Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alexandra N Mills"'
Autor:
Tiziana Petrozziello, Amanda M Dios, Kaly A Mueller, Christine A Vaine, William T Hendriks, Kelly E Glajch, Alexandra N Mills, Kotchaphorn Mangkalaphiban, Ellen B Penney, Naoto Ito, Cara Fernandez-Cerado, Gierold Paul A Legarda, M Salvie Velasco-Andrada, Patrick J Acuña, Mark A Ang, Edwin L Muñoz, Cid Czarina E Diesta, Regina Macalintal-Canlas, Geraldine Acuña, Nutan Sharma, Laurie J Ozelius, D Cristopher Bragg, Ghazaleh Sadri-Vakili
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243655 (2020)
X-linked Dystonia-Parkinsonism (XDP) is a neurodegenerative disease linked to an insertion of a SINE-VNTR-Alu (SVA)-type retrotransposon within an intron of TAF1. This SVA insertion induces aberrant TAF1 splicing and partial intron retention, thereby
Externí odkaz:
https://doaj.org/article/589a61b80bba4eb7bc6d53099ba584bd
Autor:
Jacquelyn Dillon, Alexandra N Mills, Kate R Pawloski, Nicholas Scribetta, Alexander Greenstein
Publikováno v:
Journal of Surgical Case Reports. 2023
Self-expandable metal stent (SEMS) are widely utilized as a bridge to surgical intervention and for palliative treatment of malignant bowel obstructions. The risk of complications associated with SEMS is low in well-selected patients. Stent erosion i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab421bdbcfdf95a1c62b4f0192e09746
https://doi.org/10.1093/jscr/rjac615
https://doi.org/10.1093/jscr/rjac615
Autor:
James D. Berry, Kaly A. Mueller, Kelly E. Glajch, Alexandra N. Mills, Sheena Chew, Sali M.K. Farhan, Eric J. Granucci, Ghazaleh Sadri-Vakili, Tiziana Petrozziello, James Chan
Publikováno v:
Muscle & Nerve. 62:272-283
Background The exact mechanisms underlying neuroinflammation and how they contribute to amyotrophic lateral sclerosis (ALS) pathogenesis remain unclear. One possibility is the secretion of neurotoxic factors, such as lipocalin-2 (LCN2), that lead to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d6f39b6d15f38bc956da447278e0c2
https://doi.org/10.1002/mus.26911
https://doi.org/10.1002/mus.26911
Autor:
Patrick M. Dooley, Bradley T. Hyman, Pia Kivisäkk, James D. Berry, Teresa Gomez-Isla, Tiziana Petrozziello, Steven E. Arnold, Ghazaleh Sadri-Vakili, Bianca A. Trombetta, Ana C. Amaral, James Chan, Tara L. Spires-Jones, Alexandra N. Mills, Derek H. Oakley, Anubrata Ghosal, Caitlin Commins, Merit Cudkowicz, Simon Dujardin, Sali M K Farhan, Theresa R Connors, Evan A. Bordt, Spencer E. Kim
Publikováno v:
Brain pathology (Zurich, Switzerland). 32(2)
Although the molecular mechanisms underlying amyotrophic lateral sclerosis (ALS) are not yet fully understood, several studies report alterations in tau phosphorylation in both sporadic and familial ALS. Recently, we have demonstrated that phosphoryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1213b8764c788efc75c47803b3709591
https://pubmed.ncbi.nlm.nih.gov/34779076
https://pubmed.ncbi.nlm.nih.gov/34779076
Autor:
Simon Dujardin, Benjamin A Devlin, James D. Berry, Tara L. Spires-Jones, Patrick M. Dooley, M. Catarina Silva, Sali M.K. Farhan, Ellen Sapp, Derek H. Oakley, Andreas Neueder, Merit Cudkowicz, Alexandra N. Mills, Khashayar Vakili, Spencer E. Kim, Evan A. Bordt, Bradley T. Hyman, Abigail A. Obeng-Marnu, Christopher M. Henstridge, Marian DiFiglia, Stephen J. Haggarty, Ana C. Amaral, Ghazaleh Sadri-Vakili, Staci D. Bilbo, Tiziana Petrozziello
Publikováno v:
Molecular neurobiology. 59(1)
Understanding the mechanisms underlying amyotrophic lateral sclerosis (ALS) is crucial for the development of new therapies. Recent evidence suggest that tau may be involved in ALS pathogenesis. Here, we demonstrated that hyperphosphorylated tau (pTa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7984438dcc250ecd6de431048e25da
https://pubmed.ncbi.nlm.nih.gov/34757590
https://pubmed.ncbi.nlm.nih.gov/34757590
Autor:
