Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alexandra N. Brown-Suedel"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Caspase-2 belongs to the caspase family of proteins responsible for essential cellular functions including apoptosis and inflammation. Uniquely, caspase-2 has been identified as a tumor suppressor, but how it regulates this function is still unknown.
Externí odkaz:
https://doaj.org/article/9466b48185934da695aaf927fbaedded
Autor:
Dharaniya Sakthivel, Alexandra N. Brown-Suedel, Francesca Keane, Shixia Huang, Kenneth Mc Sherry, Chloé I Charendoff, Kevin P. Dunne, Dexter J Robichaux, BaoChau Le, Crystal S. Shin, Alexandre F Carisey, Jonathan M. Flanagan, Lisa Bouchier-Hayes
Publikováno v:
bioRxiv
Mutation in nucleophosmin (NPM1) causes relocalization of this normally nucleolar protein to the cytoplasm (NPM1c+). Despite NPM1 mutation being the most common driver mutation in cytogenetically normal adult acute myeloid leukemia (AML), the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068057070548de56646af1a6eb36ab5b
https://doi.org/10.1101/2023.05.29.542723
https://doi.org/10.1101/2023.05.29.542723
Autor:
Alexandra N Brown-Suedel, Vanda Yazdani, Chloé I. Charendoff, Jonathan M. Flanagan, Gregory M. Vercellotti, Lisa Bouchier-Hayes, Beatriz E. Bolívar, Brittany A. Rohrman, John D. Belcher
Publikováno v:
J Immunol
Excessive release of heme from RBCs is a key pathophysiological feature of several disease states, including bacterial sepsis, malaria, and sickle cell disease. This hemolysis results in an increased level of free heme that has been implicated in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae64ad7b2b8eac32d68558edfa606ffe
https://pubmed.ncbi.nlm.nih.gov/33741688
https://pubmed.ncbi.nlm.nih.gov/33741688