Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alexandra M. Pietersen"'
Autor:
Victor Ho, Shi Yun Yeo, Kamini Kunasegaran, Duvini De Silva, Gerard A. Tarulli, P. Mathijs Voorhoeve, Alexandra M. Pietersen
Publikováno v:
BioTechniques, Vol 54, Iss 4, Pp 208-212 (2013)
Since tissues and tumors are heterogenous populations containing different cell types, their transcriptomes are blends of multiple mRNA expression profiles. Although fluorescence-activated cell sorting (FACS) allows isolation of individual cell types
Externí odkaz:
https://doaj.org/article/6ef278a150b744909383c21aceb294fd
Autor:
Kamini Kunasegaran, Victor Ho, Ted H-T Chang, Duvini De Silva, Martijn L Bakker, Vincent M Christoffels, Alexandra M Pietersen
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110191 (2014)
The transcriptional repressor Tbx3 is involved in lineage specification in several tissues during embryonic development. Germ-line mutations in the Tbx3 gene give rise to Ulnar-Mammary Syndrome (comprising reduced breast development) and Tbx3 is requ
Externí odkaz:
https://doaj.org/article/4b372e78434c49caa89df327d62af04f
Autor:
Maarten van Lohuizen, Alexandra M Pietersen, Jos Jonkers, Paulien Cornelissen-Steijger, Ellen Tanger, Bastiaan Evers, Asheeta A. Prasad
Publikováno v:
Current Biology. 18(14):1094-1099
Summary PolycombGroup (PcG) proteins are epigenetic silencers involved in maintaining cellular identity, and their deregulation can result in cancer [1]. Mice without the PcG gene Bmi1 are runted and suffer from progressive loss of hematopoietic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490c8fbcf34975e196160e5f7fd8e417
Publikováno v:
Current Opinion in Cell Biology. 20:201-207
Polycomb group proteins (PcGs) are involved in gene repression through chromatin modifications and required for the maintenance of both embryonic and adult stem cells. Genome-wide studies demonstrate that genes targeted by PcG are predominantly devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0169231da3e0a7f7b0b9175aee0def39
https://doi.org/10.1016/j.ceb.2008.01.004
https://doi.org/10.1016/j.ceb.2008.01.004
Publikováno v:
BMC Developmental Biology
Background Alveoli, the milk-producing units of the mammary gland, are generated during pregnancy by collaboration of different epithelial cell types. We present the first analysis of transcriptional changes within the hormone sensing population duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f74e368a6861baf42a4e36d9c67555
https://doi.org/10.1186/s12861-015-0058-9
https://doi.org/10.1186/s12861-015-0058-9
Autor:
Marjolijn M van der Eb, Alexandra M Pietersen, Frank M Speetjens, Peter JK Kuppen, Cornelis JH van de Velde, Mathieu HM Noteborn, Rob C Hoeben
Publikováno v:
Cancer Gene Therapy. 9:53-61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb1a0e26a3f279c53fc14b5cd0515ab1
https://doi.org/10.1038/sj/cgt/7700397
https://doi.org/10.1038/sj/cgt/7700397
Autor:
Martijn L. Bakker, Vincent M. Christoffels, Kamini Kunasegaran, Duvini De Silva, Victor Ho, Ted H-. T. Chang, Alexandra M Pietersen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 10, p e110191 (2014)
PLoS ONE, 9(10). Public Library of Science
PLoS ONE, Vol 9, Iss 10, p e110191 (2014)
PLoS ONE, 9(10). Public Library of Science
The transcriptional repressor Tbx3 is involved in lineage specification in several tissues during embryonic development. Germ-line mutations in the Tbx3 gene give rise to Ulnar-Mammary Syndrome (comprising reduced breast development) and Tbx3 is requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2921b75237c111ba139263a697de1a9f
https://doi.org/10.1371/journal.pone.0110191
https://doi.org/10.1371/journal.pone.0110191
Autor:
Jost Seibler, Ellen Wientjens, Ewa M. Michalak, Alexandra M Pietersen, Jos Jonkers, Ellen Tanger, Maarten van Lohuizen, Inka Pawlitzky, Karim Nacerddine, Paulien Cornelissen-Steijger, Vincent Beuger
Publikováno v:
Stem cells (Dayton, Ohio). 31(9)
Specification of the cellular hierarchy in the mammary gland involves complex signaling that remains poorly defined. Polycomb group proteins are known to contribute to the maintenance of stem cell identity through epigenetic modifications, leading to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ebbdfe6c3035c261a0389bb5f61f29f
https://pubmed.ncbi.nlm.nih.gov/23712803
https://pubmed.ncbi.nlm.nih.gov/23712803
Autor:
Dmitry V. Bulavin, Bryan C Tan, Kamini Kunasegaran, Victor Ho, Gerard A. Tarulli, Alexandra M Pietersen, Kakaly Ghosh, Duvini De Silva
Publikováno v:
Breast Cancer Research : BCR
Introduction The molecular circuitry of different cell types dictates their normal function as well as their response to oncogene activation. For instance, mice lacking the Wip1 phosphatase (also known as PPM1D; protein phosphatase magnesium-dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8117e699df06a108cadd8db319c941ae
https://doi.org/10.1186/bcr3381
https://doi.org/10.1186/bcr3381
Autor:
Alexandra M Pietersen, Duvini De Silva, Kamini Kunasegaran, Victor Ho, Gerard A. Tarulli, Shi Yun Yeo, P. Mathijs Voorhoeve
Publikováno v:
BioTechniques. 54(4)
Since tissues and tumors are heterogenous populations containing different cell types, their transcriptomes are blends of multiple mRNA expression profiles. Although fluorescence-activated cell sorting (FACS) allows isolation of individual cell types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fb3751406eb824f01fd8eebd3571f3
https://pubmed.ncbi.nlm.nih.gov/23581467
https://pubmed.ncbi.nlm.nih.gov/23581467