Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alexandra Schmid-Kotsas"'
Autor:
Max G. Bachem, Changxian Shen, Alexandra Schmid-Kotsas, Hans-Juergen Gross, Andreas Buck, Christiane Matuschek, Sven N. Reske, Bülent Polat
Publikováno v:
Cancer Gene Therapy. 10:403-410
Survivin is expressed in most cancers but is undetectable in differentiated adult cells, and plays an important role both in the suppression of apoptosis and mitotic spindle checkpoint; thus it has attracted great interest as a potential drug target.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8bc7db53dd256e600301c248edc85f
https://doi.org/10.1038/sj.cgt.7700581
https://doi.org/10.1038/sj.cgt.7700581
Autor:
Adolf Gruenert, Max G. Bachem, Alexandra Schmid-Kotsas, Peter M. Jehle, Cornelia Haug, Theresia Linder, Eva Rozdzinski
Publikováno v:
Clinical Science. 103:76S-80S
Several studies have demonstrated that endothelin-1 (ET-1) plays an important pathophysiological role in ischaemic renal failure and drug-induced renal injury, such as cyclosporine A (CsA)- and tacrolimus-associated nephrotoxicity. This study aimed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a77467ca6ae6e3602a8f7bc5fd60f1
https://doi.org/10.1042/cs103s076s
https://doi.org/10.1042/cs103s076s
Autor:
Changxian Shen, Nicole Klug, Gerhard Mehrke, Max G. Bachem, Hans-Jürgen Gross, Holger Schirrmeister, Alexandra Schmid-Kotsas, Sven N. Reske, Albrecht Guhlmann, Gerd Munzert, Andreas Buck
Publikováno v:
Scopus-Elsevier
The aim of this study was to enhance the delivery and thus anti-tumoral efficiency of antisense bcl-2 oligonucleotides (ODN's).Bcl-2 overexpressing DoHH2 lymphoma and HeLa-cells were transfected with ODN's using a polycationic liposome preparation. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2195c917068fb708e2fb3829b21017a0
https://doi.org/10.1089/10849780260179242
https://doi.org/10.1089/10849780260179242
Autor:
Jinshun Zhao, Andre Menke, Hans Weidenbach, Guido Adler, Wilhelm Schneiderhan, Andreas K. Nussler, Adolf Grünert, Roland M. Schmid, Max G. Bachem, Alexandra Schmid-Kotsas
Publikováno v:
Hepatology. 34:729-737
Cumulating evidence suggests that oxidative stress resulting in lipid peroxidation and protein modification is involved in the pathogenesis of chronic liver injury and fibrogenesis. We investigated the effects of oxidized low-density lipoproteins (ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f925e84d366bc157092dd94a979c15
https://doi.org/10.1053/jhep.2001.27828
https://doi.org/10.1053/jhep.2001.27828
Autor:
Hans-Juergen Gross, Ulrike Zorn, Alexandra Schmid-Kotsas, Sabine Schuett, Max G. Bachem, Adolf Gruenert, Cornelia Haug
Publikováno v:
Journal of Molecular and Cellular Cardiology. 33:1701-1712
Endothelin-1 (ET-1) is a potent vasoconstrictive peptide exerting its effects predominantly by paracrine and autocrine mechanisms. ET-1 acts as a mitogen and co-mitogen on vascular smooth muscle cells, and accumulating evidence suggests that ET-1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73cc45d444c7bb76c4aeb3eb29bfcd2
https://doi.org/10.1006/jmcc.2001.1421
https://doi.org/10.1006/jmcc.2001.1421
Autor:
Alexandra Schmid-Kotsas, Peter Schaarschmidt, Paul Walther, Bianca Vaida, Robert Pretsch, Michael Winkler, Detlef Michel, Max G. Bachem, Barbara Reinhardt, Thomas Mertens, Shaoxia Zhou
Publikováno v:
The Journal of general virology. 87(Pt 10)
Human cytomegalovirus (HCMV) infection appears to be linked to the pathogenesis of atherosclerosis. An association between HCMV infection and an enhanced restenosis rate as well as the induction of vasculopathies after solid organ transplantation has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c011ad365ae76e3a5f86a7721813fc81
https://pubmed.ncbi.nlm.nih.gov/16963742
https://pubmed.ncbi.nlm.nih.gov/16963742
Autor:
Andreas Buck, Hans G. Beger, Marco Ramadani, Alexandra Schmid-Kotsas, Shaoxia Zhou, Marco Siech, Guido Adler, Max G. Bachem, Marion Schünemann
Publikováno v:
Gastroenterology. 128(4)
Background & Aims: Tumor desmoplasia is one of the representative histopathologic findings in ductal pancreatic adenocarcinoma. The aims of this study were to examine the cellular and molecular mechanisms of fibrogenesis associated with pancreatic ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d5df1fe8d01072ab90ae4ed7664196
https://pubmed.ncbi.nlm.nih.gov/15825074
https://pubmed.ncbi.nlm.nih.gov/15825074
Autor:
Hans G. Beger, Marco Siech, Thomas Mathias Gress, Alexandra Schmid-Kotsas, Guido Adler, Max G. Bachem
Publikováno v:
Pancreatic Disease ISBN: 9781447134916
Pancreas fibrosis is a result of an increased deposition and a reduced degradation of extracellular matrix.1,2 Until recently the molecular mechanisms and cell-cell interactions resulting in pancreas fibrosis were largely unknown. Years ago the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99985c1893769a2395723bd7388dd325
https://doi.org/10.1007/978-1-85233-904-3_18
https://doi.org/10.1007/978-1-85233-904-3_18
Publikováno v:
Chinese medical journal. 116(12)
To study the sensitivity and specificity of different staining methods to monitor apoptosis induced by oxidative stress in adherent cells.Sensitivity and specificity of several common methods for apoptosis determination were evaluated (Apo2.7-express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc95268064a2108a8a50ba7c505460e8
https://pubmed.ncbi.nlm.nih.gov/14687485
https://pubmed.ncbi.nlm.nih.gov/14687485
Autor:
Eva Rozdzinski, Theresia Linder, Alexandra Schmid-Kotsas, Max G. Bachem, Adolf Gruenert, Cornelia Haug
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 16(12)
Background. Endothelin-1 (ET-1) is a potent vasoconstrictive peptide which plays an important pathophysiological role in ischaemic renal failure and drug-induced renal injury such as cyclosporin A (CsA)- and tacrolimus-associated nephrotoxicity. In c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc4cc9878f2b257cd6418e2145a0349
https://pubmed.ncbi.nlm.nih.gov/11733621
https://pubmed.ncbi.nlm.nih.gov/11733621