Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Alexandra Tikhomirova"'
Autor:
Alexandra Tikhomirova, Emmylee R. McNabb, Luca Petterlin, Georgia L. Bellamy, Kyaw H. Lin, Christopher A. Santoso, Ella S. Daye, Fatimah M. Alhaddad, Kah Peng Lee, Anna Roujeinikova
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-20 (2024)
Abstract Campylobacter jejuni is a very common cause of gastroenteritis, and is frequently transmitted to humans through contaminated food products or water. Importantly, C. jejuni infections have a range of short- and long-term sequelae such as irri
Externí odkaz:
https://doaj.org/article/25ab43b35c454493a85517ac2e1abf2d
Autor:
Hannah N. Agnew, Erin B. Brazel, Alexandra Tikhomirova, Mark van der Linden, Kimberley T. McLean, James C. Paton, Claudia Trappetti
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Streptococcus pneumoniae is the leading cause of bacterial paediatric meningitis after the neonatal period worldwide, but the bacterial factors and pathophysiology that drive pneumococcal meningitis are not fully understood. In this work, we have ide
Externí odkaz:
https://doaj.org/article/4cc47e2da4fb452bbcb8af1819fdaad2
Autor:
Mohammad M. Rahman, Alexandra Tikhomirova, Joyanta K. Modak, Melanie L. Hutton, Claudiu T. Supuran, Anna Roujeinikova
Publikováno v:
Gut Pathogens, Vol 12, Iss 1, Pp 1-7 (2020)
Abstract With the rise of bacterial resistance to conventional antibiotics, re-purposing of Food and Drug Administration (FDA) approved drugs currently used to treat non-bacteria related diseases as new leads for antibacterial drug discovery has beco
Externí odkaz:
https://doaj.org/article/f7789a24a4624956acb4bbf49a1e26c0
Publikováno v:
PLoS ONE, Vol 17, Iss 7 (2022)
Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis are bacterial species which frequently co-colonise the nasopharynx, but can also transit to the middle ear to cause otitis media. Chronic otitis media is often associated with
Externí odkaz:
https://doaj.org/article/ed39a2af5b964581aa5cfc682c1b8910
Autor:
Joyanta K. Modak, Alexandra Tikhomirova, Rebecca J. Gorrell, Mohammad M. Rahman, Despina Kotsanas, Tony M. Korman, Jose Garcia-Bustos, Terry Kwok, Richard L. Ferrero, Claudiu T. Supuran, Anna Roujeinikova
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1660-1667 (2019)
Ethoxzolamide (EZA), acetazolamide, and methazolamide are clinically used sulphonamide drugs designed to treat non-bacteria-related illnesses (e.g. glaucoma), but they also show antimicrobial activity against the gastric pathogen Helicobacter pylori.
Externí odkaz:
https://doaj.org/article/eb44d51be2b54acb9cc99fb86c5f74d4
Autor:
Alexandra Tikhomirova, Erin B. Brazel, Kimberley T. McLean, Hannah N. Agnew, James C. Paton, Claudia Trappetti
Publikováno v:
Pathogens, Vol 11, Iss 2, p 216 (2022)
The LuxS protein, encoded by luxS, is required for the production of autoinducer 2 (AI-2) in Streptococcus pneumoniae. The AI-2 molecule serves as a quorum sensing signal, and thus regulates cellular processes such as carbohydrate utilisation and bio
Externí odkaz:
https://doaj.org/article/f4e41ea4414940ccb18aec82d37031f1
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 7, p 1018 (2016)
General control non-repressible 5 (GCN5)-related N-acetyltransferases (GNAT) catalyze the transfer of an acyl moiety from acyl coenzyme A (acyl-CoA) to a diverse group of substrates and are widely distributed in all domains of life. This review of th
Externí odkaz:
https://doaj.org/article/ef7fcf3fc5ff4f198a8476ce01dd7c6e
Autor:
Alexandra, Tikhomirova, Erin B, Brazel, Kimberley T, McLean, Hannah N, Agnew, James C, Paton, Claudia, Trappetti
Publikováno v:
Pathogens (Basel, Switzerland). 11(2)
The LuxS protein, encoded by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::427b1605294503fc5dbd4f006014f3e4
https://pubmed.ncbi.nlm.nih.gov/35215159
https://pubmed.ncbi.nlm.nih.gov/35215159
Autor:
Tran Thanh Tung, Stephen P. Kidd, Hadi Rastin, Arash Mazinani, Sarah Vreugde, James Lee, J. Nine, Reza Ghomashchi, Alexandra Tikhomirova, Dusan Losic
Publikováno v:
Journal of materials chemistry. B. 9(32)
Plasma electrolytic oxidation (PEO) is a well-established technique for the treatment of titanium-based materials. The formed titania-PEO surface can improve the osseointegration properties of titanium implants. Nevertheless, it can not address bacte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc55318c12e640f085877ae7a9441578
https://pubmed.ncbi.nlm.nih.gov/34323241
https://pubmed.ncbi.nlm.nih.gov/34323241
Autor:
Jose F. Garcia-Bustos, Rebecca J. Gorrell, Alexandra Tikhomirova, Terry Kwok, Despina Kotsanas, Anna Roujeinikova, Joyanta K. Modak, Richard L. Ferrero, Tony M. Korman, Mohammad M. Rahman, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1660-1667 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
Ethoxzolamide (EZA), acetazolamide, and methazolamide are clinically used sulphonamide drugs designed to treat non-bacteria-related illnesses (e.g. glaucoma), but they also show antimicrobial activity against the gastric pathogen Helicobacter pylori.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bc4fcf670ab2a5d192fe53c2a768a7
https://doi.org/10.1080/14756366.2019.1663416
https://doi.org/10.1080/14756366.2019.1663416