Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alexandra MacKinnon"'
Autor:
Mahtab Tavasoli, Sarah Lahire, Stanislav Sokolenko, Robyn Novorolsky, Sarah Anne Reid, Abir Lefsay, Meredith O. C. Otley, Kitipong Uaesoontrachoon, Joyce Rowsell, Sadish Srinivassane, Molly Praest, Alexandra MacKinnon, Melissa Stella Mammoliti, Ashley Alyssa Maloney, Marina Moraca, J. Pedro Fernandez-Murray, Meagan McKenna, Christopher J. Sinal, Kanneboyina Nagaraju, George S. Robertson, Eric P. Hoffman, Christopher R. McMaster
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Mutations in the CHKB gene cause muscular dystrophy. Here, the authors show that in mouse models of the disease changes in lipid metabolism are associated with decreased PPAR signaling, and show PPAR agonists can rescue expression of injury markers i
Externí odkaz:
https://doaj.org/article/8397e994802c4cd4af32c80fc27420fc
Autor:
Mahtab Tavasoli, Tiam Feridooni, Hirad Feridooni, Stanislav Sokolenko, Abhishek Mishra, Abir Lefsay, Sadish Srinivassane, Sarah Anne Reid, Joyce Rowsell, Molly Praest, Alexandra MacKinnon, Melissa Mammoliti, Ashley Alyssa Maloney, Marina Moraca, Kitipong Uaesoontrachoon, Kanneboyina Nagaraju, Eric P. Hoffman, Kishore B.S. Pasumarthi, Christopher R. McMaster
Publikováno v:
The Journal of biological chemistry. 298(3)
The CHKB gene encodes choline kinase β, which catalyzes the first step in the biosynthetic pathway for the major phospholipid phosphatidylcholine. Homozygous loss-of-function variants in human CHKB are associated with a congenital muscular dystrophy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbe3daceaed1daadb46aa421268490d
https://pubmed.ncbi.nlm.nih.gov/35151687
https://pubmed.ncbi.nlm.nih.gov/35151687
Autor:
Joyce Rowsell, Mahtab Tavasoli, Abir Lefsay, Melissa Mammoliti, Molly Praest, J. Pedro Fernández-Murray, Kitipong Uaesoontrachoon, Kanneboyina Nagaraju, Sadish Srinivassane, Sarah Lahire, Ashley Maloney, Eric P. Hoffman, Stanislav Sokolenko, Christopher R. McMaster, Marina Moraca, Alexandra MacKinnon
CHKB encodes one of two mammalian choline kinase enzymes that catalyze the first step in the synthesis of the major membrane phospholipid, phosphatidylcholine (PC). In humans, inactivation of the CHKB gene causes a recessive form of a rostral-to-caud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ed1973477bc63e7aebf2789c8a358cb
https://doi.org/10.21203/rs.3.rs-64129/v1
https://doi.org/10.21203/rs.3.rs-64129/v1
Autor:
Mahtab Tavasoli, Sarah Lahire, Stanislav Sokolenko, Robyn Novorolsky, Sarah Anne Reid, Abir Lefsay, Meredith O. C. Otley, Kitipong Uaesoontrachoon, Joyce Rowsell, Sadish Srinivassane, Molly Praest, Alexandra MacKinnon, Melissa Stella Mammoliti, Ashley Alyssa Maloney, Marina Moraca, J. Pedro Fernandez-Murray, Meagan McKenna, Christopher J. Sinal, Kanneboyina Nagaraju, George S. Robertson, Eric P. Hoffman, Christopher R. McMaster
Publikováno v:
Nature communications. 13(1)
CHKB encodes one of two mammalian choline kinase enzymes that catalyze the first step in the synthesis of the membrane phospholipid phosphatidylcholine. In humans and mice, inactivation of the CHKB gene (Chkb in mice) causes a recessive rostral-to-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c03787b601c23aaa02007697fbedd85
https://pubmed.ncbi.nlm.nih.gov/35322809
https://pubmed.ncbi.nlm.nih.gov/35322809
Autor:
Kitipong Uaesoontrachoon, Romain Beauvois, Taishi Yamashita, Jordan Warford, Youhei Satou, Swati Mummidivarpu, Joyce Rowsell, Kevork Mekhssian, Eric P. Hoffman, Amanda Mullen, Anahita Keyhani, Maja Malbasic, William Ross, Hélène Montpetit, Hironori Osaki, Alexandra MacKinnon, Yetrib Hathout, Marina Moraca, Kanneboyina Nagaraju, Molly Praest, Mark Matyas, Sadish Srinivassane
Publikováno v:
Biomarkers in medicine. 13(14)
Aim: Detection of drug-induced dystrophin in patient muscle biopsy is a surrogate outcome measure for Duchenne muscular dystrophy. We sought to establish and validate an orthogonal approach to measurement of dystrophin protein and RNA in muscle biops
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13290ebd63685848cdd582390d108d7e
https://pubmed.ncbi.nlm.nih.gov/31379197
https://pubmed.ncbi.nlm.nih.gov/31379197
Autor:
Tina Duong, Jack Vandermeulen, Adati Phadke, Kanneboyina Nagaraju, Arpana Sali, Alexandra MacKinnon, Micaela Iantorno
Publikováno v:
Medicine & Science in Sports & Exercise. 49:771
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::410f281019b4ea5c937eec533e7233a1
https://doi.org/10.1249/01.mss.0000519054.49300.dc
https://doi.org/10.1249/01.mss.0000519054.49300.dc