Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alexandra Matzke"'
Autor:
Charanya Rengarajan, Alexandra Matzke, Luisa Reiner, Véronique Orian-Rousseau, Steffen Scholpp
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86373 (2014)
Tightly controlled concentration gradients of morphogens provide positional information and thus regulate tissue differentiation and morphogenesis in multicellular organisms. However, how such morphogenetic fields are formed and maintained remains de
Externí odkaz:
https://doaj.org/article/381d1f1716484bc2b4f0f103c86cf943
Autor:
Susanne Hasenauer, Dieter Malinger, David Koschut, Giuseppina Pace, Alexandra Matzke, Anja von Au, Véronique Orian-Rousseau
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
Externí odkaz:
https://doaj.org/article/ef8e11bc79cc4dd095c680ef63dc3e64
Autor:
Susanne Hasenauer, Dieter Malinger, David Koschut, Giuseppina Pace, Alexandra Matzke, Anja von Au, Véronique Orian-Rousseau
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62357 (2013)
Receptor Tyrosine Kinases (RTKs) are involved in many cellular processes and play a major role in the control of cell fate. For these reasons, RTK activation is maintained under tight control. Met is an essential RTK that induces proliferation, diffe
Externí odkaz:
https://doaj.org/article/afe26a70d2e54dc38d1fdd683d3781da
Autor:
Véronique Orian-Rousseau, Elmire Hartmans, Arend Karrenbeld, Gooitzen M. van Dam, Derk Jan A. de Groot, Wouter B. Nagengast, Rudolf S N Fehrmann, Alexandra Matzke-Ogi, Steven de Jong
Publikováno v:
Theranostics, 7 (2), 482-492
Theranostics, 7(2), 482-492. IVYSPRING INT PUBL
Theranostics
Theranostics, 7(2), 482-492. IVYSPRING INT PUBL
Theranostics
Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. High adenoma miss rates, especially seen in high-risk patients, demand for better endoscopic detection. By fluorescently 'highlighting' specific molecular characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ec6f9408ca3f4a653da20f10fd2893
Autor:
Alexandra Matzke-Ogi, Véronique Orian-Rousseau, Pavel A. Levkin, Linxian Li, Parvesh Wadhwani, Mark E. Schmitt
Publikováno v:
Advanced Science
In article 1600202, CD44v6 peptide functionalized nanoparticles are fabricated in a facile and controllable way to selectively bind to tumor cells with highly efficient anticancer and antimetastatic properties by Veronique Orian‐Rousseau, Pavel A.
Autor:
Oliver Coutelle, Martin Augsten, Alexandra Matzke-Ogi, Tina Heumann, Thorsten Läufer, Vanessa Al-Rawi
Publikováno v:
Cancer Research. 79:4855-4855
Introduction: CD44v6, a member of the CD44 family, is an essential co-receptor for c-MET, RON and VEGFR-2. The receptor tyrosine kinases (RTKs) c-MET and RON, are key players in tumorigenic pathways, are activated by the ligands HGF and MSP, respecti
Autor:
Thomas Lindner, Amir Abdollahi, Katharina Jannasch, Véronique Orian-Rousseau, Jörg Kleeff, Alexandra Matzke-Ogi, Christian Schwager, Beatrix Fuchs, Marine Shatirishvili, Walter Mier, Owen J. Sansom, Jennifer P. Morton, Sara Chiblak, Arne Warth, Frauke Alves, Helmut Ponta, Bouchra Tawk
Background & Aims\ud \ud Cancer cells with high metastatic potential and stem cell–like characteristics express the cell surface marker CD44. CD44 isoforms that include the v6 exon are co-receptors for the receptor tyrosine kinases MET and Vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61509b06129a130a2f5f9f0c80311000
https://eprints.gla.ac.uk/116680/7/116680.pdf
https://eprints.gla.ac.uk/116680/7/116680.pdf
Autor:
Vanessa Al-Rawi, Martin Augsten, Thorsten Läufer, Oliver Coutelle, Birgit Hotz, Yvonne Heneka, Alexandra Matzke-Ogi
Publikováno v:
Cancer Research. 78:3960-3960
Introduction: In cancer patients, the development of metastases is associated with a poor clinical prognosis. Metastatic dissemination requires cancer cells to detach from the primary tumor and invade adjacent or distant tissue. This process involves
Autor:
Gerhard Christofori, Véronique Orian-Rousseau, Helmut Ponta, Alexandra Matzke, Vivienne Olaku, Imke Albrecht, Anna M. Laib, Mélanie Héroult, Kurt Ballmer-Hofer, Hellmut G. Augustin, Martina Tremmel
Publikováno v:
Blood. 114:5236-5244
A specific splice variant of the CD44 cell- surface protein family, CD44v6, has been shown to act as a coreceptor for the receptor tyrosine kinase c-Met on epithelial cells. Here we show that also on endothelial cells (ECs), the activity of c-Met is
Autor:
Helmut Ponta, Thor Kastilan, Giuseppina Pace, Véronique Orian-Rousseau, Alexandra Matzke, Peter Herrlich, Helen Morrison
Publikováno v:
Molecular Biology of the Cell. 18:76-83
In several types of cells, the activation of the receptor tyrosine kinase c-Met by its ligand hepatocyte growth factor (HGF) requires the coreceptor CD44v6. The CD44 extracellular domain is necessary for c-Met autophosphorylation, whereas the intrace