Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexandra M Durrant"'
Publikováno v:
F1000Research, Vol 7 (2018)
Central nervous system (CNS) pericytes regulate critical functions of the neurovascular unit in health and disease. CNS pericytes are an attractive pharmacological target for their position within the neurovasculature and for their role in neuroinfla
Externí odkaz:
https://doaj.org/article/9bcb6daffd72413e9c151c4ecc3ab294
Autor:
Richard P. Hulse, David O. Bates, Lucy F. Donaldson, William Robert Ashby, Fatimah Almahasneh, Alexandra M. Durrant, Samuel M. Bestall, Catherine E. Moss, Kurt Ballmer-Hofer, Andrew V. Benest, Nicholas Beazley-Long, Zoe Blackley, Masanori Hirashima
Publikováno v:
Brain, Behavior, and Immunity
BRAIN BEHAVIOR AND IMMUNITY
BRAIN BEHAVIOR AND IMMUNITY
Highlights • Targeting VEGFR2 prevents secondary allodynia in inflammatory arthritis models. • Anti-VEGFR2 reduces vascular ICAM-1 and microglia in the dorsal horn. • Anti-VEGFR2 inhibits monocyte attachment to brain endothelial cells. • We p
PURPOSE OF THE REVIEW: The importance of the blood-brain barrier and neuroinflammation in neurodegenerative conditions is becoming increasingly apparent, yet very little is known about these neurovascular functions in non-malignant disease chronic pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54c2548913fd07233ae7ec7d818416b
https://europepmc.org/articles/PMC6027993/
https://europepmc.org/articles/PMC6027993/
Publikováno v:
F1000Research
Central nervous system (CNS) pericytes regulate critical functions of the neurovascular unit in health and disease. CNS pericytes are an attractive pharmacological target for their position within the neurovasculature and for their role in neuroinfla