Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alexandra Zirk"'
Autor:
Julia Kirchheiner, Sabine Engelhardt, Jürgen Brockmöller, Stefan Viktor Vormfelde, Franziska Tuchen, Alexandra Zirk, Ingolf Meineke
Publikováno v:
Clinical Pharmacology & Therapeutics. 76:557-566
Introduction According to in vitro data, torsemide (INN, torasemide) is a substrate of the genetically polymorphic enzyme cytochrome P450 (CYP) 2C9, but the impact of CYP2C9 polymorphisms on torsemide pharmacokinetics and pharmacodynamics has not bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ddbba83143a73e6429f1aaab12bb6c
https://doi.org/10.1016/j.clpt.2004.08.024
https://doi.org/10.1016/j.clpt.2004.08.024
Autor:
Stefan Viktor Vormfelde, Leszek Wojnowski, Alexandra Zirk, Gerhard Burckhardt, Jürgen Brockmöller
Publikováno v:
Pharmacogenomics. 4:701-734
This review summarizes the current status of our knowledge about the role of pharmacogenetic variation in response to diuretics and suggests future research topics for the field. Genes with a role in the pharmacokinetics of most diuretics are renal d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5ce9bb2a3f1125533fad3e87465bd5
https://doi.org/10.1517/phgs.4.6.701.22817
https://doi.org/10.1517/phgs.4.6.701.22817
Publikováno v:
Journal of Oral and Maxillofacial Surgery. 56:440-443
Purpose: This retrospective study evaluated data pertaining to the history, symptoms, treatment, and prognosis of a series of patients treated for acinic cell carcinoma (ACC). Patients and Methods: Data were based on the records of 35 patients. Follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03253d434ec86c00806e6eb1441615d2
https://doi.org/10.1016/s0278-2391(98)90708-x
https://doi.org/10.1016/s0278-2391(98)90708-x
Autor:
Stefan Viktor, Vormfelde, Sabine, Engelhardt, Alexandra, Zirk, Ingolf, Meineke, Franziska, Tuchen, Julia, Kirchheiner, Jürgen, Brockmöller
Publikováno v:
Clinical pharmacology and therapeutics. 76(6)
According to in vitro data, torsemide (INN, torasemide) is a substrate of the genetically polymorphic enzyme cytochrome P450 (CYP) 2C9, but the impact of CYP2C9 polymorphisms on torsemide pharmacokinetics and pharmacodynamics has not been studied in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ff98148e7baa40aa5b8a5b30ff13224
https://pubmed.ncbi.nlm.nih.gov/15592327
https://pubmed.ncbi.nlm.nih.gov/15592327
Publikováno v:
Clinical Pharmacology & Therapeutics. 75:P66
According to in-vitro data, torasemide is a substrate of the genetically polymorphic enzyme CYP2C9 but the impact of CYP2C9 polymorphisms on torasemide pharmacodynamics has not yet been studied. 86 healthy volunteers received a single oral dose of 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d8a2c8e8880fb792f783aa7fe0324e0
https://doi.org/10.1016/j.clpt.2003.11.249
https://doi.org/10.1016/j.clpt.2003.11.249
Autor:
Stefan Viktor Vormfelde, Alexandra Zirk, F. Tuchen, M. Torn, J. Westermann, J. Brockmöller, Mohammad R. Toliat
Publikováno v:
Clinical Pharmacology & Therapeutics. 75:P63
Objective Genetic variability in pharmacokinetics and pharmacodynamics of diuretics is incompletely studied. We compared the extent of variability in different loop diuretics and determined to what extent this is influenced by polymorphisms in candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69fb46f9f3839b00cc80b9f6ca57bdd8
https://doi.org/10.1016/j.clpt.2003.11.239
https://doi.org/10.1016/j.clpt.2003.11.239