Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alexandra Schele"'
Autor:
Karl-Peter Hopfner, Alexandra Schele, Ursula J.E. Seidel, Nadja C. Fenn, Annemarie Honegger, Christian B. Schiller, Todd A. Braciak, Sarah Wildenhain, Fuat Oduncu, Ingo Schubert, Kerstin Lämmermann, Peter Lang, Georg H. Fey, Claudia C. Roskopf, Uwe Jacob
Publikováno v:
Oncotarget
// Christian B. Schiller 1, * , Todd A. Braciak 2, * , Nadja C. Fenn 1, * , Ursula J. E. Seidel 3, * , Claudia C. Roskopf 2, * , Sarah Wildenhain 1, * , Annemarie Honegger * , Ingo A. Schubert 5 , Alexandra Schele 1 , Kerstin Lammermann 2 , Georg H.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9594975ab5fee990d155d3a61be0db
https://pubmed.ncbi.nlm.nih.gov/27825135
https://pubmed.ncbi.nlm.nih.gov/27825135
Publikováno v:
Journal of Biological Chemistry. 283:7962-7971
The ATP binding cassette enzyme ABCE1 (also known as RNase-L (ribonuclease L) inhibitor, Pixie, and HP68), one of the evolutionary most sequence-conserved enzymes, functions in translation initiation, ribosome biogenesis, and human immunodeficiency v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44184f6f97bd99ee540cd10df9b4c475
https://doi.org/10.1074/jbc.m707347200
https://doi.org/10.1074/jbc.m707347200
Publikováno v:
Nucleic Acids Research
DNA double-strand breaks (DSBs) threaten genome stability in all kingdoms of life and are linked to cancerogenic chromosome aberrations in humans. The Mre11:Rad50 (MR) complex is an evolutionarily conserved complex of two Rad50 ATPases and a dimer of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388e56788307b3c2fc7191d617eb94dc
https://pubmed.ncbi.nlm.nih.gov/21937514
https://pubmed.ncbi.nlm.nih.gov/21937514
Publikováno v:
Current biology : CB. 14(19)
Structural maintenance of chromosome (SMC) proteins play a central role in higher-order chromosome structure in all kingdoms of life [1–5]. SMC proteins consist of a long coiled-coil domain that joins an ATP binding cassette (ABC) ATPase domain on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecd83950711817be0f9f3a3aad65b38
https://pubmed.ncbi.nlm.nih.gov/15458651
https://pubmed.ncbi.nlm.nih.gov/15458651
Autor:
Katja Sträßer, Sophia Hartung, Carolin Möckel, Emanuel Clausing, Derk J. Bemeleit, María Lucas, Christian B. Schiller, Alexandra Schele, Karl-Peter Hopfner, Katja Lammens, Christof Angermüller, Johannes Söding
Publikováno v:
Cell
Cell 145, 54-66 (2011). doi:10.1016/j.cell.2011.02.038
Cell 145, 54-66 (2011). doi:10.1016/j.cell.2011.02.038
Summary The MR ( M re11 nuclease and R ad50 ABC ATPase) complex is an evolutionarily conserved sensor for DNA double-strand breaks, highly genotoxic lesions linked to cancer development. MR can recognize and process DNA ends even if they are blocked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e9c4a2916ab3742bb61701d052675a