Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Alexandra M. Dumitrescu"'
Publikováno v:
BMC Endocrine Disorders, Vol 22, Iss 1, Pp 1-5 (2022)
Abstract Background Graves’ disease (GD) and papillary thyroid cancer (PTC) can be concomitant. The existence of a link between these entities has long been investigated, but a clear correlation hasn’t been established. We report a case of GD res
Externí odkaz:
https://doaj.org/article/a974b0069df340148e661a9e843278fb
Autor:
Christopher M. Carmean, Mizuho Mimoto, Michael Landeche, Daniel Ruiz, Bijoy Chellan, Lidan Zhao, Margaret C. Schulz, Alexandra M. Dumitrescu, Robert M. Sargis
Publikováno v:
Nutrients, Vol 13, Iss 8, p 2894 (2021)
Chronic arsenic exposure via drinking water is associated with diabetes in human pop-ulations throughout the world. Arsenic is believed to exert its diabetogenic effects via multiple mechanisms, including alterations to insulin secretion and insulin
Externí odkaz:
https://doaj.org/article/994eae19d3dd4743858831bdce0960d0
Autor:
Monica Malheiros, França, Lucy, Reeve, Alexandra M, Dumitrescu, Martin, de Bock, Samuel, Refetoff
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 32(8)
We report a 10-month-old girl with familial congenital hypothyroidism harboring a novel heterozygous pathogenic variant in the paired DNA-binding domain of
Autor:
Xiao-Hui Liao, Pablo Avalos, Oksana Shelest, Raz Ofan, Michael Shilo, Catherine Bresee, Shibi Likhite, Jean-Philippe Vit, Heike Heuer, Brian Kaspar, Kathrin Meyer, Alexandra M. Dumitrescu, Samuel Refetoff, Clive N. Svendsen, Gad D. Vatine
Publikováno v:
Thyroid
BACKGROUND: Allan-Herndon-Dudley syndrome (AHDS) is a severe psychomotor disability disorder that also manifests characteristic abnormal thyroid hormone (TH) levels. AHDS is caused by inactivating mutations in monocarboxylate transporter 8 (MCT8), a
Autor:
Federico Salas-Lucia, Marius N Stan, Haleigh James, Aadil Rajwani, Xiao-Hui Liao, Alexandra M Dumitrescu, Samuel Refetoff
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
Context Pregnant women with mutations in the thyroid hormone receptor beta (THRB) gene expose their fetuses to high thyroid hormone (TH) levels shown to be detrimental to a normal fetus (NlFe) but not to an affected fetus (AfFe). However, no informat
Autor:
Federico Salas-Lucia, Monica M. França, James A. Amrhein, J. Elizabeth Weir, Alexandra M. Dumitrescu, Samuel Refetoff
Publikováno v:
Thyroid
We report a patient with congenital hypothyroidism due to athyreosis complicated by a heterozygous thyroid hormone receptor beta (THRβ) gene mutation (R320L), resulting in a severe resistance to thyroid hormone beta phenotype. The proband inherited
Autor:
Monica Malheiros França, Lucy Reeve, Alexandra M. Dumitrescu, Martin de Bock, Samuel Refetoff
Publikováno v:
Thyroid. 32:1000-1002
Autor:
Erin C. Hanlon, Matthew D Ettleson, Alexandra M. Dumitrescu, Marilyn Arosemena, Antonio C. Bianco, Mihai Giurcanu, Olga Duchon
Publikováno v:
Thyroid
Background: L-triiodothyronine (LT3) has been increasingly used in combination with levothyroxine in the treatment of hypothyroidism. A metal coordinated form of LT3, known as poly-zinc-liothyronine (PZL), avoided in rats the typical triiodothyronine
Autor:
Antonio C. Bianco, Alina German, Samuel Refetoff, Xiao Hui Liao, Gustavo W. Fernandes, Monica M. França, Alexandra M. Dumitrescu
Publikováno v:
Thyroid. 31:202-207
Background: Iodothyronine deiodinase-1 (D1) selenoenzyme regulates the systemic supply of active thyroid hormone (TH). Transient decrease in D1 enzymatic activity is clinically relevant and adaptive in nonthyroidal illness such as fasting or acute il
Autor:
Lidan Zhao, Christopher M Carmean, Alexandra M. Dumitrescu, Michael Landeche, Bijoy Chellan, Robert M. Sargis
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Selenoproteins are a group of selenocysteine-containing proteins with major roles in cellular antioxidant defense and thyroid hormone metabolism. Selenoprotein expression is determined by hierarchical mechanisms that result in tissue-specific levels.