Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Alexandra Neyazi"'
Autor:
Hannah Benedictine Maier, Alexandra Neyazi, Gabriel L. Bundies, Fiona Meyer-Bockenkamp, Stefan Bleich, Hansi Pathak, Yvonne Ziert, Barbara Neuhaus, Franz-Josef Müller, Iris Pollmann, Thomas Illig, Stefanie Mücke, Meike Müller, Brinja Kira Möller, Steffen Oeltze-Jafra, Tim Kacprowski, Jan Voges, Fabian Müntefering, Josef Scheiber, Andreas Reif, Mareike Aichholzer, Christine Reif-Leonhard, Maren Schmidt-Kassow, Ulrich Hegerl, Hanna Reich, Stefan Unterecker, Heike Weber, Jürgen Deckert, Nicole Bössel-Debbert, Hans J. Grabe, Michael Lucht, Helge Frieling
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Brain-derived neurotrophic factor (BDNF) is essential for antidepressant treatment of major depressive disorder (MDD). Our repeated studies suggest that DNA methylation of a specific CpG site in the promoter region of exon IV of t
Externí odkaz:
https://doaj.org/article/55ea2c6790ba48b2a005ed3270692acc
Autor:
Franz Felix Konen, Hannah Benedictine Maier, Alexandra Neyazi, Stefan Bleich, Konstantin Neumann, Thomas Skripuletz
Publikováno v:
Neurological Research and Practice, Vol 5, Iss 1, Pp 1-12 (2023)
Abstract Background Alzheimer´s disease is considered a neurodegenerative disease and is diagnosed by exclusion, while the detection of specific cerebrospinal fluid (CSF) biomarkers, namely amyloid-beta (Aβ) peptides Aβ1–42 (Aß42), phospho-tau
Externí odkaz:
https://doaj.org/article/fa8c03f6b11a4056bab65e175268bd35
Autor:
Deepti Singh, Paul C. Guest, Henrik Dobrowolny, Veronika Vasilevska, Gabriela Meyer-Lotz, Hans-Gert Bernstein, Katrin Borucki, Alexandra Neyazi, Bernhard Bogerts, Roland Jacobs, Johann Steiner
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-12 (2022)
Abstract Background We recently reported increased levels of neutrophils, monocytes and C-reactive protein (CRP) correlated with symptom severity in acute schizophrenia. Here, we investigated if a similar pattern of innate immune system activation oc
Externí odkaz:
https://doaj.org/article/6e6bcd82d07c4aae8b26996f2540f126
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background Systematic technical effects—also called batch effects—are a considerable challenge when analyzing DNA methylation (DNAm) microarray data, because they can lead to false results when confounded with the variable of interest. M
Externí odkaz:
https://doaj.org/article/9bdd1df4c2cb4401acb3371ffad31123
Autor:
Stefan Gingele, Moritz Koch, Anna Christina Saparilla, Gudrun M. Körner, Jarle von Hörsten, Marina Gingele, Tabea Seeliger, Franz Felix Konen, Martin W. Hümmert, Alexandra Neyazi, Martin Stangel, Thomas Skripuletz
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 14 (2021)
Background: IgPro20 is the first approved subcutaneous immunoglobulin (SCIg) preparation for the treatment of patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Two different doses of the SCIg preparation were investigated in the
Externí odkaz:
https://doaj.org/article/76e35fded0cb4807b1a6b662c7f53955
Autor:
Niels Hansen, Michael Lipp, Jonathan Vogelgsang, Ruth Vukovich, Tristan Zindler, Daniel Luedecke, Stefan Gingele, Berend Malchow, Helge Frieling, Simone Kühn, Johannes Denk, Jürgen Gallinat, Thomas Skripuletz, Nicole Moschny, Jens Fiehler, Christian Riedel, Klaus Wiedemann, Mike P. Wattjes, Inga Zerr, Hermann Esselmann, Stefan Bleich, Jens Wiltfang, Alexandra Neyazi
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 9, Iss , Pp 100154- (2020)
Background: Autoimmune-mediated encephalitis is a disease that often encompasses psychiatric symptoms as its first clinical manifestation’s predominant and isolated characteristic. Novel guidelines even distinguish autoimmune psychosis from autoimm
Externí odkaz:
https://doaj.org/article/492aed4140b143cfa58a507c7af5a953
Autor:
Nicole Moschny, Kirsten Jahn, Malek Bajbouj, Hannah Benedictine Maier, Matthias Ballmaier, Abdul Qayyum Khan, Christoph Pollak, Stefan Bleich, Helge Frieling, Alexandra Neyazi
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
BackgroundMajor depressive disorder (MDD) represents a tremendous health threat to the world’s population. Electroconvulsive therapy (ECT) is the most effective treatment option for refractory MDD patients. Ample evidence suggests brain-derived neu
Externí odkaz:
https://doaj.org/article/02b9033e0f3045738afc458aa153d9e7
Autor:
Philipp Schwenkenbecher, Theda Janssen, Ulrich Wurster, Felix Franz Konen, Alexandra Neyazi, Jonas Ahlbrecht, Wolfram Puppe, Lena Bönig, Kurt-Wolfram Sühs, Martin Stangel, Tina Ganzenmueller, Thomas Skripuletz
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Background: Blood contamination due to traumatic lumbar puncture presents a diagnostic pitfall in cerebrospinal fluid (CSF) analysis. It is controversially discussed if phagocytosis of erythrocytes which can be found in the CSF after subarachnoid hem
Externí odkaz:
https://doaj.org/article/140ab1f5f54a4c619b696d8e44acbf01
Autor:
Alexandra Neyazi, Vanessa Buchholz, Alexandra Burkert, Thomas Hillemacher, Martina de Zwaan, Wolfgang Herzog, Kirsten Jahn, Katrin Giel, Stephan Herpertz, Christian A. Buchholz, Andreas Dinkel, Markus Burgmer, Almut Zeeck, Stefan Bleich, Stephan Zipfel, Helge Frieling
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Epigenetic alterations are increasingly implicated in the pathophysiology of anorexia nervosa (AN) but are as yet poorly understood. We investigated possible associations between the leptin gene (LEP) and the leptin receptor gene (LEPR) DNA promoter
Externí odkaz:
https://doaj.org/article/4fe4dcbc19f947cba909db1090cde247
Autor:
Klaus Lieb, Nadine Dreimüller, Stefanie Wagner, Konrad Schlicht, Tanja Falter, Alexandra Neyazi, Linda Müller-Engling, Stefan Bleich, André Tadić, Helge Frieling
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
Major problems of current antidepressant pharmacotherapy are insufficient response rates and difficulties in response prediction. We recently provided preliminary evidence in a small study that patients with major depressive disorder (MDD) with a hyp
Externí odkaz:
https://doaj.org/article/bb595a9bfe9b4b58b540a0c725ab6e21