, Abdelmalek Aoudjhane, Damien Roos-Weil, Arnaud Fekkar
Publikováno v:
International Journal of Infectious Diseases, Vol 142, Iss , Pp 107000- (2024)
Objectives: Ibrutinib, a first-generation covalent Bruton's tyrosine kinase inhibitor (BTKi) was found to be a risk factor for the occurrence of invasive fungal complications. Acalabrutinib is a second-generation covalent BTKi used to treat B-cell ma
Externí odkaz:
https://doaj.org/article/f390dee4838949199893535f4082b903
Autor:
Aitziber Buqué, Norma Bloy, Maria Perez-Lanzón, Kristina Iribarren, Juliette Humeau, Jonathan G. Pol, Sarah Levesque, Laura Mondragon, Takahiro Yamazaki, Ai Sato, Fernando Aranda, Sylvère Durand, Alexandre Boissonnas, Jitka Fucikova, Laura Senovilla, David Enot, Michal Hensler, Margerie Kremer, Gautier Stoll, Yang Hu, Chiara Massa, Silvia C. Formenti, Barbara Seliger, Olivier Elemento, Radek Spisek, Fabrice André, Laurence Zitvogel, Suzette Delaloge, Guido Kroemer, Lorenzo Galluzzi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Current preclinical models to investigate human HR + breast cancer progression and response to immunotherapy in vivo are limited. Here, the authors demonstrate that mammary tumours driven by a synthetic progestin combined with an oral carcinogen reca
Externí odkaz:
https://doaj.org/article/a7e37a6ac2cb4091b97dc956fd1c341a
Autor:
Behazine Combadière, Lucille Adam, Noëlline Guillou, Paul Quentric, Pierre Rosenbaum, Karim Dorgham, Olivia Bonduelle, Christophe Parizot, Delphine Sauce, Julien Mayaux, Charles-Edouard Luyt, Alexandre Boissonnas, Zahir Amoura, Valérie Pourcher, Makoto Miyara, Guy Gorochov, Amélie Guihot, Christophe Combadière
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundLymphopenia and the neutrophil/lymphocyte ratio may have prognostic value in COVID-19 severity.ObjectiveWe investigated neutrophil subsets and functions in blood and bronchoalveolar lavage (BAL) of COVID-19 patients on the basis of patients
Externí odkaz:
https://doaj.org/article/232415f65d5245ada82ed7530edfe7df
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In mice, monocytes (Mo) are conventionally described as CX3CR1low classical Mo (CMo) and CX3CR1high non-classical Mo (NCMo) based on the expression of EGFP in Cx3cr1+/EGFP mice and by analogy with human CX3CR1 expression. Although this terminology is
Externí odkaz:
https://doaj.org/article/b351eb5f4ef94cc6af5a882720483838
Autor:
Camille Baudesson de Chanville, Benjamin Glenn Chousterman, Pauline Hamon, Marie Laviron, Noelline Guillou, Pierre Louis Loyher, Aida Meghraoui-Kheddar, Sandrine Barthelemy, Philippe Deterre, Alexandre Boissonnas, Christophe Combadière
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Sepsis is characterized by a systemic inflammation that can cause an immune dysfunction, for which the underlying mechanisms are unclear. We investigated the impact of cecal ligature and puncture (CLP)-mediated polymicrobial sepsis on monocyte (Mo) m
Externí odkaz:
https://doaj.org/article/9c9ba8b250404d9d974fb9fbf78e5c30
Autor:
Damien Blez, Marion Blaize, Carole Soussain, Alexandre Boissonnas, Aïda Meghraoui-Kheddar, Natacha Menezes, Anaïs Portalier, Christophe Combadière, Véronique Leblond, David Ghez, Arnaud Fekkar
Publikováno v:
Haematologica, Vol 105, Iss 2 (2020)
The Bruton tyrosine kinase inhibitor ibrutinib has become a leading therapy against chronic lymphoid leukemia. Recently, ibrutinib has been associated with the occurrence of invasive fungal infections, in particular invasive aspergillosis. The mechan
Externí odkaz:
https://doaj.org/article/1c077324ae1042c4a725880996a0e2f9
Autor:
Aurélie Durand, Alexandra Audemard-Verger, Vincent Guichard, Raphaël Mattiuz, Arnaud Delpoux, Pauline Hamon, Nelly Bonilla, Matthieu Rivière, Jérôme Delon, Bruno Martin, Cédric Auffray, Alexandre Boissonnas, Bruno Lucas
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Non-circulating, tissue-resident T cells have been reported for non-lymphoid organs, but their characterization and regulation in secondary lymphoid organs (SLO) are still lacking. Here the authors show that age and microbiota both exert SLO-specific
Externí odkaz:
https://doaj.org/article/6817c7ab4e8648ea9360a32bfd190459
Autor:
Guilherme D. Melo, Sophie Goyard, Laurence Fiette, Alexandre Boissonnas, Christophe Combadiere, Gisele F. Machado, Paola Minoprio, Thierry Lang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Visceral leishmaniasis (VL) is a systemic disease with multifaceted clinical manifestations, including neurological signs, however, the involvement of the nervous system during VL is underestimated. Accordingly, we investigated both brain in
Externí odkaz:
https://doaj.org/article/89cd1e4323e7400da7d481be4d8b9c5f
Autor:
Marie Laviron, Alexandre Boissonnas
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Tumor-associated macrophages (TAM) represent the main immune cell population of the tumor microenvironment in most cancer. For decades, TAM have been the focus of intense investigation to understand how they modulate the tumor microenvironment and th
Externí odkaz:
https://doaj.org/article/9d04d75f1d0f4accb48c3923b05c8699