Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alexandra M. Miller"'
Publikováno v:
Translational Oncology, Vol 41, Iss , Pp 101881- (2024)
For patients with central nervous system (CNS) malignancies, liquid biopsies of the cerebrospinal fluid (CSF) may offer an unparalleled source of information about the tumor, with much less risk than traditional biopsies. Two techniques have been ada
Externí odkaz:
https://doaj.org/article/7c291ae422f443cead81496da3273ec4
Publikováno v:
Translational Oncology, Vol 33, Iss , Pp 101688- (2023)
Malignancies involving the central nervous system present unique challenges for diagnosis and monitoring due to the difficulties and risks of direct biopsies and the low specificity and/or sensitivity of other techniques for assessment. In recent yea
Externí odkaz:
https://doaj.org/article/4d172a2cfa4043fb982a50290082c4ed
Autor:
Lauren R. Schaff, Mina Lobbous, Dean Carlow, Ryan Schofield, Igor T. Gavrilovic, Alexandra M. Miller, Jacqueline B. Stone, Anna F. Piotrowski, Ugur Sener, Anna Skakodub, Edward P. Acosta, Kevin J. Ryan, Ingo K. Mellinghoff, Lisa M. DeAngelis, Louis B. Nabors, Christian Grommes
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background High-dose methotrexate (HD-MTX) has broad use in the treatment of central nervous system (CNS) malignancies but confers significant toxicity without inpatient hydration and monitoring. Glucarpidase is a bacterial recombinant enzym
Externí odkaz:
https://doaj.org/article/3e9f2e48ef674472afa6c947189513cd
Autor:
Douglas A. Mata, Jamal K. Benhamida, Andrew L. Lin, Chad M. Vanderbilt, Soo-Ryum Yang, Liliana B. Villafania, Donna C. Ferguson, Philip Jonsson, Alexandra M. Miller, Viviane Tabar, Cameron W. Brennan, Nelson S. Moss, Martin Sill, Ryma Benayed, Ingo K. Mellinghoff, Marc K. Rosenblum, Maria E. Arcila, Marc Ladanyi, Tejus A. Bale
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract A subset of glioblastomas (GBMs) harbors potentially druggable oncogenic FGFR3-TACC3 (F3T3) fusions. However, their associated molecular and clinical features are poorly understood. Here we analyze the frequency of F3T3-fusion positivity, it
Externí odkaz:
https://doaj.org/article/e6a9da3b0b01489295be630dcbaceb95
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 752-759 (2005)
Structures responsible for the onset, propagation, and cessation of generalized seizures are not known. Lesion and microinfusion studies suggest that the substantia nigra pars reticulata (SNR) seizure-controlling network could play a key role. Howeve
Externí odkaz:
https://doaj.org/article/95bad971e4554c1da00abf8758a0d641
Autor:
N. Ari Wijetunga, Alexander G. Goglia, Nils Weinhold, Michael F. Berger, Michael Cislo, Daniel S. Higginson, Kiana Chabot, Ahmed M. Osman, Lauren Schaff, Elena Pentsova, Alexandra M. Miller, Simon N. Powell, Adrienne Boire, Jonathan T. Yang
Publikováno v:
Clinical Cancer Research. 29:775-783
Purpose:Proton craniospinal irradiation (pCSI) is a promising treatment for patients with solid tumor leptomeningeal metastasis (LM). We hypothesize that genetic characteristics before and changes resulting after pCSI will reflect clinical response t
Publikováno v:
Neuro-Oncology Advances. 4:ii33-ii40
Liquid biopsy has emerged as a novel noninvasive tool in cancer diagnostics. While significant strides have been made in other malignancies using liquid biopsy for diagnosis, disease monitoring, and treatment selection, development of these assays ha
Publikováno v:
Neuro-Oncology.
Autor:
Jonathan T. Yang, Adrienne Boire, Simon N. Powell, Alexandra M. Miller, Elena Pentsova, Lauren Schaff, Ahmed M. Osman, Kiana Chabot, Daniel S. Higginson, Michael Cislo, Michael F. Berger, Nils Weinhold, Alexander G. Goglia, N. Ari Wijetunga
Gene set enrichment analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b753d7075320e6f64397662d000cb846
https://doi.org/10.1158/1078-0432.22490585.v1
https://doi.org/10.1158/1078-0432.22490585.v1
Autor:
Jonathan T. Yang, Adrienne Boire, Simon N. Powell, Alexandra M. Miller, Elena Pentsova, Lauren Schaff, Ahmed M. Osman, Kiana Chabot, Daniel S. Higginson, Michael Cislo, Michael F. Berger, Nils Weinhold, Alexander G. Goglia, N. Ari Wijetunga
Supplemental Figure 5. Concordance between plasma and CSF ctDNA variants over time.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87398369dc52ca875f71834836f0bdef
https://doi.org/10.1158/1078-0432.22490600.v1
https://doi.org/10.1158/1078-0432.22490600.v1