Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alexandra Santanach"'
Autor:
Mar González-Ramírez, Cecilia Ballaré, Francesca Mugianesi, Malte Beringer, Alexandra Santanach, Enrique Blanco, Luciano Di Croce
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009368 (2021)
The ChIP-seq signal of histone modifications at promoters is a good predictor of gene expression in different cellular contexts, but whether this is also true at enhancers is not clear. To address this issue, we develop quantitative models to charact
Externí odkaz:
https://doaj.org/article/415ee9a20d154851a028a154237d912c
Autor:
Alexandra Santanach, Enrique Blanco, Hua Jiang, Kelly R. Molloy, Miriam Sansó, John LaCava, Lluis Morey, Luciano Di Croce
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
In mammals, five different CBX proteins can be part of Polycomb repressive complex 1 (PRC1). Here, the authors provide evidence that CBX6 plays an essential role in regulating pluripotency in embryonic stem cells and that CBX6 functions as part of bo
Externí odkaz:
https://doaj.org/article/cf337e53504d4dbca5db1c546d985bc4
Autor:
Enrique Blanco, Lluis Morey, Miriam Sansó, Hua Jiang, John LaCava, Alexandra Santanach, Luciano Di Croce, Kelly R. Molloy
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications
Recercat. Dipósit de la Recerca de Catalunya
instname
Polycomb group proteins (PcG) are transcriptional repressors that control cell identity and development. In mammals, five different CBX proteins associate with the core Polycomb repressive complex 1 (PRC1). In mouse embryonic stem cells (ESCs), CBX6
Autor:
Pascal W.T.C. Jansen, Susan L. Kloet, H. Irem Baymaz, Alexandra Santanach, Lisa van Voorthuijsen, Michiel Vermeulen, Ino D Karemaker, Luciano Di Croce, Matthew M. Makowski
Publikováno v:
Nature Structural & Molecular Biology, 23, 682-90
Nature structural & molecular biology
Nature Structural & Molecular Biology, 23, 7, pp. 682-90
Nature structural & molecular biology
Nature Structural & Molecular Biology, 23, 7, pp. 682-90
Although the core subunits of Polycomb group (PcG) complexes are well characterized, little is known about the dynamics of these protein complexes during cellular differentiation. We used quantitative interaction proteomics and genome-wide profiling
Autor:
Luigi Aloia, Alexandra Santanach, Enrique Blanco, Luciano Di Croce, Elphège P. Nora, Lluis Morey, Benoit G. Bruneau
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
instname
Polycomb complexes (PRC1 and PRC2) are essential regulators of epigenetic gene silencing in embryonic and adult stem cells. Emerging evidence suggests that the core subunit composition regulates distinct biological processes, yet little is known abou
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
instname
Embryonic stem cells (ESCs) are characterized by their ability to self-renew and to differentiate into all cell types of a given organism. Understanding the molecular mechanisms that govern the ESC state is of great interest not only for basic resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c907c16937d0220da347ba751b74148e
http://hdl.handle.net/10230/27117
http://hdl.handle.net/10230/27117