Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alexandra Zielinski"'
Autor:
Sergey A. Dyshlovoy, Wael Y. Mansour, Natalia A. Ramm, Jessica Hauschild, Maxim E. Zhidkov, Malte Kriegs, Alexandra Zielinski, Konstantin Hoffer, Tobias Busenbender, Ksenia A. Glumakova, Pavel V. Spirin, Vladimir S. Prassolov, Derya Tilki, Markus Graefen, Carsten Bokemeyer, Gunhild von Amsberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Fascaplysin is a red cytotoxic pigment with anticancer properties isolated from the marine sponge Fascaplysinopsis sp. Recently, structure–activity relationship analysis reported by our group suggested that selective cytotoxicity of fascap
Externí odkaz:
https://doaj.org/article/df82a4dc141245f18a09fe909aa98ef5
Autor:
Gunhild von Amsberg, Mirjam Zilles, Wael Mansour, Philipp Gild, Winfried Alsdorf, Moritz Kaune, Lukas Böckelmann, Jessica Hauschild, Christoph Krisp, Tina Rohlfing, Ceren Saygi, Malik Alawi, Alexandra Zielinski, Claudia Langebrake, Su Jung Oh-Hohenhorst, Sven Perner, Derya Tilki, Hartmut Schlüter, Markus Graefen, Sergey A. Dyshlovoy, Carsten Bokemeyer
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14948
Significant progress has been achieved in the treatment of metastatic castration-resistant prostate cancer (mCRPC). However, results in patients with aggressive variant prostate cancer (AVPC) have been disappointing. Here, we report retrospectively c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3908f98ffeab745db9d4c3fa68240db7
https://pubmed.ncbi.nlm.nih.gov/36499277
https://pubmed.ncbi.nlm.nih.gov/36499277
Autor:
Sandra, Classen, Elena, Rahlf, Johannes, Jungwirth, Nina, Albers, Luca Philipp, Hebestreit, Alexandra, Zielinski, Lena, Poole, Marco, Groth, Philipp, Koch, Thomas, Liehr, Stefanie, Kankel, Nils, Cordes, Cordula, Petersen, Kai, Rothkamm, Helmut, Pospiech, Kerstin, Borgmann
Publikováno v:
International journal of molecular sciences. 23(21)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b4c8170cbd7e3b236bb16244c4191a1
https://pubmed.ncbi.nlm.nih.gov/36362151
https://pubmed.ncbi.nlm.nih.gov/36362151
Autor:
Albert Job, Marina Tatura, Cora Schäfer, Veronika Lutz, Hanna Schneider, Brigitte Lankat-Buttgereit, Alexandra Zielinski, Kerstin Borgmann, Christian Bauer, Thomas M. Gress, Malte Buchholz, Eike Gallmeier
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Inhibition of the kinase ATR, a central regulator of the DNA damage response, eliminates subsets of cancer cells in certain tumors. As previously shown, this is at least partly attributable to synthetic lethal interactions between ATR and POLD1, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::0dac2d9915d77e4af9982dab287299c7
http://link.springer.com/article/10.1038/s41598-020-76033-1
http://link.springer.com/article/10.1038/s41598-020-76033-1
Autor:
Sandra Classen, Elena Rahlf, Johannes Jungwirth, Nina Albers, Luca Philipp Hebestreit, Alexandra Zielinski, Lena Poole, Marco Groth, Philipp Koch, Thomas Liehr, Stefanie Kankel, Nils Cordes, Cordula Petersen, Kai Rothkamm, Helmut Pospiech, Kerstin Borgmann
Publikováno v:
Cancers 23(2022)21, 13363
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13363
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13363
BRCA1 is a well-known breast cancer risk gene, involved in DNA damage repair via homologous recombination (HR) and replication fork protection. Therapy resistance was linked to loss and amplification of the BRCA1 gene causing inferior survival of bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6336d537ed98414e15d07389733ae430
