Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alexandra Ohs"'
Publikováno v:
Cells, Vol 11, Iss 1, p 149 (2022)
Nephronectin (NPNT) is an extracellular matrix protein in the glomerular basement membrane that is produced by podocytes and is important for the integrity of the glomerular filtration barrier. Upregulated transforming growth factor β (TGF-β) and a
Externí odkaz:
https://doaj.org/article/b0226851d81240faa5f5e7e7760606c5
Autor:
Raluca Ursu, Nina Sopel, Alexandra Ohs, Ramesh Tati, Lisa Buvall, Jenny Nyström, Mario Schiffer, Janina Müller-Deile
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15070
Deciphering the pathophysiological mechanisms of primary podocytopathies that can lead to end-stage renal disease and increased mortality is an unmet need. Studying how microRNAs (miRs) interfere with various signaling pathways enables identification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c760b16d49f68a40da5b3e8faefc71d
Autor:
Janina Müller-Deile, Victoria Rose, Jan Hegermann, Christoph Daniel, Kerstin Amann, Marwin Gröner, Mario Schiffer, Nina Sopel, Alexandra Ohs, Christoph Wrede, Gunther Zahner
Publikováno v:
J Am Soc Nephrol
Background Autoantibodies binding to podocyte antigens cause idiopathic membranous glomerulonephritis (iMGN). However, it remains elusive how autoantibodies reach the subepithelial space because the glomerular filtration barrier (GFB) is size selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c808ba1e58f1854cc5584bc3252156
https://doi.org/10.1681/asn.2020121699
https://doi.org/10.1681/asn.2020121699
Autor:
Victoria Rose, Nina Sopel, Alexandra Ohs, Christina Warnecke, Mario Schiffer, Janina Müller-Deile
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Genetic focal segmental glomerulosclerosis (FSGS) is related to irreversible damage of the filtration barrier and podocyte effacement. More than 40 genes with mutations, involved in slit diaphragm formation, actin cytoskeleton syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1729a2859aee3d9f7841c8341fe9f016
https://doi.org/10.1093/ndt/gfac104.002
https://doi.org/10.1093/ndt/gfac104.002
Autor:
Victoria Rose, Janina Müller-Deile, Nina Sopel, Alexandra Ohs, Christina Warnecke, Mario Schiffer
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims The smallest filtration unit of the kidney, the glomerulus, is composed of capillaries formed by glomerular endothelial cells (GEC), glomerular basement membrane and podocytes. Furthermore, glomerular mesangial cells (GMC) between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28258e806f52e18385e4bfd4644d9297
https://doi.org/10.1093/ndt/gfab079.001
https://doi.org/10.1093/ndt/gfab079.001
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims The glomerular basement membrane (GBM), podocytes and glomerular endothelial cells (GEC) are composing the glomerular filtration barrier (GFB) within the glomerulus. Both podocytes and GEC are essential components for the synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::882c0110d9ec04b0774ba16320645241
https://doi.org/10.1093/ndt/gfab079.007
https://doi.org/10.1093/ndt/gfab079.007
Autor:
Andreas Feigenspan, Alexandra Ohs, Johann Helmut Brandstätter, Julia von Wittgenstein, Norbert Babai
Publikováno v:
Experimental eye research. 195
Expression patterns of voltage-gated ion channels determine the spatio-temporal dynamics of ion currents that supply excitable neurons in developing tissue with proper electrophysiological properties. The purpose of the study was to identify fast cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7e4e29a0fa68a8b72747384703881a
https://pubmed.ncbi.nlm.nih.gov/32277973
https://pubmed.ncbi.nlm.nih.gov/32277973
Autor:
Alexandra Ohs, Daniel R. Engel, Wolfgang Baum, Stefan Landgraeber, Astrid M. Westendorf, Oliver Kraff, Alexandra Brenzel, Gerhard Krönke, Lasse Kling, Jens V. Stein, Alexandra Adamczyk, Marcel Dudda, Thomas Kamradt, Manfred Rohde, Matthias Gunzer, Stefanie C. Lang, Daniela Weidner, Daniel Hoffmann, Georg Schett, Anja Hasenberg, Silke Christiansen, Martin Herrmann, Ibrahim Hawwari, Sylvia Müller, Sylvia Voortmann, Stephan Culemann, Renzo Danuser, Andrea Vortkamp, Annette I. Garbe, Anika Grüneboom, Sophie Henneberg, Simon F. Merz, Marcus Jäger, Kristina Zec, Harald H. Quick, Lea Bornemann, Manuela Wuelling, Kolja Gelse, Mike Hasenberg
Publikováno v:
Nature metabolism
International
Germany
Nature Metabolism
International
Germany
Nature Metabolism
Closed circulatory systems underlie the function of vertebrate organs, but in long bones their structure is unclear although they constitute the exit route for bone marrow (BM) leukocytes. To understand neutrophil migration from BM, we studied the va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77daec4a2937d62c48f2a4612ea431a6
https://pubmed.ncbi.nlm.nih.gov/31620676
https://pubmed.ncbi.nlm.nih.gov/31620676