Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Alexandra R. De Leon"'
Autor:
Andrew J. Kennedy, James E. East, Timothy L. Macdonald, Kevin R. Lynch, Jose L. Tomsig, Alexandra R. De Leon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:7132-7136
Autotaxin (ATX) is a secreted soluble enzyme that generates lysophosphatidic acid (LPA) through its lysophospholipase D activity. Because of LPA’s role in neoplastic diseases, ATX is an attractive therapeutic target due to its involvement in LPA bi