Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexandra R. Frank"'
Autor:
Alexandra N. Heinloth, William K. Kaufmann, Timothy P. Heffernan, Richard S. Paules, Alexandra R. Frank, Marila Cordeiro-Stone, Dennis A. Simpson
Publikováno v:
Molecular and Cellular Biology. 22:8552-8561
Accurate replication and segregation of the human genome depends on interactions between cell cycle checkpoints and pathways of DNA repair. Cell cycle checkpoints are biochemical surveillance pathways that slow or arrest progression through the cell
Autor:
Marila Cordeiro-Stone, Lisa D. McDaniel, Miriam F. Bryant, William K. Kaufmann, Stephanie B. Hatch, Ikechukwu Oguejiofor, Alexandra R. Frank
Publikováno v:
Carcinogenesis. 23:959-966
Lack of DNA polymerase eta and the attendant defect in bypass replication of pyrimidine dimers induced in DNA by ultraviolet light (UV) underlie the enhanced mutagenesis and carcinogenesis observed in xeroderma pigmentosum variant (XP-V). We investig
Autor:
Yingchun Zhou, Nana Nikolaishvili-Feinberg, Marila Cordeiro-Stone, William K. Kaufmann, Miriam F. Bryant, Alexandra R. Frank, Lea M. Beaulieu, Douglas D. Luche, Timothy P. Heffernan, Sharon C. Doherty, Tong Zhou, Dennis A. Simpson
Publikováno v:
Mutation research. 532(1-2)
The ability of caffeine to reverse cell cycle checkpoint function and enhance genotoxicity after DNA damage was examined in telomerase-expressing human fibroblasts. Caffeine reversed the ATM-dependent S and G2 checkpoint responses to DNA damage induc
Publikováno v:
American journal of respiratory and critical care medicine. 159(3)
Tracheal gas insufflation (TGI) decreases dead space (V D) and can be combined with continuous positive airway pressure (CPAP) to decrease minute volume (VE) and effort of breathing. In 11 anesthetized sheep, we induced acute lung injury (ALI) throug