Eric J. Granucci, David R. Elmaleh, Merit Cudkowicz, Alexandra N. Mills, James D. Berry, Ghazaleh Sadri-Vakili, Danielle McGinty, Sabrina Paganoni, Hoang Le, Ana Griciuc, Amanda M. Dios, Rudolph E. Tanzi, João D. Pereira, Kaly A. Mueller
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Accumulating evidence suggests that neuroinflammatory processes are implicated in the initiation and progression of amyotrophic lateral sclerosis (ALS). Previous reports have demonstrated an increase in microgliosis and astrogliosis in the lumbar spi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32853a341c26a4ce7a12df14a49b3b95
http://link.springer.com/article/10.1038/s41598-019-53982-w
http://link.springer.com/article/10.1038/s41598-019-53982-w
Autor:
Anubrata Ghosal, Ghazaleh Sadri-Vakili, Ana C. Amaral, Bradley T. Hyman, Pia Kivisäkk, Spencer E. Kim, Simon Dujardin, Sali M.K. Farhan, Bianca A. Trombetta, Evan A. Bordt, Teresa Gomez-Isla, Alexandra N. Mills, Patrick M. Dooley, Tara L. Spires-Jones, James Chan, James D. Berry, Merit Cudkowicz, Steven E. Arnold, Tiziana Petrozziello
Although the molecular mechanisms underlying amyotrophic lateral sclerosis (ALS) are not yet fully understood, recent studies have described alterations in tau protein in both sporadic and familial ALS. However, it is unclear whether alterations in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9119eb6643a939f7b55760763878995a
https://doi.org/10.1101/2020.12.30.20248944
https://doi.org/10.1101/2020.12.30.20248944
Autor:
Nutan Sharma, Cid Czarina E. Diesta, D. Cristopher Bragg, Gierold Paul A. Legarda, Tiziana Petrozziello, Ellen B. Penney, Christine A. Vaine, Ghazaleh Sadri-Vakili, Edwin L. Muñoz, Regina Macalintal-Canlas, Laurie J. Ozelius, Cara Fernandez-Cerado, Alexandra N. Mills, Mark A. Ang, M. Salvie Velasco-Andrada, Patrick J. Acuña, Geraldine Acuña-Sunshine
Publikováno v:
Neurobiology of Disease, Vol 144, Iss, Pp 105032-(2020)
Neuroinflammation plays a pathogenic role in neurodegenerative diseases and recent findings suggest that it may also be involved in X-linked Dystonia-Parkinsonism (XDP) pathogenesis. Previously, fibroblasts and neuronal stem cells derived from XDP pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009182880af6f2c5f987719acf027771
http://www.sciencedirect.com/science/article/pii/S0969996120303077
http://www.sciencedirect.com/science/article/pii/S0969996120303077
Autor:
Kaly A. Mueller, Jonathan D. Glass, Paul Cernasov, Jacob M. Hooker, Alexandra N. Mills, Mohamad J. Alshikho, James D. Berry, Amanda M. Dios, Nicole R. Zürcher, Ghazaleh Sadri-Vakili, Tonya M. Gilbert, Eric J. Granucci, Suma Babu, Nazem Atassi
Publikováno v:
MusclenerveREFERENCES. 60(4)
Introduction There is an unmet need for mechanism-based biomarkers and effective disease modifying treatments in amyotrophic lateral sclerosis (ALS). Previous findings have provided evidence that histone deacetylases (HDAC) are altered in ALS, provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90352c95d32efaa8a37299a9d3f4a5aa
https://pubmed.ncbi.nlm.nih.gov/31241177
https://pubmed.ncbi.nlm.nih.gov/31241177
Autor:
Laurie J. Ozelius, Kelly E. Glajch, D. Cristopher Bragg, Geraldine Acuña, Edwin L. Muñoz, Regina Macalintal-Canlas, Christine A. Vaine, Naoto Ito, Nutan Sharma, Gierold Paul A. Legarda, Tiziana Petrozziello, Mark A. Ang, M. Salvie Velasco-Andrada, Ghazaleh Sadri-Vakili, Patrick J. Acuña, Cara Fernandez-Cerado, Alexandra N. Mills, Cid Czarina E. Diesta, William T. Hendriks, Kaly A. Mueller, Ellen B. Penney, Amanda M. Dios, Kotchaphorn Mangkalaphiban
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243655 (2020)
PLoS ONE
PLoS ONE
X-linked Dystonia-Parkinsonism (XDP) is a neurodegenerative disease linked to an insertion of a SINE-VNTR-Alu (SVA)-type retrotransposon within an intron of TAF1. This SVA insertion induces aberrant TAF1 splicing and partial intron retention, thereby
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08493bdf9097888220d01a44333daaa9
https://doi.org/10.1371/journal.pone.0243655
https://doi.org/10.1371/journal.pone.0243655