Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alexandra Schebesta"'
Autor:
Liisa Andersen, Alexandra Franziska Gülich, Marlis Alteneder, Teresa Preglej, Maria Jonah Orola, Narendra Dhele, Valentina Stolz, Alexandra Schebesta, Patricia Hamminger, Anastasiya Hladik, Stefan Floess, Thomas Krausgruber, Thomas Faux, Syed Bilal Ahmad Andrabi, Jochen Huehn, Sylvia Knapp, Tim Sparwasser, Christoph Bock, Asta Laiho, Laura L. Elo, Omid Rasool, Riitta Lahesmaa, Shinya Sakaguchi, Wilfried Ellmeier
Publikováno v:
Cell Reports, Vol 29, Iss 13, Pp 4447-4459.e6 (2019)
Summary: Forkhead box protein P3+ (FOXP3+) regulatory T cells (Treg cells) play a key role in maintaining tolerance and immune homeostasis. Here, we report that a T cell-specific deletion of the transcription factor MAZR (also known as PATZ1) leads t
Externí odkaz:
https://doaj.org/article/974129bdad3742e980b60d2cd2ed4c8c
Autor:
Anastasia Abramova, Shinya Sakaguchi, Alexandra Schebesta, Hammad Hassan, Nicole Boucheron, Peter Valent, Axel Roers, Wilfried Ellmeier
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77677 (2013)
Mast cells are key players in type I hypersensitivity reactions in humans and mice and their activity has to be tightly controlled. Previous studies implicated the transcription factor MAZR in the regulation of mast cell function. To study the role o
Externí odkaz:
https://doaj.org/article/e47d6837ac684f27b0b67a8f599e1464
Autor:
Lisa Sandner, Marlis Alteneder, Ramona Rica, Barbara Woller, Eleonora Sala, Tobias Frey, Anela Tosevska, Ci Zhu, Moritz Madern, Pol Hoffmann, Alexandra Schebesta, Ichiro Taniuchi, Michael Bonelli, Klaus Schmetterer, Matteo Iannacone, Mirela Kuka, Wilfried Ellmeier, Shinya Sakaguchi, Ruth Herbst, Nicole Boucheron
T follicular helper (Tfh) cells are essential for the development of germinal center B cells and high-affinity antibody producing B-cells in human and mice. Here, we identify the guanine nucleotide exchange factor (GEF) Rin-like (Rinl) as a negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98f220eaec046b889f50abf0fee3e14e
https://doi.org/10.1101/2022.06.23.497284
https://doi.org/10.1101/2022.06.23.497284
Autor:
Omid Rasool, Thomas Faux, Anastasiya Hladik, Teresa Preglej, Syed Bilal Ahmad Andrabi, Thomas Krausgruber, Asta Laiho, Patricia Hamminger, Alexandra Franziska Gülich, Wilfried Ellmeier, Narendra Dhele, Liisa Andersen, Alexandra Schebesta, Sylvia Knapp, Stefan Floess, Maria Jonah Orola, Christoph Bock, Laura L. Elo, Jochen Huehn, Valentina Stolz, Shinya Sakaguchi, Riitta Lahesmaa, Marlis Alteneder, Tim Sparwasser
Publikováno v:
Cell Reports, Vol 29, Iss 13, Pp 4447-4459.e6 (2019)
Cell reports
Cell reports
Summary: Forkhead box protein P3+ (FOXP3+) regulatory T cells (Treg cells) play a key role in maintaining tolerance and immune homeostasis. Here, we report that a T cell-specific deletion of the transcription factor MAZR (also known as PATZ1) leads t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f64a342b38c32dece30dfa10e7f2d8
http://www.sciencedirect.com/science/article/pii/S2211124719315876
http://www.sciencedirect.com/science/article/pii/S2211124719315876
Autor:
Markus Jaritz, Alexandra Schebesta, Qiong Sun, Hiromi Tagoh, Tanja A. Schwickert, Maria Fischer, Anja Ebert, Luisa Cochella, Adrian Liston, Chiara Alberti, Lesly Calderón, Meinrad Busslinger, Martina Minnich, Stephen Malin, Karina Schindler
Publikováno v:
Sci Immunol
