Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Alexandra Schurer"'
Autor:
Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Eren L. Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace Y. Q. Han, Aspen J. Pierson, Michael Xiao, Xuejing Yang, Lindsey M. Kuehm, Yuning Hong, Diu T. T. Nguyen, Gabriela Chiosis, Alex Kentsis, Christina Leslie, Ly P. Vu, Michael G. Kharas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Tissue homeostasis is maintained after stress by engaging and activating the hematopoietic stem and progenitor compartments in the blood. Hematopoietic stem cells (HSCs) are essential for long-term repopulation after secondary transplantatio
Externí odkaz:
https://doaj.org/article/a849e3d3deda463181789ab17c11b2cd
Autor:
Diu T. T. Nguyen, Yuheng Lu, Eren L. Chu, Xuejing Yang, Sun-Mi Park, Zi-Ning Choo, Christopher R. Chin, Camila Prieto, Alexandra Schurer, Ersilia Barin, Angela M. Savino, Saroj Gourkanti, Payal Patel, Ly P. Vu, Christina S. Leslie, Michael G. Kharas
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract The cell-context dependency for RNA binding proteins (RBPs) mediated control of stem cell fate remains to be defined. Here we adapt the HyperTRIBE method using an RBP fused to a Drosophila RNA editing enzyme (ADAR) to globally map the mRNA t
Externí odkaz:
https://doaj.org/article/57d9dd401d274463904c8c3f4b95b1ec
Autor:
Gerard Minuesa, Steven K. Albanese, Wei Xie, Yaniv Kazansky, Daniel Worroll, Arthur Chow, Alexandra Schurer, Sun-Mi Park, Christina Z. Rotsides, James Taggart, Andrea Rizzi, Levi N. Naden, Timothy Chou, Saroj Gourkanti, Daniel Cappel, Maria C. Passarelli, Lauren Fairchild, Carolina Adura, J. Fraser Glickman, Jessica Schulman, Christopher Famulare, Minal Patel, Joseph K. Eibl, Gregory M. Ross, Shibani Bhattacharya, Derek S. Tan, Christina S. Leslie, Thijs Beuming, Dinshaw J. Patel, Yehuda Goldgur, John D. Chodera, Michael G. Kharas
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The RNA binding protein MUSASHI-2 (MSI2) is a potential therapeutic target for acute myeloid leukemia. Here the authors identify a small molecule inhibitor of MSI2 and characterize its effects in a murine leukemia model.
Externí odkaz:
https://doaj.org/article/0841d30974ee49439a137cb5c41e499b
Autor:
Yuanming Cheng, Hanzhi Luo, Franco Izzo, Brian F. Pickering, Diu Nguyen, Robert Myers, Alexandra Schurer, Saroj Gourkanti, Jens C. Brüning, Ly P. Vu, Samie R. Jaffrey, Dan A. Landau, Michael G. Kharas
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1703-1716.e6 (2019)
Summary: Stem cells balance cellular fates through asymmetric and symmetric divisions in order to self-renew or to generate downstream progenitors. Symmetric commitment divisions in stem cells are required for rapid regeneration during tissue damage
Externí odkaz:
https://doaj.org/article/d0575c334f4841de919b97361dfd2bba
Autor:
Lindsay M. Gurska, Rachel Okabe, Alexandra Schurer, Meng Maxine Tong, Mark Soto, Daniel Choi, Kristina Ames, Shira Glushakow-Smith, Allison Montoya, Ellen Tein, Linde A. Miles, Haiying Cheng, Pamela Hankey-Giblin, Ross L. Levine, Swati Goel, Balazs Halmos, Kira Gritsman
Publikováno v:
Clinical Cancer Research. 29:943-956
Purpose:The Philadelphia chromosome–negative myeloproliferative neoplasms (MPN) polycythemia vera, essential thrombocythemia, and primary myelofibrosis are characterized by JAK/STAT pathway activation. JAK inhibitors are approved for MPN treatment,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bec2da24f5123fa74a19314f994f52
https://doi.org/10.1158/1078-0432.ccr-22-1763
https://doi.org/10.1158/1078-0432.ccr-22-1763
Autor:
Sara Viragova, Luis Aparicio, Pierangela Palmerini, Junfei Zhao, Luis E Valencia Salazar, Alexandra Schurer, Anika Dhuri, Debashis Sahoo, Christopher A Moskaluk, Raul Rabadan, Piero Dalerba
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Background Adenoid Cystic Carcinoma (ACC) is a lethal malignancy of exocrine glands, characterized by the co-existence within tumor tissues of two distinct populations of cancer cells, phenotypically similar to the myoepithelial and ductal lineages o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a537affb8411807a6c66393bae7677a
https://doi.org/10.1093/jnci/djad062
https://doi.org/10.1093/jnci/djad062
Autor:
Kira Gritsman, Balazs Halmos, Swati Goel, Ross L. Levine, Pamela Hankey-Giblin, Haiying Cheng, Linde A. Miles, Ellen Tein, Allison Montoya, Shira Glushakow-Smith, Kristina Ames, Daniel Choi, Mark Soto, Meng Maxine Tong, Alexandra Schurer, Rachel Okabe, Lindsay M. Gurska
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a2db7517532a21283e744b7dc30777
https://doi.org/10.1158/1078-0432.22490719
https://doi.org/10.1158/1078-0432.22490719
Autor:
Kira Gritsman, Balazs Halmos, Swati Goel, Ross L. Levine, Pamela Hankey-Giblin, Haiying Cheng, Linde A. Miles, Ellen Tein, Allison Montoya, Shira Glushakow-Smith, Kristina Ames, Daniel Choi, Mark Soto, Meng Maxine Tong, Alexandra Schurer, Rachel Okabe, Lindsay M. Gurska
Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f70bff6ddb24228f80d3a3280f122f
https://doi.org/10.1158/1078-0432.22490728.v1
https://doi.org/10.1158/1078-0432.22490728.v1
Autor:
Kira Gritsman, Balazs Halmos, Swati Goel, Ross L. Levine, Pamela Hankey-Giblin, Haiying Cheng, Linde A. Miles, Ellen Tein, Allison Montoya, Shira Glushakow-Smith, Kristina Ames, Daniel Choi, Mark Soto, Meng Maxine Tong, Alexandra Schurer, Rachel Okabe, Lindsay M. Gurska
Table S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7060c8115921bea484773256515058a8
https://doi.org/10.1158/1078-0432.22490725.v1
https://doi.org/10.1158/1078-0432.22490725.v1
Autor:
Kira Gritsman, Balazs Halmos, Swati Goel, Ross L. Levine, Pamela Hankey-Giblin, Haiying Cheng, Linde A. Miles, Ellen Tein, Allison Montoya, Shira Glushakow-Smith, Kristina Ames, Daniel Choi, Mark Soto, Meng Maxine Tong, Alexandra Schurer, Rachel Okabe, Lindsay M. Gurska
Purpose:The Philadelphia chromosome–negative myeloproliferative neoplasms (MPN) polycythemia vera, essential thrombocythemia, and primary myelofibrosis are characterized by JAK/STAT pathway activation. JAK inhibitors are approved for MPN treatment,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7256915ea837f90bfe5b9668298d86
https://doi.org/10.1158/1078-0432.c.6533203.v1
https://doi.org/10.1158/1078-0432.c.6533203.v1