Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Alexandra M Miller"'
Autor:
Richard A. Hickman, Alexandra M. Miller, Bridget M. Holle, Justin Jee, Si-Yang Liu, Dara Ross, Helena Yu, Gregory J. Riely, Christina Ombres, Alexandra N. Gewirtz, Anne S. Reiner, Subhiksha Nandakumar, Adam Price, Thomas J. Kaley, Maya S. Graham, Chad Vanderbilt, Satshil Rana, Katherine Hill, Kiana Chabot, Carl Campos, Khedoudja Nafa, Neerav Shukla, Matthias Karajannis, Bob Li, Michael Berger, Marc Ladanyi, Elena Pentsova, Adrienne Boire, A. Rose Brannon, Tejus Bale, Ingo K. Mellinghoff, Maria E. Arcila
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract The characterization of genetic alterations in tumor samples has become standard practice for many human cancers to achieve more precise disease classification and guide the selection of targeted therapies. Cerebrospinal fluid (CSF) can serv
Externí odkaz:
https://doaj.org/article/d891582bd5b340c8aff11cbf672c3107
Autor:
Pauline Latzer, Henning Zelba, Florian Battke, Annekathrin Reinhardt, Borong Shao, Oliver Bartsch, Armin Rabsteyn, Johannes Harter, Martin Schulze, Thomas Okech, Alexander Golf, Christina Kyzirakos-Feger, Simone Kayser, Natalia Pieper, Magdalena Feldhahn, Julian Wünsche, Christian Seitz, Dirk Hadaschik, Claus Garbe, Till-Karsten Hauser, Christian la Fougère, Dirk Biskup, Dawn Brooke, David Parker, Uwe M. Martens, Gerald Illerhaus, Deborah T. Blumenthal, Ryan Merrell, Luisa Sánchez Lorenzo, Máté Hidvégi, Paula de Robles, Sied Kebir, William W. Li, Vincent W. Li, Matthew Williams, Alexandra M. Miller, Santosh Kesari, Michael Castro, Annick Desjardins, David M. Ashley, Henry S. Friedman, Patrick Y. Wen, Elisabeth C. Neil, Fabio M. Iwamoto, Bence Sipos, Karsten Geletneky, Lars Zender, Martin Glas, David A. Reardon, Saskia Biskup
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Current treatment outcome of patients with glioblastoma (GBM) remains poor. Following standard therapy, recurrence is universal with limited survival. Tumors from 173 GBM patients are analysed for somatic mutations to generate a personalized
Externí odkaz:
https://doaj.org/article/98a07e6f1b4647369483ebef527a8f94
Publikováno v:
Translational Oncology, Vol 41, Iss , Pp 101881- (2024)
For patients with central nervous system (CNS) malignancies, liquid biopsies of the cerebrospinal fluid (CSF) may offer an unparalleled source of information about the tumor, with much less risk than traditional biopsies. Two techniques have been ada
Externí odkaz:
https://doaj.org/article/7c291ae422f443cead81496da3273ec4
Publikováno v:
Translational Oncology, Vol 33, Iss , Pp 101688- (2023)
Malignancies involving the central nervous system present unique challenges for diagnosis and monitoring due to the difficulties and risks of direct biopsies and the low specificity and/or sensitivity of other techniques for assessment. In recent yea
Externí odkaz:
https://doaj.org/article/4d172a2cfa4043fb982a50290082c4ed
Autor:
Lauren R. Schaff, Mina Lobbous, Dean Carlow, Ryan Schofield, Igor T. Gavrilovic, Alexandra M. Miller, Jacqueline B. Stone, Anna F. Piotrowski, Ugur Sener, Anna Skakodub, Edward P. Acosta, Kevin J. Ryan, Ingo K. Mellinghoff, Lisa M. DeAngelis, Louis B. Nabors, Christian Grommes
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background High-dose methotrexate (HD-MTX) has broad use in the treatment of central nervous system (CNS) malignancies but confers significant toxicity without inpatient hydration and monitoring. Glucarpidase is a bacterial recombinant enzym
Externí odkaz:
https://doaj.org/article/3e9f2e48ef674472afa6c947189513cd
Autor:
Douglas A. Mata, Jamal K. Benhamida, Andrew L. Lin, Chad M. Vanderbilt, Soo-Ryum Yang, Liliana B. Villafania, Donna C. Ferguson, Philip Jonsson, Alexandra M. Miller, Viviane Tabar, Cameron W. Brennan, Nelson S. Moss, Martin Sill, Ryma Benayed, Ingo K. Mellinghoff, Marc K. Rosenblum, Maria E. Arcila, Marc Ladanyi, Tejus A. Bale
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract A subset of glioblastomas (GBMs) harbors potentially druggable oncogenic FGFR3-TACC3 (F3T3) fusions. However, their associated molecular and clinical features are poorly understood. Here we analyze the frequency of F3T3-fusion positivity, it
Externí odkaz:
https://doaj.org/article/e6a9da3b0b01489295be630dcbaceb95
Autor:
N. Ari Wijetunga, Alexander G. Goglia, Nils Weinhold, Michael F. Berger, Michael Cislo, Daniel S. Higginson, Kiana Chabot, Ahmed M. Osman, Lauren Schaff, Elena Pentsova, Alexandra M. Miller, Simon N. Powell, Adrienne Boire, Jonathan T. Yang
Publikováno v:
Clinical Cancer Research. 29:775-783
Purpose:Proton craniospinal irradiation (pCSI) is a promising treatment for patients with solid tumor leptomeningeal metastasis (LM). We hypothesize that genetic characteristics before and changes resulting after pCSI will reflect clinical response t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b42fa98bc9483c6a1456f1f64be287
https://doi.org/10.1158/1078-0432.ccr-22-2434
https://doi.org/10.1158/1078-0432.ccr-22-2434
Publikováno v:
Neuro-Oncology Advances. 4:ii33-ii40
Liquid biopsy has emerged as a novel noninvasive tool in cancer diagnostics. While significant strides have been made in other malignancies using liquid biopsy for diagnosis, disease monitoring, and treatment selection, development of these assays ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f9d379911ffe6caf7a3ab6b227f1a7
https://doi.org/10.1093/noajnl/vdac034
https://doi.org/10.1093/noajnl/vdac034
Publikováno v:
Neuro-Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8bc34a65289c458664ccf2a5ef739ba
https://doi.org/10.1093/neuonc/noad075
https://doi.org/10.1093/neuonc/noad075
Autor:
Jonathan T. Yang, Adrienne Boire, Simon N. Powell, Alexandra M. Miller, Elena Pentsova, Lauren Schaff, Ahmed M. Osman, Kiana Chabot, Daniel S. Higginson, Michael Cislo, Michael F. Berger, Nils Weinhold, Alexander G. Goglia, N. Ari Wijetunga
Alterations called after MSK-IMPACT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d9729f2833f06b40f3968e08196d9a
https://doi.org/10.1158/1078-0432.22490594
https://doi.org/10.1158/1078-0432.22490594
