Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alexandra M Hetherington"'
Autor:
Alexandra M Stoianov, Debra L Robson, Alexandra M Hetherington, Cynthia G Sawyez, Nica M Borradaile
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131269 (2015)
Elongation factor 1A-1 (eEF1A-1) has non-canonical functions in regulation of the actin cytoskeleton and apoptosis. It was previously identified through a promoter-trap screen as a mediator of fatty acid-induced cell death (lipotoxicity), and was fou
Externí odkaz:
https://doaj.org/article/bcb5f74d543d4e1db84f95f56925ccc0
Publikováno v:
Data in Brief
Data in Brief, Vol 10, Iss C, Pp 385-389 (2017)
Data in Brief, Vol 10, Iss C, Pp 385-389 (2017)
As nonalcoholic fatty liver disease progresses to end-stage diseases, including fibrosis, cirrhosis and hepatocellular carcinoma, fibrotic activated hepatic stellate cells and cancerous epithelial cells can become abundant, changing the cellular comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87214c23413522f6db7fb6a8eeea32d
http://europepmc.org/articles/PMC5192242
http://europepmc.org/articles/PMC5192242
Autor:
Nica M. Borradaile, Cynthia G. Sawyez, Alexandra M. Hetherington, Emma Zilberman, Debra L. Robson, Alexandra M. Stoianov
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 4, Pp 1648-1662 (2016)
Background/Aims: Nonalcoholic fatty liver disease (NAFLD) progression to fibrosis, cirrhosis and hepatocellular carcinoma, alters the cellular composition of this organ. During late-stage NAFLD, fibrotic and possibly cancerous cells can proliferate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bf6cd64aa1ac0f36bb6e41336f18c8
http://www.karger.com/Article/FullText/447866
http://www.karger.com/Article/FullText/447866
Autor:
Yun Jin Chen, Kia M. Peters, Rennian Wang, Krisha Patel, Taylor Woolnough, John P. Kennelly, René L. Jacobs, Meg Schuurman, Kelly-Ann Leonard, Cynthia G. Sawyez, Rachel B. Wilson, Brian G. Sutherland, Richard Zhang, Nica M. Borradaile, Alexandra M. Hetherington
Publikováno v:
Paediatrics Publications
Inhibition of eukaryotic elongation factor 1A1 (EEF1A1) with the marine compound didemnin B decreases lipotoxic HepG2 cell death in vitro and improves early stage non-alcoholic fatty liver disease (NAFLD) in young genetically obese mice. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e81fed7813534314cab980805692e26
https://doi.org/10.1016/j.phrs.2020.105208
https://doi.org/10.1016/j.phrs.2020.105208
Autor:
Debra L. Robson, Nica M. Borradaile, Alexandra M. Stoianov, Cynthia G. Sawyez, Alexandra M. Hetherington
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0131269 (2015)
PLoS ONE, Vol 10, Iss 6, p e0131269 (2015)
Elongation factor 1A-1 (eEF1A-1) has non-canonical functions in regulation of the actin cytoskeleton and apoptosis. It was previously identified through a promoter-trap screen as a mediator of fatty acid-induced cell death (lipotoxicity), and was fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4ac1e0ac9259caf6e82c2872d14b1d
https://pubmed.ncbi.nlm.nih.gov/26102086
https://pubmed.ncbi.nlm.nih.gov/26102086
Publikováno v:
Data in Brief, Vol 10, Iss C, Pp 385-389 (2017)
As nonalcoholic fatty liver disease progresses to end-stage diseases, including fibrosis, cirrhosis and hepatocellular carcinoma, fibrotic activated hepatic stellate cells and cancerous epithelial cells can become abundant, changing the cellular comp
Externí odkaz:
https://doaj.org/article/84ccc6e8b43c4cf88e18cdc907383f44
Autor:
Alexandra M. Hetherington, Cynthia G. Sawyez, Emma Zilberman, Alexandra M. Stoianov, Debra L. Robson, Nica M. Borradaile
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 4, Pp 1648-1662 (2016)
Background/Aims: Nonalcoholic fatty liver disease (NAFLD) progression to fibrosis, cirrhosis and hepatocellular carcinoma, alters the cellular composition of this organ. During late-stage NAFLD, fibrotic and possibly cancerous cells can proliferate a
Externí odkaz:
https://doaj.org/article/b1356ecf499f4b52921152aac4bb28de