Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Alexandra T. P. Carvalho"'
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 6769-6774 (2019)
Externí odkaz:
https://doaj.org/article/7307c34c5910461ba452050faf150fef
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Biodegradable polymers, obtained via chemical synthesis, are currently employed in a wide range of biomedical applications. However, enzymatic polymerization is an attractive alternative because it is more sustainable and safer. Many lipases can be e
Externí odkaz:
https://doaj.org/article/75689ad70c55404186dc88f80df9255e
Autor:
Helena Ramos, Juliana Calheiros, Joana Almeida, Valentina Barcherini, Sónia Santos, Alexandra T. P. Carvalho, Maria M.M. Santos, Lucília Saraiva
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 596 (2020)
The Warburg effect is an emerging hallmark of cancer, which has the tumor suppressor p53 as its major regulator. Herein, we unveiled that p53 activation by (S)-tryptophanol-derived oxazoloisoindolinone (SLMP53-1) mediated the reprograming of glucose
Externí odkaz:
https://doaj.org/article/81675d12a87346c2a4e5b6efb1cb5fe3
Autor:
Silvia Anselmi, Alexandra T. P. Carvalho, Angela Serrano-Sanchez, Jose L. Ortega-Roldan, Jill Caswell, Iman Omar, Gustavo Perez-Ortiz, Sarah M. Barry, Thomas S. Moody, Daniele Castagnolo
Publikováno v:
ACS Catalysis. 13:4742-4751
Publikováno v:
Journal of Medicinal Chemistry. 66:2761-2772
Autor:
Carlos B. P. Oliveira, Sérgio R. S. Veloso, Elisabete M. S. Castanheira, Pedro R. Figueiredo, Alexandra T. P. Carvalho, Loic Hilliou, Renato B. Pereira, David M. Pereira, José A. Martins, Paula M. T. Ferreira, Peter J. Jervis
Publikováno v:
Soft matter. 18(20)
Short peptides capped on the N-terminus with aromatic groups are often able to form supramolecular hydrogels—self-assembled networks of fibrils able to trap water molecules. Typically, these hydrogelators can form stiff gels at concentrations of 0.
Autor:
Isaura Simões, Sónia F. G. Santos, Pedro R. Figueiredo, Beatriz C. Almeida, Alexandra T. P. Carvalho
Publikováno v:
The Journal of Physical Chemistry B. 125:4368-4374
The development of plant-based synthetic rennets is of high commercial interest, due to the current great consumer demand for animal product alternatives. A previously developed recombinant form of the aspartic protease cardosin B with a three-glycin
Nucleic acid technologies with designed delivery systems have surged as one the most promising therapies of the future, due to their contribution in combating SARS-CoV-2 severe disease. Nevertheless, the emergence of new variants of concern still rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::496ff348f359aac36de0802d3895ddcf
https://doi.org/10.1101/2022.02.09.479755
https://doi.org/10.1101/2022.02.09.479755
Autor:
Alexandra T. P. Carvalho, Daniel F. A. R. Dourado, Armando J. D. Silvestre, Pedro R. Figueiredo, Andreia F. Sousa, Beatriz C. Almeida
Publikováno v:
ChemCatChem. 12:4845-4852
Autor:
Félix Carvalho, Daniela Ferreira Rodrigues, Maria de Lourdes Bastos, Ricardo Pires das Neves, Vera Marisa Costa, Alexandra T. P. Carvalho
Publikováno v:
Archives of Toxicology. 94:2061-2078
α-Amanitin plays a key role in Amanita phalloides intoxications. The liver is a major target of α-amanitin toxicity, and while RNA polymerase II (RNA Pol II) transcription inhibition is a well-acknowledged mechanism of α-amanitin toxicity, other p