Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alexandra Piunti"'
Autor:
Gaelle R. Carrat, Elizabeth Haythorne, Alejandra Tomas, Leena Haataja, Andreas Müller, Peter Arvan, Alexandra Piunti, Kaiying Cheng, Mutian Huang, Timothy J. Pullen, Eleni Georgiadou, Theodoros Stylianides, Nur Shabrina Amirruddin, Victoria Salem, Walter Distaso, Andrew Cakebread, Kate J. Heesom, Philip A. Lewis, David J. Hodson, Linford J. Briant, Annie C.H. Fung, Richard B. Sessions, Fabien Alpy, Alice P.S. Kong, Peter I. Benke, Federico Torta, Adrian Kee Keong Teo, Isabelle Leclerc, Michele Solimena, Dale B. Wigley, Guy A. Rutter
Publikováno v:
Molecular Metabolism, Vol 40, Iss , Pp 101015- (2020)
Objective: Risk alleles for type 2 diabetes at the STARD10 locus are associated with lowered STARD10 expression in the β-cell, impaired glucose-induced insulin secretion, and decreased circulating proinsulin:insulin ratios. Although likely to serve
Externí odkaz:
https://doaj.org/article/075506f07a044c31be2e44b42ccc2527
Autor:
Theodoros Stylianides, Fabien Alpy, Peter I. Benke, Alexandra Piunti, Victoria Salem, Michele Solimena, Alejandra Tomas, David J. Hodson, Andrew Cakebread, Andreas Müller, Kate J. Heesom, Nur Shabrina Amirruddin, Federico Torta, Isabelle Leclerc, Leena Haataja, Peter Arvan, Timothy J. Pullen, Annie C. H. Fung, Linford J.B. Briant, Kaiying Cheng, Gaelle Carrat, Alice P.S. Kong, Dale B. Wigley, Philip A. Lewis, Richard B. Sessions, Elizabeth Haythorne, Mutian Huang, Adrian Kee Keong Teo, Guy A. Rutter, Eleni Georgiadou, Walter Distaso
Publikováno v:
Molecular Metabolism
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 40, pp.101015. ⟨10.1016/j.molmet.2020.101015⟩
bioRxiv
Molecular metabolism, 2020, 40, pp.101015. ⟨10.1016/j.molmet.2020.101015⟩
Molecular Metabolism, Vol 40, Iss, Pp 101015-(2020)
Carrat, G, Haythorne, E, Tomas, A, Haataja, L, Muller, A, Arvan, P, Piunti, A, Cheng, K, Huang, M, Pullen, T J, Georgiadou, E, Stylianides, T, Amirruddin, N S, Salem, V, Distaso, W, Cakebread, A, Heesom, K J, Lewis, P A, Hodson, D J, Briant, L J B, Fung, A, Sessions, R B, Alpy, F, Kong, A, Benke, P, Torta, F, Keong Teo, A K, Leclerc, I, Solimena, M, Wigley, DB & Rutter, G A 2020, ' The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis ', Molecular metabolism, vol. 40, 101015 . https://doi.org/10.1016/j.molmet.2020.101015
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 40, pp.101015. ⟨10.1016/j.molmet.2020.101015⟩
bioRxiv
Molecular metabolism, 2020, 40, pp.101015. ⟨10.1016/j.molmet.2020.101015⟩
Molecular Metabolism, Vol 40, Iss, Pp 101015-(2020)
Carrat, G, Haythorne, E, Tomas, A, Haataja, L, Muller, A, Arvan, P, Piunti, A, Cheng, K, Huang, M, Pullen, T J, Georgiadou, E, Stylianides, T, Amirruddin, N S, Salem, V, Distaso, W, Cakebread, A, Heesom, K J, Lewis, P A, Hodson, D J, Briant, L J B, Fung, A, Sessions, R B, Alpy, F, Kong, A, Benke, P, Torta, F, Keong Teo, A K, Leclerc, I, Solimena, M, Wigley, DB & Rutter, G A 2020, ' The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis ', Molecular metabolism, vol. 40, 101015 . https://doi.org/10.1016/j.molmet.2020.101015
Objective Risk alleles for type 2 diabetes at the STARD10 locus are associated with lowered STARD10 expression in the β-cell, impaired glucose-induced insulin secretion, and decreased circulating proinsulin:insulin ratios. Although likely to serve a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee31ae299bb38311feeaf4ba6eff987
http://hdl.handle.net/10044/1/80098
http://hdl.handle.net/10044/1/80098
Autor:
Fabien Alpy, Elizabeth Haythorne, D J Hodson, Alexandra Piunti, Alice P. Kong, Gaelle Carrat, Isabelle Leclerc, Eleni Georgiadou, Timothy J. Pullen, Annie C. Fung, Peter Arvan, Victoria Salem, Andrew Cakebread, Alejandra Tomas, Walter Distaso, Theodoros Stylianides, Richard B. Sessions, Leena Haataja, Guy A. Rutter
Publikováno v:
Diabetes. 68
Aim: Risk alleles for type 2 diabetes (T2D) in the STARD10 locus, impair insulin secretion and are associated with decreased proinsulin:insulin ratios. We have shown that the T2D risk associated with variation at this locus is likely to be mediated t