Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alexandra Yu. Skorokhodova"'
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 449 (2024)
Inverted fatty acid β-oxidation represents a versatile biochemical platform for biosynthesis by the engineered microbial strains of numerous value-added chemicals from convenient and abundant renewable carbon sources, including biomass-derived sugar
Externí odkaz:
https://doaj.org/article/123ec18a288f46e9b98d403cb31f067a
Publikováno v:
Biotechnology Reports, Vol 33, Iss , Pp e00703- (2022)
Escherichia coli was engineered for efficient aerobic conversion of glucose to fumaric acid. A novel design for biosynthesis of the target product through the modified TCA cycle rather than via glyoxylate shunt, implying oxaloacetate formation from p
Externí odkaz:
https://doaj.org/article/d49b835eff1b424e9e2187dda4aa8ce6
Autor:
Alexandra Yu. Skorokhodova, Anastasiya A. Stasenko, Natalya V. Krasilnikova, Andrey Yu. Gulevich, Vladimir G. Debabov
Publikováno v:
Fermentation, Vol 8, Iss 12, p 738 (2022)
Malic acid is a versatile building-block chemical that can serve as a precursor of numerous valuable products, including food additives, pharmaceuticals, and biodegradable plastics. Despite the present petrochemical synthesis, malic acid, being an in
Externí odkaz:
https://doaj.org/article/a06afcbcdbbe489986b12f88d80cce4e
Publikováno v:
Biotechnology reports (Amsterdam, Netherlands). 33
Publikováno v:
Journal of Biotechnology. 293:47-55
An Escherichia coli K-12 MG1655-derived strain was engineered for respiro-fermentative production of pyruvate from glucose under anoxic conditions, which is preferred for industrial-scale microbial synthesis of valuable chemicals. The pathways of ana
Publikováno v:
Journal of Biotechnology. 244:16-24
Enantiomers of 3-hydroxybutyric acid (3-HB) can be used as the chiral precursors for the production of various optically active fine chemicals, including drugs, perfumes, and pheromones. In this study, Escherichia coli was engineered to produce (S)-3
Autor:
A. A. Morzhakova, Rustem Saidovich Shakulov, Debabov Vladimir G, Andrey Yu. Gulevich, Alexandra Yu. Skorokhodova
Publikováno v:
Biotechnology Letters. 35:577-583
Two different approaches to activate the glyoxylate bypass in model Escherichia coli K-12 strains for succinate biosynthesis during dual-phase fermentation in minimal glucose media were examined. Inactivation of IclR and FadR, the transcriptional reg
Publikováno v:
Journal of biotechnology. 214
Efficient succinate production in Escherichia coli is attained during anaerobic glucose fermentation in biosynthetic processes combining the reductive branch of the TCA cycle and the glyoxylate bypass. Pyruvate dehydrogenase (PDH) or pyruvate formate
Autor:
Andrey Yu. Gulevich, Rustem Saidovich Shakulov, Debabov Vladimir G, A. V. Sukhozhenko, Alexandra Yu. Skorokhodova
Publikováno v:
Biotechnology letters. 34(3)
The basic reactions of the clostridial 1-butanol biosynthesis pathway can be regarded to be the inverted reactions of the fatty acid β-oxidation pathway. A pathway for the biosynthesis of fuels and chemicals was recently engineered by combining enzy
Autor:
Joanna I. Katashkina, Irina L. Tokmakova, Lubov I Golubeva, Irina G. Andreeva, Alexandra Yu Skorokhodova, Sergey V. Mashko, Tatiana M. Kuvaeva, Irina Vladimirovna Biryukova
Publikováno v:
BMC Biotechnology, Vol 7, Iss 1, p 80 (2007)
BMC Biotechnology
BMC Biotechnology
Background RSF1010 is a well-studied broad-host-range plasmid able to be mobilized to different bacteria and plants. RSF1010-derived plasmid vectors are widely used in both basic research and industrial applications. In the latter case, exploiting of