Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alexandra Sisakova"'
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-17 (2017)
Abstract Background Proper DNA replication is essential for faithful transmission of the genome. However, replication stress has serious impact on the integrity of the cell, leading to stalling or collapse of replication forks, and has been determine
Externí odkaz:
https://doaj.org/article/121410ae72b546699f2b61ab772eec5f
Autor:
Rebecca C Burgess, Marek Sebesta, Alexandra Sisakova, Victoria P Marini, Michael Lisby, Jiri Damborsky, Hannah Klein, Rodney Rothstein, Lumir Krejci
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82630 (2013)
Rad54 is an ATP-driven translocase involved in the genome maintenance pathway of homologous recombination (HR). Although its activity has been implicated in several steps of HR, its exact role(s) at each step are still not fully understood. We have i
Externí odkaz:
https://doaj.org/article/64188a082a04436cb02cf3915790e109
Autor:
Vitali Bialevich, Rüdiger Ettrich, David Reha, Jannette Carey, Marie Weiserova, Lumir Krejci, Dhiraj Sinha, Alena Guzanova, Katsiaryna Shamayeva, Alexandra Sisakova, Eva Csefalvay
Publikováno v:
Journal of molecular modeling. 24(7)
Type I restriction-modification enzymes differ significantly from the type II enzymes commonly used as molecular biology reagents. On hemi-methylated DNAs type I enzymes like the EcoR124I restriction-modification complex act as conventional adenine m
Autor:
Dana Branzei, Demis Menolfi, Lumir Krejci, Madhusoodanan Urulangodi, Barnabas Szakal, Alexandra Sisakova, Julie Sollier, Marek Sebesta
Publikováno v:
Genes & Development. 29:2067-2080
Accurate completion of replication relies on the ability of cells to activate error-free recombination-mediated DNA damage bypass at sites of perturbed replication. However, as anti-recombinase activities are also recruited to replication forks, how
Autor:
Steven J. Brill, Lumir Krejci, Melita Chavdarova, Victoria Marini, Michael Lisby, Alexandra Sisakova, Dana Vigasova, Hana Sedlackova
Publikováno v:
Nucleic Acids Research
Chavdarova, M, Marini, V, Sisakova, A, Sedlackova, H, Vigasova, D, Brill, S J, Lisby, M & Krejci, L 2015, ' Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates ', Nucleic Acids Research, vol. 43, no. 7, pp. 3626-3642 . https://doi.org/10.1093/nar/gkv198
Chavdarova, M, Marini, V, Sisakova, A, Sedlackova, H, Vigasova, D, Brill, S J, Lisby, M & Krejci, L 2015, ' Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates ', Nucleic Acids Research, vol. 43, no. 7, pp. 3626-3642 . https://doi.org/10.1093/nar/gkv198
A variety of DNA lesions, secondary DNA structures or topological stress within the DNA template may lead to stalling of the replication fork. Recovery of such forks is essential for the maintenance of genomic stability. The structure-specific endonu
Publikováno v:
BMC Biology
BMC Biology, Vol 15, Iss 1, Pp 1-17 (2017)
BMC Biology, Vol 15, Iss 1, Pp 1-17 (2017)
Background Proper DNA replication is essential for faithful transmission of the genome. However, replication stress has serious impact on the integrity of the cell, leading to stalling or collapse of replication forks, and has been determined as a dr
Autor:
Marek Sebesta, Lajos Pintér, Alexandra Sisakova, Lajos Haracska, Peter Kolesar, Serge Gangloff, Valeria Szukacsov, Nicolas Plault, Lumir Krejci, Thomas Robert, Victoria Marini, Peter Burkovics
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2013, 32 (5), pp.742-755. ⟨10.1038/emboj.2013.9⟩
The EMBO Journal
EMBO Journal, 2013, 32 (5), pp.742-755. ⟨10.1038/emboj.2013.9⟩
EMBO Journal, EMBO Press, 2013, 32 (5), pp.742-755. ⟨10.1038/emboj.2013.9⟩
The EMBO Journal
EMBO Journal, 2013, 32 (5), pp.742-755. ⟨10.1038/emboj.2013.9⟩
Completion of DNA replication needs to be ensured even when challenged with fork progression problems or DNA damage. PCNA and its modifications constitute a molecular switch to control distinct repair pathways. In yeast, SUMOylated PCNA (S-PCNA) recr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c79efa0451792bd35f747f646ad42a
https://hal.archives-ouvertes.fr/hal-03454103
https://hal.archives-ouvertes.fr/hal-03454103
Autor:
Michael Lisby, Rebecca C. Burgess, Lumir Krejci, Marek Sebesta, Jiri Damborsky, Alexandra Sisakova, Victoria Marini, Hannah L. Klein, Rodney Rothstein
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82630 (2013)
PLoS ONE
Burgess, R C, Sebesta, M, Sisakova, A, Marini, V P, Lisby, M, Damborsky, J, Klein, H, Rothstein, R & Krejci, L 2013, ' The PCNA interaction protein box sequence in Rad54 is an integral part of its ATPase domain and is required for efficient DNA repair and recombination ', PLoS ONE, vol. 8, no. 12, pp. e82630 . https://doi.org/10.1371/journal.pone.0082630
PLoS ONE
Burgess, R C, Sebesta, M, Sisakova, A, Marini, V P, Lisby, M, Damborsky, J, Klein, H, Rothstein, R & Krejci, L 2013, ' The PCNA interaction protein box sequence in Rad54 is an integral part of its ATPase domain and is required for efficient DNA repair and recombination ', PLoS ONE, vol. 8, no. 12, pp. e82630 . https://doi.org/10.1371/journal.pone.0082630
Rad54 is an ATP-driven translocase involved in the genome maintenance pathway of homologous recombination (HR). Although its activity has been implicated in several steps of HR, its exact role(s) at each step are still not fully understood. We have i