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NMR structure and action on nicotinic acetylcholine receptors of water-soluble domain of human LYNX1
Autor:
Alexandra P. Krivolapova, Victor I. Tsetlin, Ekaterina N. Lyukmanova, Dmitry A. Dolgikh, Konstantin S. Mineev, Mikhail A. Shulepko, Vladimir Dolezal, Sergey Yu. Filkin, Mikhail P. Kirpichnikov, Helena Janickova, Zakhar O. Shenkarev, Dieter D’hoedt, Igor E. Kasheverov, Daniel Bertrand, Alexander S. Arseniev
Publikováno v:
Journal of Biological Chemistry; Vol 286
Discovery of proteins expressed in the central nervous system sharing the three-finger structure with snake α-neurotoxins provoked much interest to their role in brain functions. Prototoxin LYNX1, having homology both to Ly6 proteins and three-finge