Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alexandra N McMellen"'
Autor:
Justine M Pinskey, Tyler M Hoard, Xiao-Feng Zhao, Nicole E Franks, Zoë C Frank, Alexandra N McMellen, Roman J Giger, Benjamin L Allen
Publikováno v:
eLife, Vol 11 (2022)
Hedgehog signaling controls tissue patterning during embryonic and postnatal development and continues to play important roles throughout life. Characterizing the full complement of Hedgehog pathway components is essential to understanding its wide-r
Externí odkaz:
https://doaj.org/article/eb6803f338494564be79fdc9c0037568
Autor:
Tyler M Hoard, Justine M Pinskey, Xiao-Feng Zhao, Nicole E Franks, Zoë C Frank, Alexandra N McMellen, Roman J Giger, Benjamin L Allen
Publikováno v:
eLife. 11
Hedgehog signaling controls tissue patterning during embryonic and postnatal development and continues to play important roles throughout life. Characterizing the full complement of Hedgehog pathway components is essential to understanding its wide-
Autor:
Justine M. Pinskey, Benjamin L. Allen, Roman J. Giger, Nicole E. Franks, Alexandra N. McMellen
Publikováno v:
The Journal of biological chemistry. 292(37)
Hedgehog (HH) signaling critically regulates embryonic and postnatal development as well as adult tissue homeostasis, and its perturbation can lead to developmental disorders, birth defects, and cancers. Neuropilins (NRPs), which have well-defined ro
Autor:
Pinskey, Justine M., Hoard, Tyler M., Xiao-Feng Zhao, Franks, Nicole E., Frank, Zoë C., McMellen, Alexandra N., Giger, Roman J., Allen, Benjamin L.
Publikováno v:
eLife; 10/11/2022, p1-25, 25p
Autor:
Alexandra McMellen, Benjamin G. Bitler
Publikováno v:
Clinical Cancer Research. 26:A51-A51
The purpose of this study is to define the role of AP-1 mediated DNA repair in PARP inhibitor (PARPi)-resistant high-grade serous ovarian cancer (HGSOC). AP-1 is a dimeric transcription factor comprising Jun, Fos, and/or ATF proteins and its signalin