Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alexandra Sittka"'
Autor:
Christina E. Herkt, Brian E. Caffrey, Kristin Surmann, Sascha Blankenburg, Manuela Gesell Salazar, Anna L. Jung, Stefanie M. Herbel, Kerstin Hoffmann, Leon N. Schulte, Wei Chen, Alexandra Sittka-Stark, Uwe Völker, Martin Vingron, Annalisa Marsico, Wilhelm Bertrams, Bernd Schmeck
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Legionella pneumophila is an important cause of pneumonia. It invades alveolar macrophages and manipulates the immune response by interfering with signaling pathways and gene transcription to support its own replication. MicroRNAs (miRNAs) a
Externí odkaz:
https://doaj.org/article/f562f453df8b4591a2a3cac252c1f3ca
Autor:
Anna Lena Jung, Christina Elena Herkt, Christine Schulz, Kathrin Bolte, Kerstin Seidel, Nicoletta Scheller, Alexandra Sittka-Stark, Wilhelm Bertrams, Bernd Schmeck
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Extracellular vesicles from eukaryotic cells and outer membrane vesicles (OMVs) released from gram-negative bacteria have been described as mediators of pathogen-host interaction and intercellular communication. Legionella pneumophila (L. pn
Externí odkaz:
https://doaj.org/article/634e435cb02945d984a05ad1940c1919
Autor:
Lena Smirnova, Katharina Block, Alexandra Sittka, Michael Oelgeschläger, Andrea E M Seiler, Andreas Luch
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98892 (2014)
Studying chemical disturbances during neural differentiation of murine embryonic stem cells (mESCs) has been established as an alternative in vitro testing approach for the identification of developmental neurotoxicants. miRNAs represent a class of s
Externí odkaz:
https://doaj.org/article/775750d3786c47be961953a0ae2283f8
Autor:
Alexandra Sittka, Sacha Lucchini, Kai Papenfort, Cynthia M Sharma, Katarzyna Rolle, Tim T Binnewies, Jay C D Hinton, Jörg Vogel
Publikováno v:
PLoS Genetics, Vol 4, Iss 8, p e1000163 (2008)
Recent advances in high-throughput pyrosequencing (HTPS) technology now allow a thorough analysis of RNA bound to cellular proteins, and, therefore, of post-transcriptional regulons. We used HTPS to discover the Salmonella RNAs that are targeted by t
Externí odkaz:
https://doaj.org/article/7276c466503346a29788af0753bc0d8d
Autor:
Kathrin Griss, Claus Vogelmeier, Alexandra Sittka-Stark, M Han, Norbert Suttorp, Bernd Schmeck, Kerstin Seidel, Florian Finkernagel, Stefan Hippenstiel, Julio Vera, Wilhelm Bertrams, Jochen Wilhelm, Andreas Klemmer, Timm Greulich
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Lower respiratory infections, such as community-acquired pneumonia (CAP), and chronic obstructive pulmonary disease (COPD) rank among the most frequent causes of death worldwide. Improved diagnostics and profound pathophysiological insights are urgen
Autor:
Brian E. Caffrey, C Herkt, Leon N. Schulte, Annalisa Marsico, Bernd Schmeck, Kerstin Hoffmann, Wei Chen, Uwe Völker, Wilhelm Bertrams, Stefanie M. Herbel, Sascha Blankenburg, Alexandra Sittka-Stark, Manuela Gesell Salazar, Kristin Surmann, Anna L. Jung, Martin Vingron
Publikováno v:
mBio 11:e03155-19 (2020)
mBio, Vol 11, Iss 2 (2020)
mBio
mBio, Vol 11, Iss 2, p e03155-19 (2020)
mBio, Vol 11, Iss 2 (2020)
mBio
mBio, Vol 11, Iss 2, p e03155-19 (2020)
Cases of Legionella pneumophila pneumonia occur worldwide, with potentially fatal outcome. When causing human disease, Legionella injects a plethora of virulence factors to reprogram macrophages to circumvent immune defense and create a replication n
Autor:
Bernd Schmeck, Kathrin Griss, Andreas Klemmer, J Vera-Gonzalez, Claus Vogelmeier, Norbert Suttorp, Kerstin Seidel, Florian Finkernagel, Stefan Hippenstiel, Alexandra Sittka-Stark, M Han, Martin Eberhardt, Timm Greulich, Wilhelm Bertrams, Jochen Wilhelm
Publikováno v:
61. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e.V..
Autor:
Kerstin Seidel, Kathrin Griss, Claus Vogelmeier, J Vera-Gonzalez, Florian Finkernagel, Bernd Schmeck, Alexandra Sittka-Stark, M Han, Norbert Suttorp, Stefan Hippenstiel, Andreas Klemmer, Timm Greulich, Wilhelm Bertrams, Jochen Wilhelm
Publikováno v:
61. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e.V..
Autor:
Annalisa Marsico, Bernd Schmeck, Wilhelm Bertrams, I DuBois, Martin Vingron, Brian E. Caffrey, Alexandra Sittka-Stark, Martin Eberhardt, M Schweiger, Julio Vera
Publikováno v:
The Journal of Infectious Diseases
Background: Legionella pneumophila ( L. pneumophila ) is a causative agent of severe pneumonia. Infection leads to a broad host cell response, as evident e.g. on the transcriptional level. Chromatin modifications, which control gene expression, play
Autor:
Wilhelm Bertrams, Kerstin Seidel, Kathrin Griss, Andreas Klemmer, Alexandra Sittka-Stark, M Han, Stefan Hippenstiel, Christoph Nell, Bernd Schmeck, B Klapdor
Publikováno v:
Pneumologie. 70