Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Alexandra Teleki"'
Autor:
Nele-Johanna Hempel, Padryk Merkl, Matthias Manne Knopp, Ragna Berthelsen, Alexandra Teleki, Anders Kragh Hansen, Georgios A. Sotiriou, Korbinian Löbmann
Publikováno v:
Molecules, Vol 26, Iss 13, p 4035 (2021)
Laser radiation has been shown to be a promising approach for in situ amorphization, i.e., drug amorphization inside the final dosage form. Upon exposure to laser radiation, elevated temperatures in the compacts are obtained. At temperatures above th
Externí odkaz:
https://doaj.org/article/521318070367416199aea4048ba9fa36
Autor:
Nele-Johanna Hempel, Padryk Merkl, Matthias Manne Knopp, Ragna Berthelsen, Alexandra Teleki, Georgios A. Sotiriou, Korbinian Löbmann
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 917 (2021)
In this study, laser-induced in situ amorphization (i.e., amorphization inside the final dosage form) of the model drug celecoxib (CCX) with six different polymers was investigated. The drug–polymer combinations were studied with regard to the infl
Externí odkaz:
https://doaj.org/article/44615c36a38d4452ac95afc63d8664d0
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 493 (2020)
The intrinsic dissolution rate (IDR) of active pharmaceutical ingredients (API) is a key property that aids in early drug development, especially selecting formulation strategies to improve dissolution and thereby drug absorption in the intestine. He
Externí odkaz:
https://doaj.org/article/f2860a4247de420888264313978915b0
Publikováno v:
KONA Powder and Particle Journal, Vol 30, Iss 0, Pp 144-163 (2013)
Micronutrients and nutraceuticals such as vitamins, carotenoids, polyunsaturated fatty acids and polyphenols are classes of food ingredients that are essential for human health and well-being. These compounds are rarely added purely to the targeted f
Externí odkaz:
https://doaj.org/article/a14aecb329e34eed870d53334d63af24
Autor:
Giovanni Marco Saladino, Ronak Kakadiya, Shaquib Rahman Ansari, Alexandra Teleki, Muhammet Sadaka Toprak
Publikováno v:
Nanoscale Advances. 5:1323-1330
Nowadays, superparamagnetic iron oxide nanoparticles (SPIONs) have a dominant role in many subfields of biomedicine. Owing to their peculiar properties, they can be employed for magnetic separation, drug delivery, diagnostics, and hyperthermia treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607076f80f49c466f3d512d032fd559a
https://doi.org/10.1039/d2na00887d
https://doi.org/10.1039/d2na00887d
Autor:
Ann-Christin, Jacobsen, Aleksei, Kabedev, Patrick D, Sinko, Johan E, Palm, Christel A S, Bergström, Alexandra, Teleki
Publikováno v:
Drug delivery and translational research.
Lipid-based formulations (LBFs) are used by the pharmaceutical industry in oral delivery systems for both poorly water-soluble drugs and biologics. Digestibility is key for the performance of LBFs and in vitro lipolysis is commonly used to compare th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d50b3f592308eec9105d1cfcb3d1017
https://pubmed.ncbi.nlm.nih.gov/36209313
https://pubmed.ncbi.nlm.nih.gov/36209313
Autor:
Per Artursson, Christel A. S. Bergström, Alexandra Teleki, David Ahl, Shno Asad, Christine Wegler, Mia Phillipson
Publikováno v:
Journal of Pharmaceutical Sciences. 110:239-250
Inflammatory bowel disease (IBD) is a chronic condition resulting in impaired intestinal homeostasis. Current practices for diagnosis of IBD are challenged by invasive, demanding procedures. We hypothesized that proteomics analysis could provide a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1063769fc514bec9fc75ad491541f58d
https://doi.org/10.1016/j.xphs.2020.11.001
https://doi.org/10.1016/j.xphs.2020.11.001
Autor:
Ann-Christin Jacobsen, Aleksei Kabedev, Patrick D. Sinko, Johan E. Palm, Christel A. S. Bergström, Alexandra Teleki
Publikováno v:
Drug Delivery and Translational Research
Lipid-based formulations (LBFs) are used by the pharmaceutical industry in oral delivery systems for both poorly water-soluble drugs and biologics. Digestibility is key for the performance of LBFs and in vitro lipolysis is commonly used to compare th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46241416dc016a93d44ccd3a7d29f8a
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-490612
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-490612
Autor:
Anders Kragh Hansen, Ragna Berthelsen, Matthias Manne Knopp, Nele Johanna Hempel, Georgios A. Sotiriou, Alexandra Teleki, Korbinian Löbmann, Padryk Merkl
Publikováno v:
Molecules
Volume 26
Issue 13
Hempel, N J, Merkl, P, Knopp, M M, Berthelsen, R, Teleki, A, Hansen, A K, Sotiriou, G A & Löbmann, K 2021, ' The effect of the molecular weight of polyvinylpyrrolidone and the model drug on laser-induced in situ amorphization ', Molecules, vol. 26, no. 13, 4035 . https://doi.org/10.3390/molecules26134035
Molecules, Vol 26, Iss 4035, p 4035 (2021)
Volume 26
Issue 13
Hempel, N J, Merkl, P, Knopp, M M, Berthelsen, R, Teleki, A, Hansen, A K, Sotiriou, G A & Löbmann, K 2021, ' The effect of the molecular weight of polyvinylpyrrolidone and the model drug on laser-induced in situ amorphization ', Molecules, vol. 26, no. 13, 4035 . https://doi.org/10.3390/molecules26134035
Molecules, Vol 26, Iss 4035, p 4035 (2021)
Laser radiation has been shown to be a promising approach for in situ amorphization, i.e., drug amorphization inside the final dosage form. Upon exposure to laser radiation, elevated temperatures in the compacts are obtained. At temperatures above th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ffe5a3c6661dba39b13e9fcb4f0a7f2
https://pubmed.ncbi.nlm.nih.gov/34279377
https://pubmed.ncbi.nlm.nih.gov/34279377
Autor:
Padryk Merkl, Georgios A. Sotiriou, Ragna Berthelsen, Korbinian Löbmann, Matthias Manne Knopp, Nele-Johanna Hempel, Alexandra Teleki
Publikováno v:
Pharmaceutics, Vol 13, Iss 917, p 917 (2021)
Pharmaceutics
Hempel, N-J, Merkl, P, Knopp, M M, Berthelsen, R, Teleki, A, Sotiriou, G A & Lobmann, K 2021, ' The Influence of Drug-Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles ', Pharmaceutics, vol. 13, no. 6, 917 . https://doi.org/10.3390/pharmaceutics13060917
Volume 13
Issue 6
Pharmaceutics
Hempel, N-J, Merkl, P, Knopp, M M, Berthelsen, R, Teleki, A, Sotiriou, G A & Lobmann, K 2021, ' The Influence of Drug-Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles ', Pharmaceutics, vol. 13, no. 6, 917 . https://doi.org/10.3390/pharmaceutics13060917
Volume 13
Issue 6
In this study, laser-induced in situ amorphization (i.e., amorphization inside the final dosage form) of the model drug celecoxib (CCX) with six different polymers was investigated. The drug–polymer combinations were studied with regard to the infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3166a469e366e194cb52f5da89eceb
https://www.mdpi.com/1999-4923/13/6/917
https://www.mdpi.com/1999-4923/13/6/917