http://urn.fi/urn:nbn:fi-fe2023063068689
http://urn.fi/urn:nbn:fi-fe2023063068689
Autor:
Ioan T. Bold, Alexandra Zielinski, Ann-Kathrin Specht, Adrian Münscher, Till S. Clauditz, Conrad Droste, Kerstin Borgmann, Felix Meyer, Stefan Werner, Kai Rothkamm, Cordula Petersen
Publikováno v:
Cancers, Vol 13, Iss 1194, p 1194 (2021)
Cancers
Volume 13
Issue 6
Cancers
Volume 13
Issue 6
Aneuploidy is a consequence of chromosomal instability (CIN) that affects prognosis. Gene expression levels associated with aneuploidy provide insight into the molecular mechanisms underlying CIN. Based on the gene signature whose expression was cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193d7fde46e43751a3a87d442e68b281
https://www.mdpi.com/2072-6694/13/6/1194
https://www.mdpi.com/2072-6694/13/6/1194
Autor:
Sandra Classen, Alexandra Zielinski, Kerstin Borgmann, Harriet Wikman, Felix Meyer, Ann Christin Parplys, Cordula Petersen, Johanna Rieckhoff, Kai Rothkamm, Britta Riepen
Publikováno v:
Cancers
Volume 12
Issue 10
Cancers, Vol 12, Iss 2809, p 2809 (2020)
Volume 12
Issue 10
Cancers, Vol 12, Iss 2809, p 2809 (2020)
Simple Summary The poor prognosis of patients with TNBC have fostered a major effort to identify more patients who would benefit from targeted therapies. Here we recognize PTEN as a potential CIN-causing gene in TNBC and consider PTEN-deficient TNBC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682d5bab0c49096f7900e8bce9c2072e
Autor:
Anastassia Löser, Christoph Oing, Carsten Bokemeyer, Hartwig Huland, Wael Y. Mansour, Su Jung Oh-Hohenhorst, Stefanie Meien, Cordula Petersen, Susanne Burdak-Rothkamm, Derya Tilki, Sally Mutiara, Sabrina Köcher, Kai Rothkamm, Alexandra Zielinski, Mohamed E Elsesy, Rudolf Schwarz
Publikováno v:
Cancers, Vol 12, Iss 2467, p 2467 (2020)
CANCERS
Cancers
Volume 12
Issue 9
CANCERS
Cancers
Volume 12
Issue 9
(1) Background: The combination of the first-generation antiandrogens and radiotherapy (RT) has been studied extensively in the clinical setting of prostate cancer (PCa). Here, we evaluated the potential radiosensitizing effect of the second-generati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8c3d6f3d147206ce9c58cec9dd762d
https://www.mdpi.com/2072-6694/12/9/2467
https://www.mdpi.com/2072-6694/12/9/2467
Autor:
Govind M. Pai, Kristin Ludwig, Zhao-Qi Wang, Alexandra Zielinski, Dennis Koalick, Kerstin Borgmann, Ignacio Rubio, Helmut Pospiech
Publikováno v:
Oncotarget
OncoTarget, 7(51): 85365–380
OncoTarget, 7(51): 85365–380
// Govind M. Pai 1 , Alexandra Zielinski 2 , Dennis Koalick 3 , Kristin Ludwig 1 , Zhao-Qi Wang 3 , Kerstin Borgmann 2 , Helmut Pospiech 3, 4 , Ignacio Rubio 1 1 Institute of Molecular Cell Biology, Center for Molecular Biomedicine, University Hospit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b7f38062bf540d0430c1700061132b
http://europepmc.org/articles/PMC5356742
http://europepmc.org/articles/PMC5356742
Autor:
Helmut Pospiech, Florian Kraft, Alexandra Zielinski, Anja Weise, Kerstin Borgmann, Bernhard Schlott, Kristin Mrasek, Franziska Foertsch, Anna Szambowska, Christian Melle, Frank Grosse
The repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) is an essential process in maintenance of chromosomal stability. A key player of HR is the strand exchange factor RAD51 whose assembly at sites of DNA damage is tightly re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb72daa6e581c0d3f82cc8522da561b
https://europepmc.org/articles/PMC5053559/
https://europepmc.org/articles/PMC5053559/