Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Alexandra Serre"'
Autor:
Eric Marsault, Robin Van Den Hauwe, Claude Spino, Sabrina Saibi, Xavier Sainsily, Jérôme Côté, Louise Simard, Alexandra Serre, Michel Bouvier, Steven Ballet, Mannix Auger-Messier, Jean-Michel Longpré, Lounès Haroune, Pierre Couvineau, Olivier Lesur, Alexandre Murza, Marco Echevarria, Kien Trân, Léa Théroux, Philippe Sarret
Publikováno v:
Journal of Medicinal Chemistry. 64:5345-5364
Side-chain-constrained amino acids are useful tools to modulate the biological properties of peptides. In this study, we applied side-chain constraints to apelin-13 (Ape13) by substituting the Pro12 and Phe13 positions, affecting the binding affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6326583d9752754accc55d2ff5cb76
https://doi.org/10.1021/acs.jmedchem.0c01941
https://doi.org/10.1021/acs.jmedchem.0c01941
Autor:
Athina Polykandritou, Alexandra Serre, Hannah Spencer, Goreti R. Morais, Amanda Race, Steven Shnyder, Paul Loadman, Robert A. Falconer
Publikováno v:
Cancer Research. 82:1074-1074
ICT3205 is a targeted cytotoxic agent, comprised of an MT1-MMP-specific peptide and a paclitaxel warhead. Paclitaxel, originally approved in 1992, is one of the most commonly used chemotherapies for various cancer types, but is often characterized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48e0fa8668e9570b1368b8c045e37395
https://doi.org/10.1158/1538-7445.am2022-1074
https://doi.org/10.1158/1538-7445.am2022-1074