Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexandra Stroh-Dege"'
Autor:
Jeannine Lacroix, Zoltán Kis, Rafael Josupeit, Franziska Schlund, Alexandra Stroh-Dege, Monika Frank-Stöhr, Barbara Leuchs, Jörg R. Schlehofer, Jean Rommelaere, Christiane Dinsart
Publikováno v:
Viruses, Vol 10, Iss 6, p 302 (2018)
About 70% of all Ewing sarcoma (EWS) patients are diagnosed under the age of 20 years. Over the last decades little progress has been made towards finding effective treatment approaches for primarily metastasized or refractory Ewing sarcoma in young
Externí odkaz:
https://doaj.org/article/2aae36d9e1f6498195aed00ddcd7999b
Autor:
Hamidreza Hashemi, Alexandra-Larisa Condurat, Alexandra Stroh-Dege, Nadine Weiss, Carsten Geiss, Jill Pilet, Carles Cornet Bartolomé, Jean Rommelaere, Nathalie Salomé, Christiane Dinsart
Publikováno v:
Viruses, Vol 10, Iss 4, p 150 (2018)
Single nucleotide changes were introduced into the non-structural (NS) coding sequence of the H-1 parvovirus (PV) infectious molecular clone and the corresponding virus stocks produced, thereby generating H1-PM-I, H1-PM-II, H1-PM-III, and H1-DM. The
Externí odkaz:
https://doaj.org/article/45cf628e0a5c491cbefb3353393e9228
Autor:
R Josupeit, Jörg R. Schlehofer, Jeannine Lacroix, Zoltán Kis, Barbara Leuchs, Alexandra Stroh-Dege, Monika Frank-Stöhr, Jean Rommelaere, Franziska Schlund, Christiane Dinsart
Publikováno v:
Viruses
Volume 10
Issue 6
Viruses, Vol 10, Iss 6, p 302 (2018)
Volume 10
Issue 6
Viruses, Vol 10, Iss 6, p 302 (2018)
About 70% of all Ewing sarcoma (EWS) patients are diagnosed under the age of 20 years. Over the last decades little progress has been made towards finding effective treatment approaches for primarily metastasized or refractory Ewing sarcoma in young
Autor:
Nadine Weiss, Jean Rommelaere, Nathalie Salomé, Alexandra Stroh-Dege, Christiane Dinsart, Hamidreza Hashemi, Jill Pilet, Alexandra Larisa Condurat, Carles Cornet Bartolomé, Carsten Geiss
Publikováno v:
Viruses; Volume 10; Issue 4; Pages: 150
Viruses, Vol 10, Iss 4, p 150 (2018)
Viruses
Viruses, Vol 10, Iss 4, p 150 (2018)
Viruses
Single nucleotide changes were introduced into the non-structural (NS) coding sequence of the H-1 parvovirus (PV) infectious molecular clone and the corresponding virus stocks produced, thereby generating H1-PM-I, H1-PM-II, H1-PM-III, and H1-DM. The
Autor:
Isabelle Ronsse, Katrien Van Raemdonck, Christiane Dinsart, Alexandra Stroh-Dege, Muriel Lavie, Sofie Struyf, Jo Van Damme, Jean Rommelaere, Kalliopi Pervolaraki
Publikováno v:
Human gene therapy. 28(3)
Application of oncolytic viruses is a valuable option to broaden the armament of anticancer therapies, as these combine specific cytotoxic effects and immune-stimulating properties. The self-replicating H-1 parvovirus (H-1PV) is a prototypical oncoly
Autor:
Jean Rommelaere, Alexandra Stroh-Dege, Christiane Dinsart, Jozef Van Damme, Muriel Lavie, Sofie Struyf
Publikováno v:
Virology. 447(1-2):221-232
Anti-angiogenic therapy has been recognized as a powerful potential strategy for impeding the growth of various tumors. However no major therapeutic effects have been observed to date, mainly because of the emergence of several resistance mechanisms.
Publikováno v:
Journal of Virology. 86:7554-7564
An in-frame, 114-nucleotide-long deletion that affects the NS-coding sequence was created in the infectious molecular clone of the standard parvovirus H-1PV, thereby generating Del H-1PV. The plasmid was transfected and further propagated in permissi
Autor:
Stephanie Boelz, Christiane Dinsart, Alexandra Stroh-Dege, Jean Rommelaere, Susanne I. Lang, Jan J. Cornelis
Publikováno v:
Journal of Virology. 79:289-298
Gene therapy vectors have been developed from autonomous rodent parvoviruses that carry a therapeutic gene or a marker gene in place of the genes encoding the capsid proteins. These vectors are currently evaluated in preclinical experiments. The infe
Autor:
Ginette Balboni, Susanne I. Lang, Jean Rommelaere, Alexandra Stroh-Dege, Jan Cornelis, Christiane Dinsart
Publikováno v:
Current Gene Therapy. 4:249-261
Parvoviruses are small nuclear replicating DNA viruses. The rodent parvoviruses are usually weakly pathogenic in adult animals, bind to cell surface receptors which are fairly ubiquitously expressed on cells, and do not appear to integrate into host
SMAD4: a predictive marker of PDAC cell permissiveness for oncolytic infection with parvovirus H-1PV
Autor:
Jean Rommelaere, Alexandra Stroh-Dege, Christiane Dinsart, Sebastian Dempe, Elisabeth Schwarz
Publikováno v:
International journal of cancer. 126(12)
Pancreatic ductal adenocarcinoma (PDAC) represents the eighth frequent solid tumor and fourth leading cause of cancer death. Because current treatments against PDAC are still unsatisfactory, new anticancer strategies are required, including oncolytic