Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alexandra Z. Andreou"'
Linking translation factor conformational dynamics with translation efficiencies and gene expression
Autor:
Linda Krause, Anirban Chakraborty, Florian Willing, Vaibhav Mhaindarkar, Alexandra Z. Andreou, Dagmar Klostermeier
Publikováno v:
Biophysical Journal. 122:317a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaa7ea97ded186612e3d001fcdb802a3
https://doi.org/10.1016/j.bpj.2022.11.1778
https://doi.org/10.1016/j.bpj.2022.11.1778
Linking translation factor conformational dynamics with translation efficiencies and gene expression
Publikováno v:
Biophysical Journal. 121:338a-339a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55cbcfe7c1c6f10b0a24c125930cddd1
https://doi.org/10.1016/j.bpj.2021.11.1080
https://doi.org/10.1016/j.bpj.2021.11.1080
Publikováno v:
Nucleic Acids Research
Eukaryotic translation initiation requires unwinding of secondary structures in the 5′-untranslated region of mRNA. The DEAD-box helicase eIF4A is thought to unwind structural elements in the 5′-UTR in conjunction with eIF4G and eIF4B. Both facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487f44a836cfabdf190cb11a3492f199
https://doi.org/10.1093/nar/gkz254
https://doi.org/10.1093/nar/gkz254
Publikováno v:
Epigenetics
The presence of 5-hydroxymethyl cytosine in DNA has been previously associated with ageing. Using in silico analysis of normal liver samples we presently observed that in 5-hydroxymethyl cytosine sequences, DNA methylation is dependent on the co-pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0832e1e1f593e69f8c1b6d447e4db8e
https://pubmed.ncbi.nlm.nih.gov/32752914
https://pubmed.ncbi.nlm.nih.gov/32752914
Autor:
Elisavet Georgiou, Alexandra Z. Andreou, Leda Kovatsi, Andigoni Malousi, Sofia Kouidou, Georgios Tzimagiorgis
Publikováno v:
Epigenetics
Horvath’s epigenetic clock consists of 353 CpGs whose methylation levels can accurately predict the age of individuals. Using bioinformatics analysis, we investigated the conformation, energy characteristics and presence of tentative splice sites o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120496878cb0a041d8354001d334b576
https://doi.org/10.1080/15592294.2018.1514232
https://doi.org/10.1080/15592294.2018.1514232
Publikováno v:
RNA Biology. 14:113-123
Eukaryotic translation initiation starts with binding of the eIF4F complex to the 5′-m7G cap of the mRNA. Recruitment of the 43S pre-initiation complex (PIC), formed by the 40S ribosomal subunit and other translation initiation factors, leads to fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd01cb55e042134fa3731f8ce2df0be
https://doi.org/10.1080/15476286.2016.1259782
https://doi.org/10.1080/15476286.2016.1259782
Publikováno v:
Biophysical Journal. 118:546a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb93f6b8552bc2ff5c7109436f7b377d
https://doi.org/10.1016/j.bpj.2019.11.2986
https://doi.org/10.1016/j.bpj.2019.11.2986
Publikováno v:
RNA Biology. 10:19-32
DEAD-box helicases catalyze the ATP-dependent unwinding of RNA duplexes. They share a helicase core formed by two RecA-like domains that carries a set of conserved motifs contributing to ATP binding and hydrolysis, RNA binding and duplex unwinding. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b34caf7d1370fb0b37cb3b44bd68a6
https://doi.org/10.4161/rna.21966
https://doi.org/10.4161/rna.21966
Autor:
Dagmar Klostermeier, Katherine E. Sloan, Mira Prior, Henning Urlaub, Philipp Hackert, Jörg Enderlein, Annika U. Heininger, Reinhard Lührmann, Markus Deckers, Indira Memet, Markus T. Bohnsack, Bernhard Schmidt, Peter Rehling, Kum-Loong Boon, Enrico Schleiff, Anne Clancy, Alexandra Z. Andreou
Publikováno v:
RNA Biology
A rapidly increasing number of RNA helicases are implicated in several distinct cellular processes, however, the modes of regulation of multifunctional RNA helicases and their recruitment to different target complexes have remained unknown. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd009763effb9619e704a15475f9a725
http://resolver.sub.uni-goettingen.de/purl?gs-1/13404
http://resolver.sub.uni-goettingen.de/purl?gs-1/13404
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 2, Pp 276-287 (2016)
In eukaryotes, oxidized PUFAs, so-called oxylipins, are vital signaling molecules. The first step in their biosynthesis may be catalyzed by a lipoxygenase (LOX), which forms hydroperoxides by introducing dioxygen into PUFAs. Here we characterized Csp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7560e0701ed3b5910407ef1a13d08d44
https://europepmc.org/articles/PMC4727423/
https://europepmc.org/articles/PMC4727423/