Výsledky vyhledávání - "Alexandra Matschiner"

Glucagon-like Peptide-2 (GLP-2) Treatment Reduces Gvhd-Related Mortality in a Pre-Clinical Transplant Model Via Expansion of Macrophages with Tolerogenic Potential

Autor: Ran Reshef, Tiffany Thomas, Huihui Ma, Alexandra Matschiner, Felix D Rozenberg, Rajat Bansal, David Harle, Ximi K. Wang, Markus Y. Mapara, Yi Zhang, Kirubel S Belay, Elisha Y. Pinker, Rodney J.M. Macedo Gonzales, Anne-Catrin Uhlemann, Stephen M. Lagana

Publikováno v: Blood. 136:26-28

The gastrointestinal (GI) tract is a major target in GVHD. Conditioning-induced damage and mucosal barrier disruption are important factors in GVHD, however therapies targeting these processes have not been identified. Glucagon-like-peptide 2 (GLP-2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd7d3fd5106db67038211c268fd4ca03
https://doi.org/10.1182/blood-2020-143105

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Abstract B2: Coexpression of effector T cell-associated chemokine receptors defines T-cell subsets with different roles in antitumor response and toxicity of dual checkpoint blockade

Autor: Alexandra Matschiner, Ran Reshef, Ximi K. Wang, David Harle, Rodney J.M. Macedo Gonzales

Publikováno v: Cancer Immunology Research. 8:B2-B2

Dual checkpoint blockade has yielded impressive clinical responses in cancer treatment, but only a subset of patients responds and immune-related adverse events (irAE) are common, frequently leading to treatment discontinuation. Both CCR5 and CXCR3 e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::090e8eb38e0bfad748fca520d554203f
https://doi.org/10.1158/2326-6074.tumimm19-b2

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