Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Alexandra R. Fernandes"'
Publikováno v:
Cancer Nanotechnology, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Background The delivery of therapeutic nucleic acids, such as small interfering RNA (siRNA) and antisense oligonucleotides (ASO) into cells, is widely used in gene therapy. Gold nanoparticles (AuNPs) have proved to be effective in delivering
Externí odkaz:
https://doaj.org/article/7d4c069a376c45f1806b063c1c12eba4
Autor:
João Paquete-Ferreira, Filipe Freire, Henrique S. Fernandes, Jayaraman Muthukumaran, João Ramos, Joana Bryton, Alejandro Panjkovich, Dmitri Svergun, Marino F. A. Santos, Márcia A. S. Correia, Alexandra R. Fernandes, Maria João Romão, Sérgio F. Sousa, Teresa Santos-Silva
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
The rise of antibiotic-resistant bacterial strains has become a critical health concern. According to the World Health Organization, the market introduction of new antibiotics is alarmingly sparse, underscoring the need for novel therapeutic targets.
Externí odkaz:
https://doaj.org/article/b1afbc1999ca4af7b429362c5b94d621
Autor:
Elisabete Muchagato Maurício, Patrícia Branco, Ana Luiza Barros Araújo, Catarina Roma-Rodrigues, Katelene Lima, Maria Paula Duarte, Alexandra R. Fernandes, Helena Albergaria
Publikováno v:
Antibiotics, Vol 13, Iss 9, p 881 (2024)
Biotechnological active peptides are gaining interest in the cosmetics industry due to their antimicrobial, anti-inflammatory, antioxidant, and anti-collagenase (ACE) effects, as well as wound healing properties, making them suitable for cosmetic for
Externí odkaz:
https://doaj.org/article/b21c344ddced4b4b8bdad07b6e3eb93c
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Three-dimensional (3D) cell culture using tumor spheroids provides a crucial platform for replicating tissue microenvironments. However, effective gene modulation via nanoparticle-based transfection remains a challenge, often facing delivery hurdles.
Externí odkaz:
https://doaj.org/article/a7545bb6da9a47b282f844bcedb2a0b4
Autor:
Ruben Valente, Sandra Cordeiro, André Luz, Maria C. Melo, Catarina Roma Rodrigues, Pedro V. Baptista, Alexandra R. Fernandes
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: The research on tumor microenvironment (TME) has recently been gaining attention due to its important role in tumor growth, progression, and response to therapy. Because of this, the development of three-dimensional cancer models that m
Externí odkaz:
https://doaj.org/article/24c8239f46a74b2fb4d7fbdf39124b84
Autor:
Sofia Friães, Cândida Trigueiros, Clara S. B. Gomes, Alexandra R. Fernandes, Oscar A. Lenis-Rojas, Marta Martins, Beatriz Royo
Publikováno v:
Molecules, Vol 28, Iss 21, p 7453 (2023)
Background. Antimicrobial resistance is one of the most pressing health issues of our time. The increase in the number of antibiotic-resistant bacteria allied to the lack of new antibiotics has contributed to the current crisis. It has been predicted
Externí odkaz:
https://doaj.org/article/a468db2ddf5641dbbcec52f543a2f405
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/436ef4e81b1b47cea683417cc941e5fc
Autor:
Patrícia Branco, Elisabete Muchagato Maurício, Ana Costa, Diogo Ventura, Catarina Roma-Rodrigues, Maria Paula Duarte, Alexandra R. Fernandes, Catarina Prista
Publikováno v:
Antibiotics, Vol 12, Iss 8, p 1332 (2023)
The rising demand for minimally processed, natural, and healthier food products has led to the search for alternative and multifunctional bioactive food components. Therefore, the present study focuses on the functional proprieties of a peptide fract
Externí odkaz:
https://doaj.org/article/013b2b80f39f48aea2916b236d0f40c6
Autor:
Diana Araújo, Matilde Martins, Patrícia Concórdio-Reis, Catarina Roma-Rodrigues, Maria Morais, Vítor D. Alves, Alexandra R. Fernandes, Filomena Freitas
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 991 (2023)
FucoPol, a fucose-rich polyanionic polysaccharide, was used for the first time for the preparation of hydrogel membranes (HMs) using Fe3+ as a crosslinking agent. This study evaluated the impact of Fe3+ and FucoPol concentrations on the HMs’ streng
Externí odkaz:
https://doaj.org/article/c86503366f34446293d705554cda1a68
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Streptococcus dysgalactiae (SD) is capable of infecting both humans and animals and causing a wide range of invasive and non-invasive infections. With two subspecies, the taxonomic status of subspecies of SD remains controversial. Subspecies equisimi
Externí odkaz:
https://doaj.org/article/a6d4c25057b34959857cbf4470e9c813