Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Alexandra V. Andreeva"'
Autor:
Alexandra V. Andreeva, Xiaoping Du, David J. Visintine, Jaehyung Cho, Richard D. Minshall, Farnaz R. Bakhshi, Luiza Rusu, Osamu Kusano-Arai, Kyungho Kim, Nobuchika Suzuki, Sandra L. Haberichter, Aleksandra Stojanovic-Terpo, Takao Hamakubo, Guoquan Liu, Olga Chernaya, Hiroko Iwanari, Stephen M. Vogel, Tohru Kozasa
Publikováno v:
Blood. 123:442-450
von Willebrand factor (vWF) secretion by endothelial cells (ECs) is essential for hemostasis and thrombosis; however, the molecular mechanisms are poorly understood. Interestingly, we observed increased bleeding in EC-Gα13(-/-);Gα12(-/-) mice that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51feff594cf765a571724d0b6429ee55
https://doi.org/10.1182/blood-2013-03-489351
https://doi.org/10.1182/blood-2013-03-489351
Publikováno v:
Cellular Signalling. 24:2259-2267
Rhodopsin kinase (GRK1) is a member of G protein-coupled receptor kinase family and a key enzyme in the quenching of photolysed rhodopsin activity and desensitisation of the rod photoreceptor neurons. Like some other rod proteins involved in phototra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee115b0adabaed9a3c2bd5fe836fafd
https://doi.org/10.1016/j.cellsig.2012.07.020
https://doi.org/10.1016/j.cellsig.2012.07.020
Publikováno v:
Functional & Integrative Genomics. 12:11-23
PPP protein phosphatases are an important enzyme family involved in a variety of aspects of cellular signalling and metabolism. PPPs are ubiquitous in eukaryotes, and are also present in many bacteria. Canonical eukaryotic PPP phosphotases are repres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff88023e718bd35ae2b4bd2c47264ac
https://doi.org/10.1007/s10142-011-0254-z
https://doi.org/10.1007/s10142-011-0254-z
Autor:
Radu Neamu, Sasha Pavlovic, Tatyana A. Voyno-Yasenetskaya, Stephen M. Vogel, Jasmina Profirovic, Alexandra V. Andreeva, Jingyan Han, Ulrich Walter
Publikováno v:
Journal of Cellular Physiology. 226:1255-1264
Vasodilator-stimulated phosphoprotein (VASP) is implicated in the protection of the endothelial barrier in vitro and in vivo. The function of VASP in thrombin signaling in the endothelial cells (ECs) is not known. For the first time we studied the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27cd5dce093c0b1d0d8003b74519f189
https://doi.org/10.1002/jcp.22453
https://doi.org/10.1002/jcp.22453
Publikováno v:
International Journal for Parasitology. 38:1279-1295
The aim of this review is to provide a synthesis of the published experimental data on protein tyrosine phosphatases from parasitic protozoa, in silico analysis based on the availability of completed genomes and to place available data for individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999d02fbae17cd1c2c474bbb683d5d45
https://doi.org/10.1016/j.ijpara.2008.04.003
https://doi.org/10.1016/j.ijpara.2008.04.003
Publikováno v:
The FASEB Journal. 22:2821-2831
Gα12 constitutes, along with Gα13, one of the four families of α subunits of heterotrimeric G proteins. We found that the N terminus of Gα12, but not those of other Gα subunits, contains a predicted mitochondrial targeting sequence. Using confoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e699de26b5ed603fa6c06f1d3fd4961b
https://doi.org/10.1096/fj.07-104224
https://doi.org/10.1096/fj.07-104224
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 293:L259-L271
Molecular mechanisms of surfactant delivery to the air/liquid interface in the lung, which is crucial to lower the surface tension, have been studied for more than two decades. Lung surfactant is synthesized in the alveolar type II cells. Its deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f114d6d940cc78763a3d90e30f6963fd
https://doi.org/10.1152/ajplung.00112.2007
https://doi.org/10.1152/ajplung.00112.2007
Publikováno v:
Journal of Biological Chemistry. 280:25388-25395
Recent evidence has implicated the protein phosphatase PP5 in a variety of signaling pathways. Whereas several proteins have been identified that interact with PP5 and regulate its activity, a possibility of its regulation by second messengers remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3a20390e064dbacf1f8eb0fa69d685
https://doi.org/10.1074/jbc.m413202200
https://doi.org/10.1074/jbc.m413202200
Publikováno v:
Plant Physiology and Biochemistry. 39:1027-1035
Considerable physiological and biochemical evidence suggests that plants, like animals, widely use intracellular signalling coupled to heterotrimeric G proteins. Yet, the molecular components of this machinery remained elusive until recently. We over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5752868ad3e9110f772ad067d26a4b20
https://doi.org/10.1016/s0981-9428(01)01328-6
https://doi.org/10.1016/s0981-9428(01)01328-6
Publikováno v:
Molecular Cell Biology Research Communications. 4:345-352
Recently we identified novel plant Ser/Thr phosphatases, termed PP7, which belong to the PPP family and have no known close homologs in other kingdoms. We now addressed the intracellular location of Arabidopsis thaliana PP7 using GFP fusions and conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a5fd7a56ff0646e0c1187282495589
https://doi.org/10.1006/mcbr.2001.0302
https://doi.org/10.1006/mcbr.2001.0302