The transcription factor Pax5 controls B cell development, but its role in mature B cells is largely enigmatic. Here, we demonstrated that the loss of Pax5 by conditional mutagenesis in peripheral B lymphocytes led to the strong reduction of B-1a, ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9242dbdcec0cb05301d22528204573
https://doi.org/10.1126/sciimmunol.abg5003
https://doi.org/10.1126/sciimmunol.abg5003
Autor:
Liisa, Andersen, Alexandra Franziska, Gülich, Marlis, Alteneder, Teresa, Preglej, Maria Jonah, Orola, Narendra, Dhele, Valentina, Stolz, Alexandra, Schebesta, Patricia, Hamminger, Anastasiya, Hladik, Stefan, Floess, Thomas, Krausgruber, Thomas, Faux, Syed Bilal Ahmad, Andrabi, Jochen, Huehn, Sylvia, Knapp, Tim, Sparwasser, Christoph, Bock, Asta, Laiho, Laura L, Elo, Omid, Rasool, Riitta, Lahesmaa, Shinya, Sakaguchi, Wilfried, Ellmeier
Publikováno v:
Cell reports. 29(13)
Forkhead box protein P3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f93b832ac9e9aca3c4437ff7a64ba45
https://pubmed.ncbi.nlm.nih.gov/31875552
https://pubmed.ncbi.nlm.nih.gov/31875552
Publikováno v:
FEBS Journal. 278:1990-2000
Mast cells express the high-affinity receptor for IgE (FceRI) and are key players in type I hypersensitivity reactions. They are critically involved in the development of allergic rhinitis, allergic asthma and systemic anaphylaxis, however, they also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0977d91eb68b3fe7f9b270047bc1b33
https://doi.org/10.1111/j.1742-4658.2011.08073.x
https://doi.org/10.1111/j.1742-4658.2011.08073.x
Autor:
Harald Herrmann, Margit Weghofer, Giulio Superti-Furga, Keiryn L. Bennett, Wilfried Ellmeier, Uwe Rix, Michael Kneidinger, Christian Lupinek, Peter Valent, Wayne R. Thomas, Anja Vales, Francis Y. Lee, Susanne Vrtala, Karoline V. Gleixner, Uwe Schmidt, Rudolf Valenta, Alexandra Schebesta, Christian Baumgartner
Publikováno v:
Blood. 111:3097-3107
Dasatinib is a multitargeted drug that blocks several tyrosine kinases. Apart from its well-known antileukemic activity, the drug has attracted attention because of potential immunosuppressive and anti-inflammatory effects. We report that dasatinib a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc93574b9b3a19f78c533a9e00afb30
https://doi.org/10.1182/blood-2007-08-104372
https://doi.org/10.1182/blood-2007-08-104372
Autor:
Anna Berglöf, K. Emelie M. Blomberg, Shinya Sakaguchi, Julia Raberger, Thomas Kolbe, Wilfried Ellmeier, Thomas Rülicke, Nicole Boucheron, Alexandra Schebesta, C. I. Edvard Smith
Publikováno v:
Proceedings of the National Academy of Sciences; Vol 105
Transcriptional pathways controlling the development of CD44 hi memory phenotype (MP) T cells with “innate-like” functions are not well understood. Here we show that the BTB (bric-a-brac, tramtrack, broad complex) domain-containing protein promye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd18e78c832a0818f4bc19f7d8de8609
Autor:
Shane McManus, Giorgia Salvagiotto, Alessio Delogu, Alexandra Schebesta, Georg A. Busslinger, Meinrad Busslinger
Publikováno v:
Immunity. 27(1):49-63
SummaryThe transcription factor Pax5 represses B lineage-inappropriate genes and activates B cell-specific genes in B lymphocytes. Here we have identified 170 Pax5-activated genes. Conditional mutagenesis demonstrated that the Pax5-regulated genes re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b12f6a08f9e5c6c57c9a2c816f1b35