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pro vyhledávání: '"Alexandra T, Barbour"'
Publikováno v:
Nature Structural & Molecular Biology. 29:730-733
Publikováno v:
Nucleic Acids Research.
G-quadruplexes (G4s) are a set of stable secondary structures that form within guanine-rich regions of single-stranded nucleic acids that pose challenges for DNA maintenance. The G-rich DNA sequence at telomeres has a propensity to form G4s of variou
Publikováno v:
Current Opinion in Structural Biology. 81:102611
Publikováno v:
Nature structuralmolecular biology. 29(8)
Autor:
Alexandra T. Barbour, Arthur J. Zaug, Ci Ji Lim, Thomas R. Cech, Allison E. McKay, Deborah S. Wuttke
The single-stranded DNA-binding CTC1-STN1-TEN1 (CST) complex is essential for telomere maintenance and genome-wide replication recovery, processes that are critical for genome stability. Here, we report the 2.95 Å cryo-EM structure of human CST boun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477478640d6ef96040d0314c69bf9ad2
Autor:
Thomas R. Cech, Deborah S. Wuttke, Karen J. Goodrich, Allison E. McKay, Ci Ji Lim, Arthur J. Zaug, Alexandra T. Barbour
Publikováno v:
Science
Architecture of DNA-organizing complex The highly conserved mammalian CTC1-STN1-TEN1 (CST) complex is critical for genome stability and telomere maintenance. Lim et al. solved the structure of the human CST complex using cryo–electron microscopy. C